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発達性協調運動障害と自閉症スペクトラム障害における不器用さの特徴とメカニズム解明

Research Project

Project/Area Number 18J23420
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeSingle-year Grants
Section国内
Research Field Special needs education
Research InstitutionHirosaki University

Principal Investigator

三上 美咲  弘前大学, 保健学研究科, 特別研究員(DC1)

Project Period (FY) 2018-04-25 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2020: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2019: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2018: ¥800,000 (Direct Cost: ¥800,000)
Keywords発達性協調運動障害 / 発達障害 / 協調運動
Outline of Annual Research Achievements

協調運動の特徴については、データの蓄積が完了した158名について、手部の総移動距離等の算出および特徴の抽出を行なった結果、DCDやASDを含む微細運動の問題を持つ発達障害児は、スピードを求められる微細運動において、手部を必要以上に多く動かすこと、特に小さな的に合わせて手部の位置を調整することに時間と運動量を要すという特徴を持つことが明らかになった。また、筆記具操作方法については、対象児225名について発達障害による影響を含め検討した。DCDやASD児において知的障害を伴わない場合は、診断のない児に比べた筆記具操作方法の遅れは認めらなかった。知的な遅れに伴う場合には有意な遅れが認められ、筆記具操作の発達には知的発達の影響が大きいことが確認された。
協調運動の問題に影響する因子としての感覚処理特性について、協調運動能力との関連を検討した。DCD児63名における重回帰分析の結果、粗大運動への感覚回避傾向、視覚の問題の関連、微細運動への感覚過敏傾向、聴覚の問題の関連が認められた。昨年度の結果も踏まえ、DCD児の病態への感覚処理特性の関与が強調され、DCD児への支援や介入を行う際には彼らの感覚処理特性を評価することの重要性が示唆された。
DCD児の支援へと役立てるための行動面や情緒面の困難の検討については、5歳児健診時点と小学校3年生までの4時点でのSDQのデータを用い、Latent class growth analysis(LCGA)による縦断解析を行なった。結果、SDQ合計得点は4つのパターンに分かれ変化することが示された。また、5歳でカットオフ値以上の行動および情緒的問題を示したDCD児の約半数は、就学後もその問題を持ち続け、さらに悪化傾向を示すことが明らかになった。これらのことから、行動および情緒的問題を持つDCD児への修学前後の早期介入の必要性が示唆された。

Research Progress Status

令和2年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和2年度が最終年度であるため、記入しない。

Report

(3 results)
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (41 results)

All 2021 2020 2019 2018

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (39 results) (of which Int'l Joint Research: 14 results)

  • [Journal Article] Atypical Sensory Processing Profiles and Their Associations With Motor Problems In Preschoolers With Developmental Coordination Disorder2020

    • Author(s)
      Mikami Misaki、Hirota Tomoya、Takahashi Michio、Adachi Masaki、Saito Manabu、Koeda Shuhei、Yoshida Kazutaka、Sakamoto Yui、Kato Sumi、Nakamura Kazuhiko、Yamada Junko
    • Journal Title

      Child Psychiatry & Human Development

      Volume: 52 Issue: 2 Pages: 311-320

    • DOI

      10.1007/s10578-020-01013-5

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats2020

    • Author(s)
      Chihiro Sato, Kunikazu Tanji, Shuji Shimoyama, Mitsuru Chiba, Misaki Mikami, Shuhei Koeda, Koshi Sumigawa,Kazuki Akahira, Junko Yamada
    • Journal Title

      Neuroreport

      Volume: 31 Issue: 2 Pages: 189-195

    • DOI

      10.1097/wnr.0000000000001396

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 発達性協調運動障害を持つ幼児の感覚処理の問題と協調運動機能との関連2021

    • Author(s)
      三上美咲・廣田智也・高橋芳雄・足立匡基・斉藤まなぶ・小枝周平・中村和彦・山田順子
    • Organizer
      第4回日本DCD学会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] The motor recovery and synaptic plasticity was affected by the types of exercise in the hemorrhage model rat2021

