Epigenetic control of plant genome and gene expression by transposons
| Project/Area Number |
18K06301
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 44030:Plant molecular biology and physiology-related
|
|---|
| Research Institution | National Institute for Basic Biology |
|---|
Principal Investigator |
Atsushi Hoshino 基礎生物学研究所, 多様性生物学研究室, 助教 (80312205)
|
|---|
| Project Period (FY) |
2018-04-01 – 2022-03-31
|
| Project Status |
Completed (Fiscal Year 2021)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Keywords | エピジェネティクス / トランスポゾン / アサガオ / DNAメチル化 / ヒストン / 花 |
|---|
| Outline of Final Research Achievements |
Using the duskish mutant of Japanese morning glory as a model, transposon-induced epigenetic variation and its impact on gene expression were studied. The results outlined the relationship between DNA methylation and histone modifications of a transposon and suppression of the genes for transposition. By decoding the whole genome sequence of the duskish mutant, novel autonomous transposons were identified. Analysis of their transcripts also revealed the structure of the genes for transposition.
|
| Academic Significance and Societal Importance of the Research Achievements |
生物の多様性の獲得と進化に、エピジェネティックな変異が突然変異と同様に寄与するとされている。刷毛目絞はエピジェネティックな変異が生じて次世代に伝達するため、多様性の獲得の過程を観察していると言える。そのため本研究の成果は、エピジェネティクスの理解だけでなく、生物が多様性獲得する機構の一端に迫るものとしても意義がある。
|
Report
(5 results)
Research Products
(12 results)
