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Early detection of adolescent depression using wearable sensors

Research Project

Project/Area Number 18K07591
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52030:Psychiatry-related
Research InstitutionHirosaki University (2020)
Kanazawa University (2018-2019)

Principal Investigator

Ono Yasuki  弘前大学, 医学研究科, 助教 (00507064)

Co-Investigator(Kenkyū-buntansha) 辻口 博聖  金沢大学, 医学系, 特任助教 (00723090)
中村 裕之  金沢大学, 医学系, 教授 (30231476)
山村 崇尚  金沢大学, 附属病院, 特任助教 (40754594)
廣澤 徹  金沢大学, 子どものこころの発達研究センター, 特任助教 (80645127)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2018: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsウエアラブルセンサー / メンタルヘルス / 思春期うつ病 / 心拍変動 / 加速度計 / インターネット依存 / 起立試験 / 起立性調節障害 / 呼吸性心拍変動 / 自律神経系 / 思春期うつ状態
Outline of Final Research Achievements

For 29 junior high school students, wearable sensors were used to measure changes in heart rate variability from electrocardiograms, and physical activity and sleep indices from accelerometers.Mean age 13.7 years, Depression DSRS 8.9 Young's internet dependence was 40.5,.Autism Index 14.9, ADHD-RS Inattention 5.6 Hyperactivity Impulsivity 2.2, STAI assessed anxiety 41.8 for trait anxiety, 37.7 for state anxiety, and 22 for smartphone dependence. Other than boys being more prone to ADHD than girls, no gender differences were found in other indicators. There was a correlation between the degree of internet dependence and the degree of HF recovery at night, and the higher the degree of internet dependence, the greater the change in autonomic nervous system at night. The higher the level of internet dependence, the greater the nocturnal autonomic changes. The change in heart rate in the orthostatic test was correlated with the nocturnal HF recovery.

Academic Significance and Societal Importance of the Research Achievements

ウエアラブルセンサーは近年注目を集めているが、その有用性につき中学生について検討した。抑うつに関しては、早期発見への有用性は得られなかったが、加速度計で得られた情報からは、ネット依存が睡眠に及ぼす悪影響を確認することができた。また中学生は起立性調節障害が生じる時期であるが、24時間の心拍変動の差が起立試験の結果とほぼ相関しており、自律神経系の評価に有用であることが明らかになった。今後は起立性調節性障害の病態解明のため、健常者との比較が期待される。また加速度計は装着の負担が少ないので、睡眠衛生の指導にも有用であると考えられた。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (8 results)

All 2021 2020 2019

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (5 results)

  • [Journal Article] Influence of oxytocin administration on somatosensory evoked magnetic fields induced by median nerve stimulation during hand action observation in healthy male volunteers2021

    • Author(s)
      Ono Y, Hirosawa T, Hasegawa C, Ikeda T, Kudo K, Naito N, Yoshimura Y, Kikuchi M.
    • Journal Title

      PlosOne

      Volume: 16 Issue: 3 Pages: 1-13

    • DOI

      10.1371/journal.pone.0249167

    • Related Report
      2020 Annual Research Report
    • Open Access
  • [Journal Article] Auditory steady-state response at 20Hz and 40Hz in young typically developing children and children with autism spectrum disorder2020

    • Author(s)
      Ono Y, Kudoh K, Ikeda T, Takahashi T, Yoshimura Y, Minabe Y, Kikuchi M
    • Journal Title

      Psychiatry Clin Neurosci.

      Volume: 10 Issue: 6 Pages: 1-9

    • DOI

      10.1111/pcn.12998

    • Related Report
      2020 Annual Research Report 2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationship between Autistic Traits and Nutrient Intake among Japanese Children and Adolescents2020

    • Author(s)
      Tsujiguchi Hiromasa、Miyagi Sakae、Nguyen Thao Thi Thu、Hara Akinori、Ono Yasuki、Kambayashi Yasuhiro、Shimizu Yukari、Nakamura Haruki、Suzuki Keita、Suzuki Fumihiko、Nakamura Hiroyuki
    • Journal Title

      Nutrients

      Volume: 12 Issue: 8 Pages: 2258-2258

    • DOI

      10.3390/nu12082258

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 起立性調節障害におけるウエアラブルセンサーの有用性について;24時間心拍変動と加速度計2020

    • Author(s)
      小野靖樹、中村和彦、菊知充
    • Organizer
      日本児童青年精神医学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ウエアラブルセンサーを用いたメンタルストレスの早期発見2019

    • Author(s)
      小野靖樹, 辻口博聖, 中村裕之, 菊知充
    • Organizer
      日本児童青年精神医学会
    • Related Report
      2019 Research-status Report
  • [Presentation] Cognitive reseve in bipolar disorder2019

    • Author(s)
      小野靖樹、佐藤邦子、松井三枝、菊知充
    • Organizer
      Kanazawa University International Symposium
    • Related Report
      2019 Research-status Report
  • [Presentation] 精神疾患における前頭葉機能の低下の関連要因2019

    • Author(s)
      小野靖樹、佐藤邦子、松井三枝、菊知充
    • Organizer
      日本光脳機能イメージング学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 幼児期の定型発達と自閉症における定常聴性反応の違い2019

    • Author(s)
      小野靖樹、工藤究、池田尊司、吉村優子、三邉義雄、菊知充
    • Organizer
      第35回日本脳電磁図
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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