Development of a Musculoskeletal Finite Element Analysis Method for Supporting Orthopedic Treatment

• Project/Area Number: 18K04034
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 20010:Mechanics and mechatronics-related
• Research Institution: Chubu University
• Principal Investigator: Adachi Kazuhiko 中部大学, 工学部, 教授 (30243322)
• Project Period (FY): 2018-04-01 – 2021-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 有限要素解析 / 筋骨格モデル / 骨接合術 / インプラント / 動力学解析 / 骨折リスク評価 / 歩行解析 / 臨床バイオメカニクス

Outline of Final Research Achievements

In this study, we proposed a novel musculoskeletal finite element (MS-FE) analysis method which consists of 2 step procedure; in the 1st step, MS analysis beased on the inverse dynamic analysis for estimating the dynamic loading, and then FE analysis for obtaining the bone stress distribution in the 2nd step. Osteosynthesis with fixations is widely used for femoral neck fracture treatment. In order to reveal the potential cause of the postoperative fracture for proximal femur osteosynthesis, we applied the proposed method to the proximal femur biomechanics analysis. The dynamic loading and boundary conditions for simulating the gait motion are the major technical advantages of the proposed method comparing with the conventional static FE analysis. The simulation results successfully demonstrated the detailed time dependent stress distribution and excessive local stress concentration that is the potential cause of sub-trochanteric fractures during postoperative rehabilitation period.

Academic Significance and Societal Importance of the Research Achievements

我が国における大腿骨近位部骨折の発症者数は2007年で約15万人と報告され，高齢者人口の今後の増加に伴って患者数がさらに増加すると予想される．大腿骨近位部骨折に対する外科的治療法では整復後にインプラントで固定する骨接合術が多く用いられるが，術後リハビリテーション中あるいは日常生活復帰後に，インプラント周囲骨折や骨頭穿破など力学的要因を示唆する合併症の報告がある．本研究課題で開発したMS-FE解析方法を用いることで大腿骨近位部骨折治療の術後予測が可能となり，インプラント周囲骨折等合併症発症リスクの定量的評価につながる．

Research Products

• [Journal Article] 被験者固有の三次元有限要素モデルを用いた歩行動作下での大腿骨頚部骨接合術後の再骨折リスク評価 (2018)
  • Author(s): 中村祐貴子, 魏 綾那, 安達和彦, 野田光昭
  • Journal Title: バイオメカニズム Volume: 24 Pages: 149-157
  • NAID: 130007700359
  • Peer Reviewed
• [Presentation] 大腿骨転子部骨折術後が髄内型のカットアウト再現モデルで，骨粗鬆症の影響を検討 (2020)
  • Author(s): 野田光昭, 安達和彦
  • Organizer: 第46回日本骨折治療学会学術集会－バーチャル学術集会－
• [Presentation] MS-FE Analysis for Dynamically Postoperative Fracture Risk Assessment of Osteosynthesized Proximal Femur (2019)
  • Author(s): Kazuhiko Adachi and Mitsumasa Noda
  • Organizer: The 25th Congress of the European Society of Biomechanics
  • Int'l Joint Research
• [Presentation] 大腿骨頚部骨折後に対する歩行中の筋力を考慮した動的な有限要素解析 (2019)
  • Author(s): 野田光昭, 安達和彦
  • Organizer: 第46回日本臨床バイオメカニクス学会
  • Invited
• [Presentation] Development of a Musculoskeletal Finite Element Analysis Method for Dynamic Bone Stress Analysis of Proximal Femur (2018)
  • Author(s): K. Adachi, N. Wi, M. Noda
  • Organizer: 42nd Annual Meeting of the American Society of Biomechanics
  • Int'l Joint Research
• [Presentation] ハンソンピンおよびDSCSにより治療した大腿骨頚部骨折例に対する動的有限要素解析による応力の検討 (2018)
  • Author(s): 野田光昭, 安達和彦
  • Organizer: 第45回日本股関節学会学術集会