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Physiological function of cAMP signaling in streptophytes reproducing via motile sperms

Research Project

Project/Area Number 18K06298
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 44030:Plant molecular biology and physiology-related
Research InstitutionRitsumeikan University

Principal Investigator

Kasahara Masahiro  立命館大学, 生命科学部, 教授 (70361748)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords植物cAMPシグナル伝達 / 植物cAMP / 植物cAMPシグナル伝達機構 / cAMP / cAMPシグナル系 / cAMP合成酵素 / cAMP分解酵素 / 植物精子 / CAPE
Outline of Final Research Achievements

The analysis of the Marchantia polymorpha cape-edited lines strongly suggests that CAPE is involved in sperm flagellar motility and that cAMP may act as a regulator of sperm motility. We have also isolated CAPE from ginkgo, cycad, and hornwort and clearly demonstrated that CAPE is conserved in streptophytes that reproduce via motile sperms. Furthermore, this research project has demonstrated that cAMP may have a common function as a regulator of flagellar motility throughout the living organisms.

Academic Significance and Societal Importance of the Research Achievements

ヒトにおける血糖調節などさまざまな生物で、cAMP(サイクリックAMP)が細胞内シグナル分子として重要なはたらきをもつことがわかっている。本研究において、ゼニゴケのcAMP合成・分解酵素CAPEのはたらきを調べることで、精子による有性生殖をおこなう植物の精子遊泳や精子鞭毛運動でcAMPが細胞内シグナル分子としてはたらく可能性を示唆する成果が得られた。植物研究における学術的意義のある発見である。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (10 results)

All 2021 2020 2019

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (8 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] Distribution of adenylyl cyclase/cAMP phosphodiesterase gene, CAPE, in streptophytes reproducing via motile sperm2021

    • Author(s)
      Yamamoto Chiaki、Takahashi Fumio、Ooe Yosuke、Shirahata Haruto、Shibata Aika、Kasahara Masahiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 10054-10054

    • DOI

      10.1038/s41598-021-89539-z

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characterization of the cAMP phosphodiesterase domain in plant adenylyl cyclase/cAMP phosphodiesterase CAPE from the liverwort Marchantia polymorpha2021

    • Author(s)
      Hayashida Yuta、Yamamoto Chiaki、Takahashi Fumio、Shibata Aika、Kasahara Masahiro
    • Journal Title

      Journal of Plant Research

      Volume: 135 Issue: 1 Pages: 137-144

    • DOI

      10.1007/s10265-021-01359-4

    • NAID

      40022803438

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] ゼニゴケcAMP合成・分解酵素CAPEは精子の前進遊泳に関与する2021

    • Author(s)
      山本千愛、高橋文雄、山田和正、吉川伸哉、末次憲之、河内孝之、笠原賢洋
    • Organizer
      本植物学会第85回大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 精子による生殖を行う植物はcAMP合成・分解酵素CAPEをもつ2021

    • Author(s)
      山本千愛、高橋文雄、大江遥介、白畑陽都、柴田あいか、笠原賢洋
    • Organizer
      第62回日本植物生理学会年会
    • Related Report
      2020 Research-status Report
  • [Presentation] ゼニゴケ精子の運動性におけるcAMP合成・分解酵素CAPEの機能2020

    • Author(s)
      山本千愛、高橋文雄、末次憲之、河内孝之、笠原賢洋
    • Organizer
      日本植物学会第84回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 植物cAMP合成・分解酵素遺伝子CAPEの単離と系統分布2019

    • Author(s)
      山本千愛,大江遥介,白畑陽都,柴田あいか,高橋文雄,笠原賢洋
    • Organizer
      日本植物学会第83回大会
    • Related Report
      2019 Research-status Report
  • [Presentation] ヒメツリガネゴケcAMP合成・分解酵素CAPEの機能解析2019

    • Author(s)
      堤帆乃香,高橋文雄,笠原賢洋
    • Organizer
      日本植物学会第83回大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Characterization of plant cyclic AMP function in Marchantia polymorpha2019

    • Author(s)
      Chiaki Yamamoto, Fumio Takahashi, Yousuke Ooe, Haruto Shirahata, Aika Shibata, Noriyuki Suetsugu, Takayuki Kohchi and Masahiro Kasahara
    • Organizer
      Marchantia Workshop 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 精子を作る植物に保存されたcAMP合成・分解酵素とその生理的役割2019

    • Author(s)
      笠原賢洋
    • Organizer
      2019年度(第8回)近畿植物学会講演会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] ゼニゴケの生殖時期におけるサイクリックAMPの機能解析2019

    • Author(s)
      山本千愛、高橋文雄、末次憲之、河内孝之、笠原賢洋
    • Organizer
      第60回日本植物生理学会年会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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