| Project/Area Number |
18K06730
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 47050:Environmental and natural pharmaceutical resources-related
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| Research Institution | Kanazawa University |
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Principal Investigator |
Sasaki Yohei 金沢大学, 薬学系, 教授 (10366833)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 国産生薬 / 栽培と加工 / 当帰 / 芍薬 / 地黄 / 川キュウ / 附子 / 生薬生産 / 修治 / 栽培効率化 / 川きゅう / 栽培 / 加工 / 資源開発 / 品質評価 / 生薬生産技術 |
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| Outline of Final Research Achievements |
The production of herbal medicine consists of both cultivation methods of original plants and processing methods of harvests technique. The purpose of this research is to "establish a processing technique for herbal medicine suitable for the Japanese environment.
Although the processing is an important process that affects the quality of herbal medicines, there are no established processing conditions in Japan, and the current situation is that private companies and farmers process them by their own methods. Therefore, I focus on five typical Chinese herbal medicines with different processing methods (Angelicae Acutilobae Radix, Peoniae Radix, Rehmanniae Radix, Cnidium Rhizoma, and Aconiti Radix Processa), I determine the optimum conditions based on scientific evidence after field investigation about China. This will be the foundation for the development of the improvement of the self-sufficiency rate of herbal medicines produced in Japan.
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| Academic Significance and Societal Importance of the Research Achievements |
日本の伝統医学である漢方は今や医師の89％が処方しており，現在の医療に欠かすことができない医療になっている。しかしその治療薬である漢方薬は，その原料の約９割を海外からの輸入品に依存している。長らく輸入品に依存しきた品目は日本には生産するための技術がない。また日本で生産技術が残っている品目も，従事者の高齢化など消失は時間の問題である。そこで筆者は日本で重要な生薬品目のうち，加工方法が異なる５品目に着目し，条件と品質の関係を明らかにする研究に着手した。安定した漢方治療の持続には生薬の安定供給は必須であり，本研究の意義は非常に大きい。
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