| Budget Amount *help |
¥44,200,000 (Direct Cost: ¥34,000,000、Indirect Cost: ¥10,200,000)
Fiscal Year 2021: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
Fiscal Year 2019: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
Fiscal Year 2018: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
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| Outline of Final Research Achievements |
The aim of this study was to clarify the importance of AMOR as an signaling molecule in plant cell-to-cell communication and how it is used for signal transduction, using the biologically active sugar chain AMOR. In order to explore the new functions of AMOR and to analyze the mechanism of AMOR reception, we succeeded in modifying AMOR by organic chemical synthesis. Based on this, we established monoclonal antibodies that specifically recognize the AMOR structure (methylglucuronosylgalactose). In addition, multimeric AMOR molecules were produced and high activity per molecule was confirmed; it is expected that Torenia crustacea will be useful for further analysis of the AMOR synthesis system and candidate receptor genes in combination of developed molecular tools.
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