Problem of coexisting bipolarity and ADHD in childhood and adolescence

• Project/Area Number: 18K03129
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 10030:Clinical psychology-related
• Research Institution: Chiba University
• Principal Investigator: TANAKA Mami 千葉大学, 社会精神保健教育研究センター, 特任講師 (90600198)
• Co-Investigator(Kenkyū-buntansha): 橋本 謙二 千葉大学, 社会精神保健教育研究センター, 教授 (10189483)
• Project Period (FY): 2018-04-01 – 2022-03-31
• Project Status: Discontinued (Fiscal Year 2021)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 双極性障害傾向 / ADHD / 児童期 / 思春期

Outline of Final Research Achievements

This study aimed to elucidate the psychological factors associated with bipolarity in childhood and adolescence, including the issue of comorbidity with attention-deficit/hyperactivity disorder (ADHD). The results found that there were differences in the association between bipolarity and the subdimension of self-regulation depending on whether the child met the assessment criteria for ADHD and various effects on the relation between maternal mental health and the child’s bipolarity.

Academic Significance and Societal Importance of the Research Achievements

双極性障害は，単極性のうつ病・躁病と比べると自殺企図率が高く，予後も悪い傾向にあることから，子どもの双極性障害傾向に関連する心理学的な要因を検討することは一次予防の観点からも重要である。本研究の結果から，ADHD傾向の特徴である不注意や多動行動の徴候の多少によって，双極性障害傾向と自己制御の下位次元との関連の仕方が異なることが示され，子どもの双極性障害傾向やそれに関わる問題行動の低減のためには，とくに興味・関心の一貫性を促すような働きかけが部分的に有効かもしれない可能性が示唆された。

Research Products

• [Journal Article] Relapse of psychiatric symptoms after discontinuation of antipsychotics in pregnant women with schizophrenia: a retrospective study. (2020)
  • Author(s): Seki, R., Hashimoto, T., Tanaka, M., Sato, A., Kimura, H., Kimura, A., Handa, S., Kanahara, N., Okayama, J., Omoto, A., Endo, M., Osone, Y., Watanabe, H., Tanaka, H., Nakazato, M., Shozu, M., & Iyo, M.
  • Journal Title: Clinical Neuropsychopharmacology and Therapeutics Volume: 11 Issue: 0 Pages: 61-66
  • DOI: 10.5234/cnpt.11.61
  • NAID: 130007921985
  • Peer Reviewed / Open Access
• [Journal Article] Inter-agency collaboration factors affecting multidisciplinary workers' ability to identify child maltreatment. (2020)
  • Author(s): Okato, A., Hashimoto, T., Tanaka, M., Saito, N., Endo, M., Okayama, J., Ichihara, A., Eshima, S., Handa, S., Senda, M., Sato, Y., Watanabe, H., Nakazato, M., & Iyo, M.
  • Journal Title: BMC research notes Volume: 13 Issue: 1 Pages: 323-323
  • DOI: 10.1186/s13104-020-05162-7
  • Peer Reviewed / Open Access
• [Journal Article] Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education (2020)
  • Author(s): Jelenkovic A, Sund R, Yokoyama Y, Latvala A, Sugawara M, et al.
  • Journal Title: Scientific Reports Volume: 10 Issue: 1 Pages: 7974-7974
  • DOI: 10.1038/s41598-020-64883-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Patterns in Psychiatrists’ Prescription of Valproate for Female Patients of Childbearing Age With Bipolar Disorder in Japan: A Questionnaire Survey (2020)
  • Author(s): Masumi Tachibana, Tasuku Hashimoto, Mami Tanaka, Hiroyuki Watanabe, Yasunori Sato, Takashi Takeuchi, Takeshi Terao, Shou Kimura, Akio Koyama, Sachie Ebisawa, Yuichiro Shizu, Terunobu Nagase, Junichi Hirakawa, Kotaro Hatta, Michiko Nakazato and Masaomi Iyo
  • Journal Title: Frontiers in Psychiatry Volume: in press Pages: 1-9
  • DOI: 10.3389/fpsyt.2020.00250
  • Peer Reviewed / Open Access
• [Journal Article] The CODATwins project: The current status and recent findings of COllaborative project of development of anthropometrical measures in twins. (2019)
  • Author(s): Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., et al.
  • Journal Title: Twin Research and Human Genetics Volume: 22(6) Pages: 800-808
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The effect of grandmothers' presence on the provision of multidisciplinary perinatal support for pregnant and postpartum women with psychosocial problems. (2019)
  • Author(s): Ogawa, M., Hashimoto, T., Tanaka, M., Tachibana, M., Seki, R., Sato, A., Okayama, J., Endo, M., Saito, N., Sato, Y., Watanabe, H., Nakazato, M., Mori, E., Shozu, M., & Iyo, M.
  • Journal Title: Journal of Multidisciplinary Healthcare Volume: 12 Pages: 1033-1041
  • DOI: 10.2147/jmdh.s228320
  • Peer Reviewed / Open Access
• [Journal Article] Parental education and genetics of BMI from infancy to old age: A pooled analysis of 29 twin cohorts. (2019)
  • Author(s): Silventoinen, K., Jelenkovic, A., Latvala, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., et al.
  • Journal Title: Obesity Volume: - Issue: 5 Pages: 855-865
  • DOI: 10.1002/oby.22451
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Impact of consuming green and yellow vegetables on the depressive symptoms of junior and senior high school students in Japan. (2019)
  • Author(s): Tanaka, M., & Hashimoto, K.
  • Journal Title: PLoS ONE Volume: 14(2) Issue: 2 Pages: e0211323-e0211323
  • DOI: 10.1371/journal.pone.0211323
  • Peer Reviewed / Open Access
• [Journal Article] 双生児法を用いた人間行動遺伝学─パーソナリティ特性と問題行動に関する心理学的知見─ (2018)
  • Author(s): 田中麻未
  • Journal Title: 罪と罰 Volume: 55(3) Pages: 44-56
• [Presentation] 母親の抑うつが子どもの自己制御と双極性障害傾向に及ぼす影響：子どものADHD傾向の有無による違い (2019)
  • Author(s): 田中麻未・高橋雄介
  • Organizer: 日本心理学会第83回大会
• [Presentation] Differences in pubertal status in genetic and environmental influences on social support and depression among Japanese adolescents. (2019)
  • Author(s): Tanaka, M., Takahashi, Y., & Sugawara, M.
  • Organizer: 49th Annual Meeting of the Behavior Genetics Association
  • Int'l Joint Research
• [Presentation] 親のソーシャル・サポートと子どもの抑うつにおける遺伝と環境 (2019)
  • Author(s): 田中麻未・高橋雄介
  • Organizer: 日本双生児研究学会第33回学術講演会
• [Presentation] 子ども期の双極性障害傾向の変化と自己制御の変化の関連性 (2018)
  • Author(s): 田中麻未・高橋雄介
  • Organizer: 日本パーソナリティ心理学会第27回大会