• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A new light-energy flow model linking the Earth's ecosystem and the sun

Research Project

Project/Area Number 18H04136
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Review Section Medium-sized Section 63:Environmental analyses and evaluation and related fields
Research InstitutionThe University of Tokyo

Principal Investigator

Yoshizawa Susumu  東京大学, 大学院新領域創成科学研究科, 准教授 (00553108)

Co-Investigator(Kenkyū-buntansha) 岩崎 渉  東京大学, 大学院新領域創成科学研究科, 教授 (50545019)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥39,520,000 (Direct Cost: ¥30,400,000、Indirect Cost: ¥9,120,000)
Fiscal Year 2021: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2020: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2019: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2018: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Keywords微生物生態 / 海洋微生物 / ロドプシン / 光エネルギー / メタゲノム / 光従属栄養 / カロテノイド / 海洋細菌
Outline of Final Research Achievements

In this study, we searched for unknown functional rhodopsin in eukaryotic microorganisms and giant viruses, as well as bacteria, by collecting and analyzing data on genomes, metagenomes and transcriptomes of microorganisms. As a result, we succeeded in discovering several unknown rhodopsins and clarifying their functions. Furthermore, the molecular phylogeny and distribution of rhodopsin genes were visualized on a large scale. We also demonstrated the possibility of an unknown retinal biosynthetic pathway using a bacterial isolate that possesses the rhodopsin gene but not the gene for the retinal biosynthetic pathway.

Academic Significance and Societal Importance of the Research Achievements

地球上に生息するほぼ全ての生物は太陽光に由来するエネルギーを使って生命活動を行なっている。一般的に、太陽光を生態系に流す窓口になる生物は光合成システムを保有し酸素発生型光合成を行う生物である。しかしながら、2000年に海洋微生物から微生物型ロドプシンが発見され、これまで光を全く受容しないと考えられていた微生物も太陽光を利用していることが示された。本研究では、ロドプシ遺伝子の探索および機能解析対象をバクテリアだけでなく真核微生物や巨大ウイルスまで拡張することで、生態系における光エネルギー利用の概念に新たな1ページを書き加えた。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (36 results)

All 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (2 results) Journal Article (13 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 13 results,  Open Access: 11 results) Presentation (19 results) (of which Int'l Joint Research: 5 results,  Invited: 8 results) Remarks (2 results)

  • [Int'l Joint Research] Stanford University/University of Hawaii/Monterey Bay Aquarium Research Institute(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] The Chinese University of Hong Kong(中国)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.2022

    • Author(s)
      Hosaka, T. et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 119 Issue: 9

    • DOI

      10.1073/pnas.2117433119

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diversity and Composition of Microbial Communities in an Eelgrass (<i>Zostera marina</i>) Bed in Tokyo Bay, Japan2021

    • Author(s)
      Iqbal Md Mehedi、Nishimura Masahiko、Haider Md. Nurul、Sano Masayoshi、Ijichi Minoru、Kogure Kazuhiro、Yoshizawa Susumu
    • Journal Title

      Microbes and Environments

      Volume: 36 Issue: 4 Pages: n/a

    • DOI

      10.1264/jsme2.ME21037

    • NAID

      130008103593

    • ISSN
      1342-6311, 1347-4405
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Functional expression of the eukaryotic proton pump rhodopsin OmR2 in Escherichia coli and its photochemical characterization2021

    • Author(s)
      Kikuchi Masuzu、Kojima Keiichi、Nakao Shin、Yoshizawa Susumu、Kawanishi Shiho、Shibukawa Atsushi、Kikukawa Takashi、Sudo Yuki
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 14765-14765

    • DOI

      10.1038/s41598-021-94181-w

    • NAID

      120007147387

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A unique clade of light-driven proton-pumping rhodopsins evolved in the cyanobacterial lineage2020

    • Author(s)
      Hasegawa Masumi、Hosaka Toshiaki、Kojima Keiichi、Nishimura Yosuke、Nakajima Yu、Kimura-Someya Tomomi、Shirouzu Mikako、Sudo Yuki、Yoshizawa Susumu
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 16752-16752

    • DOI

      10.1038/s41598-020-73606-y

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bacterium Lacking a Known Gene for Retinal Biosynthesis Constructs Functional Rhodopsins2020

    • Author(s)
      Nakajima Yu、Kojima Keiichi、Kashiyama Yuichiro、Doi Satoko、Nakai Ryosuke、Sudo Yuki、Kogure Kazuhiro、Yoshizawa Susumu
    • Journal Title

