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Prevalence and associated factors of delayed sleep phase syndrome in Japanese

Research Project

Project/Area Number 18K07581
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52030:Psychiatry-related
Research InstitutionNeuropsychiatric Research Institute

Principal Investigator

Inoue Yuichi  公益財団法人神経研究所, 研究部, 研究員 (50213179)

Co-Investigator(Kenkyū-buntansha) 駒田 陽子  明治薬科大学, 薬学部, 准教授 (40451380)
岡島 義  東京家政大学, 人文学部, 准教授 (50509867)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords疫学調査 / 若年者 / 概日リズム / 睡眠覚醒相後退障害 / presenteeism / 社会的時差ボケ / 夜間受光 / 睡眠相後退 / 日中機能 / 抑うつ / BRIANスケール / social jet lag / 日中眠気 / 有病率 / うつ病 / social jetlag
Outline of Final Research Achievements

This study was set out to study the prevalence of delayed sleep phase disorder (DSWPD), impact of its morbidity on daytime function and associated factor of the disorder.After identifying the validity and reliability of the Japanese version of Biological Rhythms Interview of assessment (BRIAN-J)in a preliminary study, we conducted web-based questionnaire study about sleep hygiene related behaviors and the prevalence of DSWPD by using BRIAN-J targeting young generation aged 15-30 years. As a result, 4.3 % of the subject population was identified as having DSWPD, and individuals affected with DSWPD were thought to have deteriorated scores of work productivity, depression and health related quality of life. Moreover, the presence of DSWPD was thought to be associated with being student, having currently treated disease and longer liquid crystal display (LCD) viewing time.
Our result could emphasize the importance of keeping better sleep hygiene for preventing the development of DSWPD.

Academic Significance and Societal Importance of the Research Achievements

若年者でのDSWPDは決してまれでなく、日中機能に悪影響を及ぼすことが明らかになった。また、背景因子の解析から、社会的同調因子が緩い学生で発現しやすいことから、その発症予防に睡眠衛生強化が重要であることが明らかになった。これらは、医学的な治療になるとともに、睡峰以西の重要性を啓発する上で重要な資料になると考えられた。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (36 results)

All 2022 2021 2020 2019 2018

All Journal Article (28 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 24 results,  Open Access: 16 results) Presentation (6 results) Book (2 results)

  • [Journal Article] Changes in sleep behavior, sleep problems, and psychological distress/health-related quality of life of young Japanese individuals before and during the COVID-19 pandemic2022

    • Author(s)
      Tanioka Kosuke、Kayaba Momoko、Tomishima Sayaka、Komada Yoko、Inoue Yuichi
    • Journal Title

      Chronobiology International

      Volume: 39 Issue: 6 Pages: 781-791

    • DOI

      10.1080/07420528.2022.2034839

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Insomnia, anxiety, and depression during the COVID-19 pandemic: an international collaborative study2021

    • Author(s)
      Morin Charles M.、Inoue Yuchi、Han Fang、Espie Colin A.
    • Journal Title

      Sleep Medicine

      Volume: 87 Pages: 38-45

    • DOI

      10.1016/j.sleep.2021.07.035

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association of sleep duration on workdays or free days and social jetlag with job stress2021

    • Author(s)
      Takaesu Yoshikazu、Shimura Akiyoshi、Komada Yoko、Futenma Kunihiro、Ishii Miho、Sugiura Ko、Watanabe Koichiro、Inoue Yuichi
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 75 Issue: 8 Pages: 244-249

    • DOI

      10.1111/pcn.13274

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sleep Debt and Social Jetlag Associated with Sleepiness, Mood, and Work Performance among Workers in Japan2021

    • Author(s)
      Okajima Isa、Komada Yoko、Ito Wakako、Inoue Yuichi
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 18 Issue: 6 Pages: 2908-2908

    • DOI

      10.3390/ijerph18062908

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Disturbances in sleep, circadian rhythms and daytime functioning in relation to coronavirus infection and Long‐COVID ? A multinational ICOSS study2021

