| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We previously discovered that timing of inspiration of respiratory cycles caused the decrease of accuracy of memory tasks in humans. We then hypothesized that “when encoding is completed, then inspiration emerges”. Its contraposition must be “when inspiration does not emerge, encoding is not completed”. The following experiment must be to clarify the contraposition.
Using genetically modified mice injected with recombinant AAV, we succeeded controlling inspiratory actions of the mice using a LED light. Then, animals decreased their performance of memory retrieval when their inspiratory arrests appeared during encoding of several memory tasks. These results suggested that inspiration may play an important role in completing memory encoding.
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