Advanced medical measurement technology using optical fiber

• Project/Area Number: 18K04167
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 21030:Measurement engineering-related
• Research Institution: Okayama University
• Principal Investigator: Fukano Hideki 岡山大学, 自然科学研究科, 教授 (60532992)
• Project Period (FY): 2018-04-01 – 2021-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 光ファイバ / 温度センサ / レーザ照射 / 温熱プローブ / 温熱治療 / 光ファイバ温度センサ / ハイパーサーミア / 光熱変換 / 光ファイバセンサ / 温熱療法 / 画像モニタ

Outline of Final Research Achievements

We developed a Fabry-Perot interference temperature sensor having two reflection interfaces inside a sensor probe. The sensor demonstrates excellent temperature characteristics with a linear relationship between temperature and interference wavelength. This probe operates using wavelength division multiplexing technique. Laser ablation and temperature monitoring are simultaneously performed using near-infrared semiconductor laser light and light with 1.55 μm wavelength range, respectively. The results demonstrate that the new optical fiber probe for laser ablation has high potential because it can monitor the temperature of the ablation region with fine resolution.
A graded-index multimode fiber that can provide an imaging by means of different principle with an ordinary fiber scope has been investigated using low dispersion wavelength light. It is confirmed that the light is focused with a distance that is more than 10 times longer than that of conventional technique.

Academic Significance and Societal Importance of the Research Achievements

光は，電磁信号の影響を受けないという大きなメリットを有する一方で，従来の電気信号を検出するための計測概念や計測用電子素子を用いることなく，光のみで物理量を測定する新しい手法の研究が必要である。光のみを利用する本研究の光ファイバシステムは，医療応用におけるX線CTやMRIのマクロな観察環境下で併用でき，これまでにない，治療状況判断を計測数値やミクロな細胞レベルの観察をプラスして行えるため，過剰な治療領域を無くし，患者負担の軽減と早期回復など大きな効果をもたらすことが期待できる。

Research Products

• [Journal Article] Fiber-optic temperature sensor with selectively enhanced Fabry-Perot interference using focusing effect of graded-index fiber for cryotherapy (2020)
  • Author(s): Fukano Hideki、Yoshioka Kazuki
  • Journal Title: Japanese Journal of Applied Physics Volume: 59 Issue: SO Pages: SOOD05-SOOD05
  • DOI: 10.35848/1347-4065/ab9650
  • Peer Reviewed
• [Journal Article] Fabry-Perot Optical Fiber Temperature Sensor using Graded-Index Fiber for Cryotherapy (2019)
  • Author(s): Hideki Fukano and Kazuki Yoshioka
  • Journal Title: Proceedings of 24th Microoptics Conference (MOC2019) Volume: 1 Pages: 236-237
  • DOI: 10.23919/moc46630.2019.8982783
  • Peer Reviewed
• [Presentation] ハイパーサーミアのための全ガラス製光ファイバ温度センサの提案 (2020)
  • Author(s): 三角 純平，深野 秀樹
  • Organizer: 2020年度（第71回）電気・情報関連学会中国支部連合大会
• [Presentation] 温熱療法のためのファブリ・ペロー干渉光ファイバセンサの検討 (2019)
  • Author(s): 石川 正志，深野 秀樹
  • Organizer: 令和元年度(第70回)電気・情報関連学会中国支部連合大会
• [Presentation] Fabry-Perot Optical Fiber Temperature Sensor using Graded-Index Fiber for Cryotherapy (2019)
  • Author(s): Hideki Fukano and Kazuki Yoshioka
  • Organizer: 24th Microoptics Conference (MOC2019)
  • Int'l Joint Research
• [Patent(Industrial Property Rights)] 温度変化検出装置及び温熱治療装置 (2019)
  • Inventor(s): 深野 秀樹
  • Industrial Property Rights Holder: 国立大学法人 岡山大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2019-190978
  • Filing Date: 2019