    • Author(s)
      Chihiro Sato, Kunikazu Tanji, Koeda Suhei, Mana Kishimoto, Shun Mori, Misaki Mikami, Junko Yamada
    • Organizer
      The 98th Annual Meeting of The Physiological Society of Japan, the 126th Annual Meeting of The Japanese Association of Anatomists
    • Related Report
      2020 Annual Research Report
  • [Presentation] 運動嫌いにより介入が困難であった発達性協調運動障害の一症例2021

    • Author(s)
      小枝周平・三上美咲・斉藤まなぶ・佐藤ちひろ・富田桃子・中村和彦・山田順子
    • Organizer
      第4回日本DCD学会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Forced exercise causes the negative emotional and behavioral changes to the mouse model of autism spectrum disorder2021

    • Author(s)
      Shuhei Koeda, Ayaka Monden, Misaki Mikami, Chihiro Sato, Junko Yamada
    • Organizer
      The 44th Annual Meeting of the Japan Neuroscience Society
    • Related Report
      2020 Annual Research Report
  • [Presentation] Early detection of ASD by community-based screening focusing on sensory processing characteristics. Poster presentation2021

    • Author(s)
      Masaki Adachi, Michio Takahashi, Hirota Tomoya, Misaki Mikami, Hiroki Shinkawa, Hiroyuki Mori, Manabu Saito, Taku Hagiwara, Kazuhiko Nakamura
    • Organizer
      International Society for Autism Research (INSAR) Annual meeting 2021
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 幼児期における発達障害児の筆記具操作と描線運動2020

    • Author(s)
      三上美咲・小枝周平・斉藤まなぶ・中村和彦・山田順子
    • Organizer
      第54回日本作業療法学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] The developmental trajectories of social-emotional-behavioral challenges in children with developmental coordination2020

    • Author(s)
      Misaki Mikami
    • Organizer
      24th World Congress of the International Association for Child and Adolescent Psychiatry and Allied Professions' (IACAPAP) 2020
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Sensory processing abnormalities and their associations with behavioral and emotional difficulties in preschoolers with Developmental Coordination Disorder.2020

    • Author(s)
      Misaki Mikami, Masaki Adachi, Michio Takahashi, Tomoya Hirota, Manabu Saito, Shuhei Koeda, Kazutaka Yoshida, Kazuhiko Nakamura, Junko Yamada
    • Organizer
      24th World Congress of the International Association for Child and Adolescent Psychiatry and Allied Professions' (IACAPAP) 2020
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The motor recovery synaptic plasticity after stroke were affected by the types of exercise2020

    • Author(s)
      Chihiro Sato, Kunikazu Tanji, Mitsuru Chiba, Misaki Mikami, Junko Yamada.
    • Organizer
      The 43th Annual Meeting of the Japan Neuroscience Society
    • Related Report
      2020 Annual Research Report
  • [Presentation] 日本人の自閉症児における栄養と食物摂取2020

    • Author(s)
      小枝周平・三上美咲・斉藤まなぶ・中村和彦・山田順子
    • Organizer
      第54回日本作業療法学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 脳出血モデルラットにおける運動種類の違いが運動麻痺回復および脳可塑性関連因子に及ぼす影響2020

    • Author(s)
      佐藤ちひろ・小枝周平・三上美咲・山田順子
    • Organizer
      第54回日本作業療法学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 脳出血ラットにおける運動種類の違いが機能回復に与える影響2020

    • Author(s)
      佐藤ちひろ・小枝周平・三上美咲・山田順子
    • Organizer
      第52回東北生理談話会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Characteristics of fine motor performance and factors associated with motor problems in preschoolers with developmental coordination disorders.2020

    • Author(s)
      Mikami Misaki, Koeda Shuhei, Saito Manabu, Osato Ayako, Masuda Takahito, Sato Chihiro, Nakamura Kazuhiko, Yamada Junko
    • Organizer
      The 97th Annual Meeting of the Physiological Society of Japan.
    • Related Report
      2019 Annual Research Report
  • [Presentation] 脳出血モデルラットにおける異なる種類の運動が機能回復に与える影響2020