    • Author(s)
      Merikanto Ilona、Korman Maria、Partinen Markku、Benedict Christian、Bjelajac Adrijana、Yin Chan Ngan、Inoue Yuichi、Kirov Roumen、Landtblom Anne‐Marie、Matsui Kentaro、Morin Charles M.、Mota‐Rolim Sergio、Nadorff Michael R、Penzel Thomas、Plazzi Giuseppe
    • Journal Title

      Journal of Sleep Research

      Volume: - Issue: 4

    • DOI

      10.1111/jsr.13542

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reliability and validity of the Japanese version of the Biological Rhythms Interview of assessment in neuropsychiatry-self report for delayed sleep-wake phase disorder2021

    • Author(s)
      Kanda Yuta、Takaesu Yoshikazu、Kobayashi Mina、Komada Yoko、Futenma Kunihiro、Okajima Isa、Watanabe Koichiro、Inoue Yuichi
    • Journal Title

      Sleep Medicine

      Volume: 81 Pages: 288-293

    • DOI

      10.1016/j.sleep.2021.02.009

    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Social Jetlag Changes During the COVID-19 Pandemic as a Predictor of Insomnia ? A Multi-National Survey Study2021

    • Author(s)
      Brandao Luiz Eduardo Mateus、Morin Charles M、Espie Colin A、Bolstad Courtney、Leger Damien、Chung Frances、Plazzi Giuseppe、Dauvilliers Yves、Matsui Kentaro、De Gennaro Luigi、 Yuichi Inoue.
    • Journal Title

      Nature and Science of Sleep

      Volume: Volume 13 Pages: 1711-1722

    • DOI

      10.2147/nss.s327365

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Social jetlag among Japanese adolescents: Association with irritable mood, daytime sleepiness, fatigue, and poor academic performance2021

    • Author(s)
      Tamura Norihisa、Komada Yoko、Inoue Yuichi、Tanaka Hideki
    • Journal Title

      Chronobiology International

      Volume: 39 Issue: 3 Pages: 311-322

    • DOI

      10.1080/07420528.2021.1996388

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The bidirectional relationship between patients’ sleep disorders and their spouses’ sleep quality2021

    • Author(s)
      Inoue Yuichi
    • Journal Title

      Sleep and Biological Rhythms

      Volume: 19 Issue: 2 Pages: 111-112

    • DOI

      10.1007/s41105-021-00316-x

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prevalence and associated factors of circadian rhythm sleep-wake disorders and insomnia among visually impaired Japanese individuals2021

    • Author(s)
      Tamura Norihisa、Sasai-Sakuma Taeko、Morita Yuko、Okawa Masako、Inoue Shigeru、Inoue Yuichi
    • Journal Title

      BMC Public Health

      Volume: 21 Issue: 1 Pages: 31-31

    • DOI

      10.1186/s12889-020-09993-8

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effect of short or long sleep duration on quality of life and depression: an internet-based survey in Japan2020

    • Author(s)
      Matsui Kentaro、Kuriyama Kenichi、Yoshiike Takuya、Nagao Kentaro、Ayabe Naoko、Komada Yoko、Okajima Isa、Ito Wakako、Ishigooka Jun、Nishimura Katsuji、Inoue Yuichi
    • Journal Title

      Sleep Medicine

      Volume: 76 Pages: 80-85

    • DOI

      10.1016/j.sleep.2020.10.012

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Current state of hypnotic use disorders: Results of a survey using the Japanese version of Benzodiazepine Dependence Self‐Report Questionnaire2020

    • Author(s)
      Yamamoto Mai、Inada Ken、Enomoto Minori、Habukawa Mitsunari、Hirose Takahisa、Inoue Yuichi、Ishigooka Jun、Kamei Yuichi、Kitajima Tsuyoshi、Miyamoto Masayuki、Shinno Hideto、Nishimura Katsuji、Ozone Motohiro、Takeshima Masahiro、Suzuki Mayumi、Yamashita Hidehisa、Mishima Kazuo
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 41 Issue: 1 Pages: 14-25

