Development and applications of a non-linear discrete grey-level reconstruction method for electron tomography with a limited small number of images
| Project/Area Number |
18K04891
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 28030:Nanomaterials-related
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| Research Institution | Kogakuin University |
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Principal Investigator |
Baba Norio 工学院大学, 情報学部(情報工学部), 教授 (80164896)
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| Co-Investigator(Kenkyū-buntansha) |
馬場 美鈴 工学院大学, 総合研究所(付置研究所), 研究員 (80435528)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 電子線トモグラフィ / 電子顕微鏡 / 逆問題 / 画像再構成 / 情報欠落問題 / ナノ材料 / ナノバイオ |
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| Outline of Final Research Achievements |
Electron tomography based on the same principle as the medical X-ray CT is widely applied to various fields of biological and material science for 3D structural analysis with nano-order resolution. However, because in general the projection images of all directions are not acquired from the reason of instrumental specialty and electron physics, the depth resolution of a tomogram is considerably low. In addition, because it needs nearly 100 electron micrographs, it takes hours and there is a serious problem in practicality.
As a result of this research, we devised a new tomographic image reconstruction method to solve these problems and created the practical software. Even if the image acquisition time is shortened from 1/4 to 1/5, a clear tomographic image can be obtained without degrading the resolution along the depth direction. It is also useful for other CT such as medical X-ray CT, MRI, neutron CT, etc.
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| Academic Significance and Societal Importance of the Research Achievements |
コンピュータ断層法（ＣＴ）では、全ての方向（0°～180°）の投影データが必要ですが、この研究で取り上げた電子線（ＣＴ）のように、限られた角度範囲（ここでの例で換算して、0°～140°）しかデータが得られないＣＴもあります。このようなとき、断層像は歪みぼやけた像となります。この問題を解決しました。与えられた情報だけから欠陥を補う新たな理論を構築しました。さらに、通常１°間隔で細かく投影データを取得する必要がありますが、放射線量を減らす必要から、この間隔を8°～10°と広げても鮮明な断層像が得られます。この演算方法を広く多くのＣＴ装置に組み込めば大きく貢献できると考えています。
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Report
(4 results)
Research Products
(23 results)