    • Author(s)
      佐藤 ちひろ・小枝 周平・三上 美咲・赤平一樹・山田 順子
    • Organizer
      第157回弘前医学会例会
    • Related Report
      2019 Annual Research Report
  • [Presentation] The nutrition and food intake of Japanese 5-years autism spectrum disorder children.2020

    • Author(s)
      Koeda Shuhei, Akiyama Kanae, Saito Manabu, Mikami Misaki, Mikami Tamaki, Sato Chihiro, Nakamura Kazuhiko, Junko Yamada
    • Organizer
      The 97th Annual Meeting of the Physiological Society of Japan.
    • Related Report
      2019 Annual Research Report
  • [Presentation] 5歳における発達性協調運動障害児の筋力2019

    • Author(s)
      三上美咲・斉藤まなぶ・小枝周平・大里絢子・増田貴人・中村和彦・山田順子
    • Organizer
      第3回日本DCD学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 第10回東北精神保健福祉学会秋田大会2019

    • Author(s)
      三上美咲・斉藤まなぶ・小枝周平・大里絢子・増田貴仁・中村和彦・山田順子
    • Organizer
      発達性協調運動障害を持つ幼児の行動及び情緒的問題
    • Related Report
      2019 Annual Research Report
  • [Presentation] Characteristics of developmental coordination disorders for fine motor skill in 5-year-old children: A 2D video tracking analysis system.2019

    • Author(s)
      Misaki Mikami, Manabu Saito, Shuhei Koeda, Ayako Osato, Takahito Masuda, Kazuhiko Nakamura, Junko Yamada
    • Organizer
      13th Developmental Coordination Disorder Conference (DCD13)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 定型発達児の線切り課題におけるハサミの使用方法とはみ出し幅2019

    • Author(s)
      小枝周平・三上美咲・奈良岡碧・富田桃子・佐藤ちひろ・山田順子
    • Organizer
      第3回日本DCD学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] PIT法を用いた脳梗塞ラットにおける麻痺側肢集中使用が運動機能回復に及ぼす影響2019

    • Author(s)
      赤平一樹・佐藤ちひろ・三上美咲・山田順子
    • Organizer
      第53回日本作業療法学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 就学前の発達性協調運動障害(DCD)早期発見のためのDCDQ短縮版作成の試み ~顕在化しにくい発達障害を早期に抽出するアセスメントツールの開発研究から~2019

    • Author(s)
      斉藤まなぶ・三上美咲・北洋輔・大里絢子・小枝周平・三上珠希・稲垣真澄・中村和彦
    • Organizer
      第10回東北精神保健福祉学会秋田大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 就学前の発達性協調運動障害(DCD)早期発見のためのチェックリストと活用マニュアルの完成 ~顕在化しにくい発達障害を早期に抽出するアセスメントツールの開発研究から~2019

    • Author(s)
      斉藤まなぶ・北洋輔・大里絢子・三上美咲・小枝周平・三上珠希・稲垣真澄・中村和彦
    • Organizer
      第60回日本児童青年精神医学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] The comparison of the synaptic changes with voluntary and forced rehabilitation in intracerebral hemorrhage model rats.2019

    • Author(s)
      Chihiro Sato, Kunikazu Tanji,Shuji Shimoyama, Misaki Mikami, Kazuki Akahira, Junko Yamada.
    • Organizer
      The 1st Japan-Korea-Taiwan Neurorehabilitation Conference.
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effects of sensory and cognitive functions on motor coordination functions in 5-years old children.2019

    • Author(s)
      Ayako Osato, Manabu Saito, Misaki Mikami, Shuhei Koeda, Junko Yamada, Takahito Masuda, Kazuhiko Nakamura.
    • Organizer
      13th Developmental Coordination Disorder Conference (DCD13).
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Characteristics of eye movements of children with developmental cooperative movement disorder.2019

    • Author(s)
      Manabu Saito, Taiahiro Aoki, Shuhei Koeda, Misaki Mikami, Kazutaka Yoshida, Ayako Kaneda-Osato, Takahito Masuda, Yui Sakamoto, Tamaki Mikami, Kenji Tsuchiya, Taiichi Katayama, Kazuhiko Nakamura.
    • Organizer
      13th Developmental Coordination Disorder Conference (DCD13)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Features of fine motor skills in 5-year-old children with developmental coordination disorders2019