    • DOI

      10.1002/npr2.12149

    • NAID

      120007042188

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Continuous tongue suction as a potential therapy for obstructive sleep apnea: A feasibility study2020

    • Author(s)
      Fukuda Tatsuya、Takei Yoichiro、Nakayama Hideaki、Inoue Yuichi、Tsuiki Satoru
    • Journal Title

      Journal of Dental Sleep Medicine

      Volume: 7 Issue: 3

    • DOI

      10.15331/jdsm.7134

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Long-term efficacy and tolerability of lemborexant compared with placebo in adults with insomnia disorder: results from the phase 3 randomized clinical trial SUNRISE 22020

    • Author(s)
      Karppa M, Yardley J, Pinner K, Filippov G, Zammit G, Moline M, Perdomo C, Inoue Y, Ishikawa K, Kubota N.
    • Journal Title

      Sleep

      Volume: 43 Issue: 9 Pages: 123-123

    • DOI

      10.1093/sleep/zsaa123

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prevalence and Associated Factors of Nocturnal Eating Behavior and Sleep-Related Eating Disorder-Like Behavior in Japanese Young Adults: Results of an Internet Survey Using Munich Parasomnia Screening2020

    • Author(s)
      Matsui Kentaro、Komada Yoko、Nishimura Katsuji、Kuriyama Kenichi、Inoue Yuichi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 4 Pages: 1243-1243

    • DOI

      10.3390/jcm9041243

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Tracking intermediate performance of vigilant attention using multiple eye metrics.2020

    • Author(s)
      Abe T, Mishima K, Kitamura S, Hida A, Inoue Y, Mizuno K, Kaida K, Nakazaki K, Motomura Y, Maruo K, Ohta T, Furukawa S, David F. Dinges, Ogata K.
    • Journal Title

      SLEEP

      Volume: 43 Issue: 3 Pages: 1-17

    • DOI

      10.1093/sleep/zsz219

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A missense variant in PER2 is associated with delayed sleep-wake phase disorder in a Japanese population.2019

    • Author(s)
      Miyagawa T, Hida A, Shimada M, Uehara C, Nishino Y, Kadotani H, Uchiyama M, Ebisawa T, Inoue Y, Kamei Y, Tokunaga K, Mishima K, Honda M.
    • Journal Title

      J Hum Genet

      Volume: 64 Issue: 12 Pages: 1219-1225

    • DOI

      10.1038/s10038-019-0665-6

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] A survey on social jetlag in Japan: a nationwide, cross-sectional Internet survey.2019

    • Author(s)
      Komada Y, Okajima I, Kitamura S, Inoue Y.
    • Journal Title

      Sleep Biol Rhythms

      Volume: 17 Issue: 4 Pages: 417-422

    • DOI

      10.1007/s41105-019-00229-w

    • NAID

      40022043168

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Correlation among clock gene expression rhythms, sleep quality, and meal conditions in delayed sleep-wake phase disorder and night eating syndrome.2019

    • Author(s)
      Haraguchi A, Komada Y, Inoue Y, Shibata S.
    • Journal Title

      Choronobiology International

      Volume: 未定 Issue: 6 Pages: 1-14

    • DOI

      10.1080/07420528.2019.1585366

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Significance of early morning insomnia for keeping the work continuity of shift workers.2019

    • Author(s)
      Inoue Y.
    • Journal Title

      Sleep Biol Rhythms

      Volume: 17 Issue: 3 Pages: 267-267

    • DOI

      10.1007/s41105-019-00227-y

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 不眠症の診断と治療2019

    • Author(s)
      井上雄一
    • Journal Title

      診断と治療社

      Volume: 107 Pages: 1113-21

    • Related Report
      2019 Research-status Report
  • [Journal Article] 睡眠薬の依存・離脱症状を考える2019

    • Author(s)
      井上雄一
    • Journal Title

      クリニシアン

      Volume: 66 Pages: 44-8

    • Related Report
      2019 Research-status Report
  • [Journal Article] Ethnic differences in periodic limb movements during sleep in patients with restless legs syndrome: a preliminary cross-sectional study of Austrian and Japanese clinical population2018