      Microbes and Environments

      Volume: 35 Issue: 4 Pages: n/a-n/a

    • DOI

      10.1264/jsme2.me20085

    • NAID

      130007950468

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lokiarchaeota archaeon schizorhodopsin-2 (LaSzR2) is an inward proton pump displaying a characteristic feature of acid-induced spectral blue-shift2020

    • Author(s)
      Kojima Keiichi、Yoshizawa Susumu、Hasegawa Masumi、Nakama Masaki、Kurihara Marie、Kikukawa Takashi、Sudo Yuki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 20857-20857

    • DOI

      10.1038/s41598-020-77936-9

    • NAID

      120006955824

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Vectorial Proton Transport Mechanism of RxR, a Phylogenetically Distinct and Thermally Stable Microbial Rhodopsin2020

    • Author(s)
      Kojima Keiichi、Ueta Tetsuya、Noji Tomoyasu、Saito Keisuke、Kanehara Kanae、Yoshizawa Susumu、Ishikita Hiroshi、Sudo Yuki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-019-57122-2

    • NAID

      120006884916

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators2019

    • Author(s)
      Needham David M.、Yoshizawa Susumu、Hosaka Toshiaki et. al.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 41 Pages: 20574-20583

    • DOI

      10.1073/pnas.1907517116

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cortical layer?specific critical dynamics triggering perception2019

    • Author(s)
      Marshel James H.、Kim Yoon Seok、Machado Timothy A.、Quirin Sean、Benson Brandon、Kadmon Jonathan、Raja Cephra、Chibukhchyan Adelaida、Ramakrishnan Charu、Inoue Masatoshi、Shane Janelle C.、McKnight Douglas J.、Yoshizawa Susumu、Kato Hideaki E.、Ganguli Surya、Deisseroth Karl
    • Journal Title

      Science

      Volume: 365 Issue: 6453

    • DOI

      10.1126/science.aaw5202

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Photochemical Characterization of a New Heliorhodopsin from the Gram-Negative Eubacterium Bellilinea caldifistulae (BcHeR) and Comparison with Heliorhodopsin-48C122019

    • Author(s)
      Shibukawa A, Kojima K, Nakajima Y, Nishimura Y, Yoshizawa S, Sudo Y
    • Journal Title

      Biochemistry

      Volume: 58(26) Issue: 26 Pages: 2934-2943

    • DOI

      10.1021/acs.biochem.9b00257

    • NAID

      120006847070

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Repeated Evolutionary Transitions of Flavobacteria from Marine to Non‐Marine Habitats2019

    • Author(s)
      Hao Zhang, Susumu Yoshizawa, Ying Sun, Yongjie Huang, Xiao Chu, Jose M. Gonzalez, Jarone Pinhassi, Haiwei Luo
    • Journal Title

      Environmental Microbiology

      Volume: 21 Issue: 2 Pages: 648-666

    • DOI

      10.1111/1462-2920.14509

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Amylibacter kogurei sp. nov., a novel marine alphaproteobacterium isolated from the coastal sea surface microlayer of a marine inlet2018

    • Author(s)
      Wong Shu-Kuan、Yoshizawa Susumu、Nakajima Yu、Cuadra Marie Johanna、Nogi Yuichi、Nakamura Keiji、Takami Hideto、Ogura Yoshitoshi、Hayashi Tetsuya、Chiura Hiroshi Xavier、Hamasaki Koji
    • Journal Title

      International Journal of Systematic and Evolutionary Microbiology

      Volume: 68 Issue: 9 Pages: 2872-2877

    • DOI

      10.1099/ijsem.0.002911

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Draft Genome Sequence of Saccharospirillum sp. Strain MSK14-1, Isolated from Surface Seawater Collected at Aburatsubo Inlet in Japan2018

    • Author(s)
      5.Masumi Hasegawa, Yu Nakajima, Shu-Kuan Wong, Keiji Nakamura, Yoshitoshi Ogura, Tetsuya Hayashi, Kazuhiro Kogure and Susumu Yoshizawa
    • Journal Title

      Genome announcements

      Volume: 6 Issue: 22

    • DOI

      10.1128/genomea.00469-18

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 微生物と光の関係を紐解く!2021

    • Author(s)
      吉澤晋
    • Organizer
      「第七回極低放射能技術」研究会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 海洋性細菌のCl-ポンプロドプシンにおける波長制御メカニズムの変異体解析2020

    • Author(s)
      永田崇、烏山昌幸、中島悠、吉澤晋、竹内一郎、井上圭一
    • Organizer
      日本生体エネルギー研究会第46回討論会
    • Related Report
      2020 Annual Research Report
  • [Presentation] シアノバクテリアの光合成とは異なる光利用:シアノロドプシンの発見2020

