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Elucidation of the neuronal mechanism of experience-dependent plasticity in the acoustic behavior

Research Project

Project/Area Number 18J15228
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeSingle-year Grants
Section国内
Research Field Neurophysiology / General neuroscience
Research InstitutionNagoya University

Principal Investigator

LI XIAODONG  名古屋大学, 理学研究科, 特別研究員(PD)

Project Period (FY) 2018-04-25 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,000,000 (Direct Cost: ¥1,000,000)
Keywordssong preference / innate / experience-dependent / plasticity / auditory experience / mating preference
Outline of Annual Research Achievements

Sound preference is the foundation of auditory learning, as when songbirds acquire song and humans acquire language. However, the mechanisms by which animals that rely on auditory learning for acoustic communication form sound preference remain elusive. Here we propose the use of Drosophila as a simple model to study these underlying neural mechanisms by addressing three major aspects in forming auditory preference. Firstly, flies exhibit innately higher auditory responses to conspecific songs than to heterospecific songs. Secondly, flies cannot sustain song preference during song deprivation or social isolation. Thirdly, flies selectively learn from song experience to prevent the loss of innate preference.

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (11 results)

All 2018 Other

All Journal Article (3 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (3 results) (of which Int'l Joint Research: 1 results) Remarks (5 results)

  • [Journal Article] Auditory experience controls the maturation of song discrimination and sexual response in Drosophila2018

    • Author(s)
      Xiaodong Li, Hiroshi Ishimoto, Azusa Kamikouchi
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.34348

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Assessing Experience-dependent Tuning of Song Preference in Fruit Flies (Drosophila melanogaster)2018

    • Author(s)
      Li Xiaodong、Ishimoto Hiroshi、Kamikouchi Azusa
    • Journal Title

      BIO-PROTOCOL

      Volume: 8 Issue: 14

    • DOI

      10.21769/bioprotoc.2932

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] GABAergic local interneurons shape female fruit fly response to mating songs2018

    • Author(s)
      Daichi Yamada, Hiroshi Ishimoto, Xiaodong Li, Tsunehiko Kohashi, Yuki Ishikawa, Azusa Kamikouchi
    • Journal Title

      The Journal of Neuroscience

      Volume: 印刷中 Issue: 18 Pages: 4329-4347

    • DOI

      10.1523/jneurosci.3644-17.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Mechanisms of auditory learning behavior in fruit flies2018

    • Author(s)
      Xiaodong Li
    • Organizer
      The 83th Cold Spring Harbor Laboratory Symposium, Order & Disorder in the Nervous System
    • Related Report
      2018 Annual Research Report
  • [Presentation] Auditory experience modulates song preference and mating choice in Drosophila2018

    • Author(s)
      Xiaodong Li
    • Organizer
      Cold Spring Harbor Asia meeting on Latest Advances in Development & Function of Neuronal Circuits
    • Related Report
      2018 Annual Research Report
  • [Presentation] Auditory experience tunes song preference in Drosophila2018

    • Author(s)
      Xiaodong Li
    • Organizer
      The 48th annual meeting of American Society for Neuroscience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Remarks] ハエ羽音の歌学習

    • URL

      http://www.bio.nagoya-u.ac.jp/files/topics/180323.html

    • Related Report
      2018 Annual Research Report
  • [Remarks] ハエだって聞きなれた歌が好き

    • URL

      http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20180320_sci_1.pdf

    • Related Report
      2018 Annual Research Report
  • [Remarks] ハエは「求愛歌」をどうやって聞き分けるのか 名古屋大学の研究

    • URL

      https://www.zaikei.co.jp/article/20180326/433688.html

    • Related Report
      2018 Annual Research Report
  • [Remarks] Even flies like a familiar song

    • URL

      https://www.sciencedaily.com/releases/2018/03/180320100850.htm

    • Related Report
      2018 Annual Research Report
  • [Remarks] How auditory learning shapes fly behavior

    • URL

      https://www.researchsea.com/html/article.php/aid/11548/cid/1/research/science/nagoya_university/even_flies_like_a_familiar_song__how_auditory_learning_shapes_fly_behavior.html

    • Related Report
      2018 Annual Research Report

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Published: 2018-05-01   Modified: 2024-03-26  

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