    • Author(s)
      Taeko Sasai-Sakuma, Ambra Stefani, Moeko Ochi, Birgit Hogl, Yuichi Inoue
    • Journal Title

      Sleep and Biological Rhythms

      Volume: in press Issue: 3 Pages: 345-349

    • DOI

      10.1007/s41105-018-0159-5

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Treatment of restless legs syndrome: Evidence-based review and implications for clinical practice (Revised 2017)§2018

    • Author(s)
      Winkelmann Juliane、Allen Richard P.、Hogl Birgit、Inoue Yuichi、Oertel Wolfgang、Salminen Aaro V.、Winkelman John W.、Trenkwalder Claudia、Sampaio Cristina
    • Journal Title

      Movement Disorders

      Volume: 33 Issue: 7 Pages: 1077-1091

    • DOI

      10.1002/mds.27260

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Development of a new benzodiazepine hypnotics withdrawal symptom scale2018

    • Author(s)
      Kobayashi Mina、Okajima Isa、Narisawa Hajime、Kikuchi Takashi、Matsui Kentaro、Inada Ken、Ishigooka Jun、Inoue Yuichi
    • Journal Title

      Sleep and Biological Rhythms

      Volume: 16 Issue: 3 Pages: 263-271

    • DOI

      10.1007/s41105-018-0151-0

    • NAID

      40021589188

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical significance of social jetlag in patients with excessive daytime sleepiness2018

    • Author(s)
      Kayaba Momoko、Sasai-Sakuma Taeko、Inoue Yuichi
    • Journal Title

      Chronobiology International

      Volume: 35 Issue: 12 Pages: 1637

    • DOI

      10.1080/07420528.2018.1499666

    • URL

      https://localhost/en/publications/c22c02c4-2f2a-490c-8465-1f2a7ec4cce6

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] 睡眠障害のアウトカム指標2018

    • Author(s)
      井上雄一
    • Journal Title

      精神科

      Volume: 32(5) Pages: 437-443

    • Related Report
      2018 Research-status Report
  • [Journal Article] メラトニンと睡眠2018

    • Author(s)
      栁原万里子、井上雄一
    • Journal Title

      成人病と生活習慣病

      Volume: 48(8) Pages: 853-857

    • Related Report
      2018 Research-status Report
  • [Presentation] 不眠症治療の未来を考える-出口を見据えた治療へ-2019

    • Author(s)
      井上雄一
    • Organizer
      第40回日本臨床薬理学会学術総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 睡眠障害の診断と治療Up date2019

    • Author(s)
      Inoue Y.
    • Organizer
      第49回日本神経精神薬理学会合同大会
    • Related Report
      2019 Research-status Report
  • [Presentation] うつ病の不眠を考える2019

    • Author(s)
      井上雄一
    • Organizer
      第16回日本うつ病学会総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 大学生の睡眠実態調査:睡眠不足と睡眠・覚醒リズム後退のどちらが学業と関連するか.2019

    • Author(s)
      萱場桃子, 笹井(咲間)妙子, 守田優子, 榎本みのり, 松下年子, 井上雄一
    • Organizer
      日本睡眠学会第44回定期学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] 慢性不眠症の病態に関与するクロノタイプと心理特性について2019

    • Author(s)
      岡島 義, 駒田陽子, 井上雄一
    • Organizer
      日本睡眠学会第44回定期学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] 離脱症状スケールの概要について2018

    • Author(s)
      井上雄一
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Research-status Report
  • [Book] 不眠症に対する認知行動療法マニュアル2020

    • Author(s)
      井上雄一, 岡島 義
    • Total Pages
      200
    • Publisher
      ㈱金剛出版
    • ISBN
      9784772417204
    • Related Report
      2019 Research-status Report
  • [Book] 子どもの睡眠ガイドブック -眠りの発達と睡眠障害の理解-2019

    • Author(s)
      駒田陽子,井上雄一
    • Total Pages
      184
    • Publisher
      朝倉書店
    • ISBN
      9784254301199
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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