    • Author(s)
      長谷川万純、保坂俊彰、小島慧一、西村陽介、中島 悠、染谷友美、 白水美香子、須藤雄気、吉澤晋
    • Organizer
      日本地球化学会第67回年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Host leaf age shapes the phyllosphere microbiomes of eelgrass (Zostera marina)2020

    • Author(s)
      Rocky Md. Mehedi Iqbal, Nishimura Masahiko and Yoshizawa Susumu
    • Organizer
      ISME virtual microbial ecology summit
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Marine biodiversity: Light utilization of microbes & eDNA researchUTokyo2019

    • Author(s)
      Susumu Yoshizawa
    • Organizer
      NTU Joint Conference 2019 --Co-creating the Future Society in Asia--
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Microbial rhodopsin: a photoreceptor protein found in all environments where light reaches, and water is present2019

    • Author(s)
      Susumu Yoshizawa
    • Organizer
      The 3rd Joint Symposium on Integrated Biosciences between Zhejiang University and the University of Tokyo
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 光シグナルを出す?見る?利用する?2019

    • Author(s)
      吉澤 晋
    • Organizer
      共生起源研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] メタゲノム中のダークマター機能性遺伝子の解析2019

    • Author(s)
      吉澤晋, 西村陽介, 岩崎渉
    • Organizer
      第32回日本微生物生態学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 光を使うか、それとも避けるか? ―海洋細菌の二種類の光適応戦略の解明2019

    • Author(s)
      熊谷洋平, 吉澤晋, 木暮一啓, 岩崎渉
    • Organizer
      第32回日本微生物生態学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 網羅的なロドプシン系統解析から理解する微生物の進化と生態2019

    • Author(s)
      西村 陽介, 吉澤 晋
    • Organizer
      第32回日本微生物生態学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 色と遺伝子で紐解く微生物の光コミュニケーション2019

    • Author(s)
      吉澤晋
    • Organizer
      第2回若手シンポジウム(新学術領域研究「化学コミュニケーションのフロンティア」)
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Light-adaptation strategies of marine Flavobacteria2018

    • Author(s)
      Susumu Yoshizawa, Yohei Kumagai, Kazuhiro Kogure and Wataru Iwasaki
    • Organizer
      1st International Conference on Marine Flavobacteria
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A haloarchaeal halorhodopsin-Like Cl- Pump in Marine Bacteria2018

    • Author(s)
      Susumu Yoshizawa, Yu Nakajima and Kazuhiro Kogure
    • Organizer
      17th International Society for Microbial Ecology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] To use light or to avoid it? Light-adaptation strategies in marine bacteria2018

    • Author(s)
      Susumu Yoshizawa
    • Organizer
      第56回日本生物物理学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] レチナール生産遺伝子(blh)はロドプシン保有細菌に必須か?2018

    • Author(s)
      中島悠, 土井聡子, 小島慧一, 須藤雄気, 木暮一啓, 吉澤晋
    • Organizer
      第32回日本微生物生態学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ロドプシンが織りなす“複雑なタペストリー”2018

    • Author(s)
      吉澤晋
    • Organizer
      第25回日本微生物資源学会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ロドプシン保持細菌の例から考える、光従属栄養性のメリットとデメリット2018

    • Author(s)
      吉澤晋
    • Organizer
      2018年度第3回光合成細菌ワークショップ
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 光を使うか、それとも避けるか?海洋性フラボバクテリアの光適応戦略2018

    • Author(s)
      Susumu Yoshizawa, Yohei Kumagai, Kazuhiro Kogure and Wataru Iwasaki
    • Organizer
      第32回日本微生物生態学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Physiological roles of synechocystis halorhodopsin (SyHR) in freshwater cyanobacteria2018

    • Author(s)
      Masumi Hasegawa, Kaisei Maeda, Masahiko Ikeuchi, Susumu Yoshizawa
    • Organizer
      第32回日本微生物生態学会
    • Related Report
      2018 Annual Research Report
  • [Remarks] 光でイオンを輸送する膜タンパク質の巧妙な仕組み

    • URL

      https://www.aori.u-tokyo.ac.jp/research/news/2022/20220228.html

    • Related Report
      2021 Annual Research Report
  • [Remarks] 光合成微生物“シアノバクテリア”の新たな光エネルギー利用機構 ーシアノロドプシンの発見ー

    • URL

      https://www.aori.u-tokyo.ac.jp/research/topics/2020/20201030.html

    • Related Report
      2020 Annual Research Report

URL: 

Published: 2018-04-23   Modified: 2023-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi