| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The composition, crystal system, crystal size and morphology of biominerals produced by biomineralization are important factors that determine their chemical and physical properties and strength. Crystallization of many biominerals proceeds in vesicles surrounded by a lipid membrane. Although it is known that there are several proteins in the vesicles that contribute to nucleation and crystal growth, crystallization in vesicles remains unexplored. In this study, we attempted to create a vesicle model using artificial liposomes and natural lipid membranes of red blood cells, and to screen crystallization conditions such as ion concentration and pH.
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