Genetic basis of adaptive traits in stream salmonids: toward a large scale population genomics
| Project/Area Number |
18K06405
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 45040:Ecology and environment-related
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| Research Institution | Hokkaido University |
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Principal Investigator |
Koizumi Itsuro 北海道大学, 地球環境科学研究院, 准教授 (50572799)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 繁殖時期 / 回遊多型 / 小進化 / 局所適応 / サケ科魚類 / メタ個体群 / 適応進化 / 遺伝的基盤 / 生態-進化動態 / 集団ゲノム学 / 河川性サケ科魚類 |
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| Outline of Final Research Achievements |
This research established an effective population genomic framework using a model system where long-term ecological data has been accumulated in 50 local populations over the last two decades. I examined large dataset and selected 78 individuals from populations above vs. below physical barriers and with early vs. late reproductive timing. Low coverage whole genome sequence suggested a few candidate genes for affecting residency vs. migratory, as well as for reproductive timing. This enables a cost-effective large scale population genomic analysis by reduced-representation sequencing.
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| Academic Significance and Societal Importance of the Research Achievements |
次世代シーケンサー（NGS）の普及により非モデル生物でもゲノム構造や適応遺伝子が調べられるようになってきた。しかし、NGS解析はいまだ高額であり、数万個体の解析はあまり現実的ではない。近年、1個体当たり多数の遺伝子座を読むのではなく、遺伝子座を絞って多数個体を解析するreduced representation sequencingという手法が考案された。本研究では、20年50個体群以上で詳細な生態データが蓄積されている調査系において、本手法を行う基盤を整えた。これにより今後数万個体規模で適応遺伝子と個体群動態を付き合わせて解析することで、野外における小進化過程を解明することが期待できる。
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Report
(4 results)
Research Products
(5 results)
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[Book] Chapter 21. Global Status of Trout and Char: Conservation Challenges in the Twenty-First Century (Book title: Trout and Char of the World)2019
Author(s)
Muhlfeld CC, Dauwalter DC, D’Angelo VS, Ferguson A, Giersch J, Impson D, Koizumi I, Kovach RP, McGinnity P, Schoeffmann J, Vollestad LA and Epifanio J
Total Pages
777
Publisher
American Fisheries Society
ISBN
9781934874547
Related Report
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