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How does Rana virus as emerging pathogens in amphibians spread?

Research Project

Project/Area Number 18K05692
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 39060:Conservation of biological resources-related
Research InstitutionOkayama University of Science

Principal Investigator

UNE YUMI  岡山理科大学, 獣医学部, 教授 (40160303)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords新興感染症 / ラナウイルス / 両生類 / 生態系保全 / 鳥類 / 保全 / 起源 / 種の保全 / 感染症
Outline of Final Research Achievements

As a result of investigating the prevalence of ranavirus in domestic wild amphibians over time, the prevalence of toad and Indian rice frog decreased dramatically, and it was detected in Rana porosa porosa.Therefore, it was clarified that the status of RV changes in a relatively short period of time in the field. Indian rice frogs are not maintenance animals. This is because the prevalence of captive animals has decreased over time.In addition, the high rate of RV detected in carnivorous birds suggests that birds are carriers and may be deeply involved in maintaining RV in nature. It was revealed that there are species differences in susceptibility to RV. RV dynamics in nature change from moment to moment, which requires close attention to birds.

Academic Significance and Societal Importance of the Research Achievements

国内野生下両生類におけるラナウイルスの保有状況を経時的に検索した研究は、他に見当たらない。本研究によって野生下両生類において、ラナウイルスの検出率が一定しておらず、一方で検出される動物種が変わること、さらに、鳥類への感染が確認されたことから、自然界における各種動物の役割の一部が明らかにされた。これらの成果は、今後のラナウイルス対策(ラナウイルス拡散の阻止、両生類の保全など)に関して有用な情報となると考えられる。なお、本研究によって高体温の鳥類へのラナウイルス感染が初めて証明されたことは学術的意義が高い。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (8 results)

All 2020 2019 2018

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (6 results) (of which Invited: 2 results)

  • [Journal Article] Cloning of Hynobius lichenatus (Tohoku hynobiid salamander) p53 and analysis of its expression in response to radiation2020

    • Author(s)
      Kamada T, Une Y, Matsui K, Fuma S, Ikeda T, Okamoto
    • Journal Title

      BMC Genet

      Volume: 21 Issue: 1

    • DOI

      10.1186/s12863-020-00856-0

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Epidemic nodular facial myxomatous dermatitis in juvenile Cranwell’s horned frogs (Ceratophrys cranwelli).2019

    • Author(s)
      Tamukai K, Sugiyama J, Nagata Y, Tsutomu O, Katayama Y, Mizutani T, Kimura M, Une Y.
    • Journal Title

      Dis Aqua Org

      Volume: 134 Issue: 1 Pages: 57-64

    • DOI

      10.3354/dao03358

    • Related Report
      2019 Research-status Report 2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] メキシコサンショウウオ(Ambystoma mexicanum)の体腔水腫症の病理学的検索2020

    • Author(s)
      高見義紀、宇根有美
    • Organizer
      日本獣医病理学専門家協会第7回学術集会
    • Related Report
      2020 Annual Research Report 2019 Research-status Report
  • [Presentation] ボールパイソンPython regiusにおけるニドウイルス感染症の流行2019

    • Author(s)
      宇根有美、三井一鬼、逸見千寿香、藤井ひかる、赤羽良仁、田向健一
    • Organizer
      第162回日本獣医学会学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] 私たちがみているものとは2018

    • Author(s)
      宇根有美
    • Organizer
      日本爬虫両棲類学会第57回相模原大会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 若齢クランウエルツノガエルにおける顔面粘液腫症様病変の流行2018

    • Author(s)
      田向健一、杉山淳一、永田雄大、宇根有美
    • Organizer
      第17回爬虫類・両生類の臨床と病理に関するワークショップ
    • Related Report
      2018 Research-status Report
  • [Presentation] 飼育下野生動物やエキゾチックアニマルの食餌性代謝性疾患2018

    • Author(s)
      宇根有美
    • Organizer
      第1回飼育動物栄養研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] 爬虫類の感染症の病理2018

    • Author(s)
      宇根有美
    • Organizer
      エキゾチックペット研究会創立20周年記念セミナー
    • Related Report
      2018 Research-status Report
    • Invited

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Published: 2018-04-23   Modified: 2022-01-27  

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