| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Episodic memory is affected by past experiences. Although prior learning enhances subsequent similar learning, the effect of prior learning on dissimilar learning remains elusive. We found that prior Y-maze learning enhanced subsequent fear-associated memory, which was dependent on the NMDA receptor activity but not on new protein synthesis. An increase in cellular ensemble that was responsible for fear memory association was observed in the amygdala of mice submitted to prior maze exploration.
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