| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
In this study, we developed a new thermoresponsive sol-gel transition system based on the interaction between cyclodextrin (CD) and Hydrophobically modified hydroxypropylmethyl cellulose (HM-HPMC). The potency of the HM-HPMC/CD hydrogel for use in pharmaceutical formulations was evaluated. By adding the graphene nanoparticles to the HM-HPMC/CD hydrogel, it was possible to develop a stimulus-responsive hydrogel which turns into gel in response to near-infrared light. In addition, we developed fullerene nanocomposite hydrogel where the fullerene nanoparticles was chemically linked to the hydrophilic polymer. These nanocomposite hydrogel which contains carbon nanoparticles will find numerous application in the developments of innovative medical treatments.
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