| Project/Area Number |
18H06385
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Review Section |
0908:Society medicine, nursing, and related fields
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| Research Institution | Hokkaido University |
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Principal Investigator |
Lee Hyojung 北海道大学, 医学研究院, 助教 (40823365)
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| Project Period (FY) |
2018-08-24 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | Ebola virus disease / Recurrence / Generation time / Extinction / Sexual transmission / Epidemic / Zika virus / Modeling |
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| Outline of Annual Research Achievements |
The proposed research project aims to quantify the relative contributions of asymptomatic infection and of sexual transmission compared with other routes of transmission to secondary transmission event of Ebola virus disease (EVD) using epidemiological modelling approaches. The criteria of zero Ebola cases defined by the World Health Organization did not explicitly account for the sexual transmission and led to multiple recrudescent events in West Africa from 2015-2016, partly indeed caused by sexual transmission. We proposed a statistical model to compute the probability of the end of an EVD epidemic, accounting for sexual transmission and under-ascertainment of cases. Analyzing the data in Guinea, Liberia and Sierra Leone, we objectively offers the end of an epidemic.
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| Research Progress Status |
平成30年度が最終年度であるため、記入しない。
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| Strategy for Future Research Activity |
平成30年度が最終年度であるため、記入しない。
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