    • Author(s)
      Misaki Mikami, Shuhei Koeda, Ayako Osato, Takahito Masuda, Manabu Saito, Kazuhiko Nakamura, Junko Yamada
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effects of sensory and cognitive functions on motor coordination in 5-years old children2019

    • Author(s)
      Ayako Osato, Misaki Mikami, Manabu Saito, Shuhei Koeda, Tamaki Mikami, Yui Sakamoto, Kazutaka Yoshida, Yuri Matsubara, Junko Yamada, Kazuhiko Nakamura
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Nutritional status of Japanese children with developmental disorders2019

    • Author(s)
      Shuhei Koeda, Misaki Mikami, Manabu Saito, Tamaki Mikami, Kazuhiko Nakamura, Junko Yamada
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Characteristics of Eye Movements of 5-year-old Children with Developmental Coordination Disorder2019

    • Author(s)
      Manabu Saito, Shuhei Koeda, Misaki Mikami, Taiahiro Aoki, Kazutaka Yoshida, Yui Sakamoto, Junko Yamada, Kenji Tsuchiya, Taiichi Katayama, Kazuhiko Nakamura
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Voluntary and forced rehabilitation to promote motor palsy recovery in intracerebral hemorrhage rats2019

    • Author(s)
      Chihiro Sato, Kunikazu Tanji, Shuji Shimoyama, Misaki Mikami, Kazuki Akahira, Junko Yamada
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of forced limb training of rats under photochemically induced focal cerebral ischemia2019

    • Author(s)
      Junko Yamada, Kazuki Akahira, Misaki Mikami, Yuuri Kato, Chihiro Sato
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 5歳児における協調運動機能へ影響を及ぼす感覚及び認知的因子2018

    • Author(s)
      三上美咲、山本千夏、斉藤まなぶ、小枝周平、中村和彦、山田順子
    • Organizer
      第2回日本DCD学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 脳出血ラットにおける運動に伴うモチベーション有無が麻痺回復効果に及ぼす影響2018

    • Author(s)
      佐藤 ちひろ、赤平 一樹、澄川 幸志、小枝 周平、三上 美咲、山田 順子
    • Organizer
      第9回ニューロリハビリテーション学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] PIT法を用いた脳梗塞ラットにおける麻痺側肢集中使用後の機能回復効果2018

    • Author(s)
      赤平一樹、佐藤ちひろ、三上美咲、山田順子
    • Organizer
      第9回ニューロリハビリテーション学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] The effect of the voluntary exercises as a reward behavior for stroke rat2018

    • Author(s)
      Chihiro Sato, Kazuki Akahira, Shuhei Koeda, Koshi Sumigawa, Misaki Mikami, Junko Yamada
    • Organizer
      第41回日本神経科学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 幼児期における協調運動の問題への感覚機能および認知機能の影響2018

    • Author(s)
      三上美咲、斉藤まなぶ、小枝周平、中村和彦、山田順子
    • Organizer
      第 52 回日本作業療法学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] PIT法を用いた脳梗塞ラットにおける麻痺側肢集中使用が運動機能回復に及ぼす影響2018

    • Author(s)
      赤平一樹、佐藤ちひろ、三上美咲、山田順子
    • Organizer
      第52回日本作業療法学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 5歳児における協調運動機能へ影響を及ぼす認知及び感覚的因子2018

    • Author(s)
      大里絢子、三上美咲、斉藤まなぶ、坂本由唯、足立匡基、安田小響、増田貴人、田中勝則、栗林理人、中村和彦
    • Organizer
      第59回日本児童青年精神医学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] The effect of the forced limb using training for recovery of the motor paralysis in cerebral ischemic model rat by photochemically induced thrombosis (PIT).2018

    • Author(s)
      Chihiro Sato, Kazuki Akahira, Shuhei Koeda, Koshi Sumigawa, Misaki Mikami, Junko Yamada
    • Organizer
      48th Annual meeting of Society for Neuroscience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research

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Published: 2018-05-01   Modified: 2024-03-26  

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