Research Project
Grant-in-Aid for Scientific Research (C)
Plants have a systemic mechanism by which local iron (Fe) starvation on one side of the root leads to a compensatory and increased Fe uptake on the other root exposed to the Fe-rich patch. However, the molecular mechanisms that control this organ-to-organ communication have not been clarified. In this study, we identified IRON MAN (IMA/FEP) as a candidate molecule that moves from leaf to root and activates Fe uptake as a mobile signaling molecule based on time-series transcriptome analysis using a split-root culture that mimics a heterogeneous soil environment. Grafting experiments also supported that IMA acts as a shoot-derived descending signal that upregulates Fe transporter genes in the roots.
大地に根を張り自ら動くことのできない植物は、脳や神経を持たない代わりに、体中に張り巡らされた維管束を利用し、根と葉のコミュニケーションによって様々な環境ストレスに柔軟に適応している。しかし、その詳細なメカニズムは明らかになっていなかった。本研究では、植物はIMA鉄結合ペプチド分子を介した器官間シグナル伝達機構により、鉄欠乏ストレスに応答して鉄吸収量を調節して個体の恒常性を維持している事を明らかにすることができた。今後は、IMAペプチドの機能改変、その利用によって、鉄などミネラル豊富な植物栽培制御への技術開発が期待される。
All 2022 2021 2020 2019 2018
All Journal Article (7 results) (of which Int'l Joint Research: 2 results, Peer Reviewed: 7 results, Open Access: 6 results) Presentation (10 results) (of which Int'l Joint Research: 1 results, Invited: 4 results) Patent(Industrial Property Rights) (1 results)
Plant Cell Physiology
Volume: - Issue: 6 Pages: 842-854
10.1093/pcp/pcac049
PLoS ONE
Volume: - Issue: 4 Pages: e0266982-e0266982
10.1371/journal.pone.0266982
Plant Physiology
Volume: 188 Issue: 4 Pages: 2364-2376
10.1093/plphys/kiac025
Science
Volume: 369 Issue: 6504 Pages: 698-702
10.1126/science.abc3710
The Plant Journal
Volume: 1 Issue: 2 Pages: 1-1
10.1111/tpj.14768
Volume: 182 Issue: 4 Pages: 2199-2212
10.1104/pp.19.00784
PLoS Genet.
Volume: 7 Issue: 3 Pages: e1007997-e1007997
10.1371/journal.pgen.1007997
120006621164
