Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Outline of Final Research Achievements |
This study demonstrated that dietary fat types influenced the effects of dietary nondigestible oligosaccharides on the colonic luminal environment, including ALP activity. The effect of oligosaccharides on colonic ALP activity and luminal variables was prominent when the rats are fed lard diet compared to rats fed soybean oil diet, or corn oil diet. It was further found that the inductive effect of dietary oligosaccharides on colonic ALP activity was prominent under the high-fat diet or high-protein diet conditions. These results suggest that nutritional conditions such as the quality or quantity of dietary fat or protein may change the effects of nondigestible carbohydrates on the colonic luminal environment including the ALP activity.
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