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ジョーンズ行列型光コヒーレンスエラストグラフィー法の確立と皮膚科学への応用

Research Project

Project/Area Number 18J13841
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeSingle-year Grants
Section国内
Research Field Optical engineering, Photon science
Research InstitutionUniversity of Tsukuba

Principal Investigator

李 恩  筑波大学, 数理物質科学研究科, 特別研究員(DC2)

Project Period (FY) 2018-04-25 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2019: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2018: ¥800,000 (Direct Cost: ¥800,000)
KeywordsOCT / JM-OCE / birefringence / displacement / deformation / polarization / biomechanics / biomechanical properties / decorrelation map
Outline of Annual Research Achievements

The active compression based Jones matrix optical coherence elastography (JM-OCE) has been established. The hardware of the system and its post-processing method has been upgraded and modified, such that the imaging depth range has been enlarged and the quality and accuracy of local birefringence imaging for tissues has been improved.Finally, the simultaneous imaging of intensity OCT, local birefringence, in-plane lateral and axial displacement, microstructural decorrelation / deformation (MSD) for biological tissues has been demonstrated. The results indicate that JM-OCE would provide more comprehensive information for biological tissue investigation.

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (9 results)

All 2020 2019 2018

All Journal Article (4 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (5 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography2020

    • Author(s)
      Miyazawa Arata、Makita Shuichi、Li En、Yamazaki Kohei、Kobayashi Masaki、Sakai Shingo、Yasuno Yoshiaki
    • Journal Title

      Proc. SPIE

      Volume: 11242 Pages: 1124214-1124214

    • DOI

      10.1117/12.2544687

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Depth-Resolved Investigation of Multiple Optical Properties and Wrinkle Morphology in Eye-Corner Area by Multi-Functional Jones Matrix Optical Coherence Tomography2020

    • Author(s)
      Yamazaki, Kohei, En Li, Arata Miyazawa, Masaki Kobayashi, Tetsuya Sayo, Shuichi Makita, Yoshito Takahashi, Yoshiaki Yasuno, and Shingo Sakai
    • Journal Title

      Proc. SPIE

      Volume: 11211 Pages: 1-6

    • DOI

      10.1117/12.2543977

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Polarization-Sensitive Optical Coherence Elastography2019

    • Author(s)
      Miyazawa, Arata, Shuichi Makita, En Li, Kohei Yamazaki, Masaki Kobayashi, Shingo Sakai, and Yoshiaki Yasuno
    • Journal Title

      Biomedical Optics Express

      Volume: 10 Issue: 10 Pages: 5162-5181

    • DOI

      10.1364/boe.10.005162

    • NAID

      120007127626

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Compression optical coherence elastography with two-dimensional displacement measurement and local deformation visualization2019

    • Author(s)
      Li En、Makita Shuichi、Azuma Shinnosuke、Miyazawa Arata、Yasuno Yoshiaki
    • Journal Title

      Optics Letters

      Volume: 44 Issue: 4 Pages: 787-787

    • DOI

      10.1364/ol.44.000787

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography2020

    • Author(s)
      Miyazawa Arata
    • Organizer
      SPIE Photonics West (BiOS) 2020
    • Related Report
      2019 Annual Research Report
  • [Presentation] Depth-resolved investigation of multiple optical properties and wrinkle morphology in eye-corner area by multi-functional Jones matrix optical coherence tomography2020

    • Author(s)
      Yamazaki Kohei
    • Organizer
      SPIE Photonics West (BiOS) 2020
    • Related Report
      2019 Annual Research Report
  • [Presentation] Simultaneous analysis of optical and biomechanical properties of tissue by compression-based polarization sensitive optical coherence elastography2019

    • Author(s)
      En Li, Shuichi Makita, Arata Miyazawa, Shinnosuke Azuma, Yoshiaki Yasuno
    • Organizer
      SPIE Photonics West 2019 (BiOS)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Lateral and axial displacements and microstructural decorrelation measurement for compression-based optical coherence elastography2019

    • Author(s)
      En Li, Shuichi Makita, Arata Miyazawa, Shinnosuke Azuma, Yoshiaki Yasuno
    • Organizer
      SPIE Photonics West 2019 (BiOS)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Simultaneous imaging of scleral birefringence and biomechanics by Jones matrix optical coherence elastography2018

    • Author(s)
      En Li, Yuta Ueno, Shuichi Makita, Tetsuro Oshika, Yoshiaki Yasuno
    • Organizer
      2018 ARVO Imaging in the Eye Conference
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research

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Published: 2018-05-01   Modified: 2024-03-26  

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