Development of preemptive medicine for late complications of pediatric and AYA cancer patients
| Project/Area Number |
18K07842
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 52050:Embryonic medicine and pediatrics-related
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| Research Institution | Osaka Shoin Women's University (2020-2022)
Osaka University (2018-2019) |
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Principal Investigator |
MIYOSHI Yoko 大阪樟蔭女子大学, 健康栄養学部, 教授 (40457023)
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| Project Period (FY) |
2018-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 小児がん / 晩期合併症 / AYA世代がん / 移行期医療 / 内分泌異常 / 妊孕性温存 / AYA世代 / 長期フォローアップ / 移行期（トランジション） / がん・生殖医療 / 妊孕性 / 小児がん経験者 / AYA |
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| Outline of Final Research Achievements |
Children and adolescent and young adult (AYA) cancer patients are at risk of late complications and have a high frequency of endocrine abnormalities. Many childhood cancer survivors (CCS) do not receive appropriate medical care due to a gradual lack of follow-up during the transition to adult care. Therefore, in this project, we conducted a questionnaire about transitional medical care in the endocrine area of pediatric cancer patients, and clarified the current situation and problems in Japan. We also worked on the dissemination of fertility preservation for cancer patients.
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| Academic Significance and Societal Importance of the Research Achievements |
小児・AYA世代がん患者における晩期合併症の発症予防を目的に、本研究課題を遂行した。とりわけ頻度の高い内分泌異常への対策が喫緊の課題であることから、小児・AYA世代がん患者の長期フォローアップにおいて内分泌領域における包括的な診療体制構築と、適切な移行期医療の提供、妊孕性温存療法の普及に向けた支援に取り組んだ。患者の紹介側である小児科と受入側である成人診療科において、それぞれ移行期医療の現状と問題点を抽出することにより、医療現場に置いて今後取り組むべき課題が明らかとなった。
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Report
(6 results)
Research Products
(45 results)
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[Journal Article] Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for fertility preservation in childhood, adolescent, and young adult cancer patients: part 2.2022
Author(s)
Tozawa A, Kimura F, Takai Y, Nakajima T, Ushijima K, Kobayashi H, Satoh T, Harada M, Sugimoto K, Saji S, Shimizu C, Akiyama K, Bando H, Kuwahara A, Furui T, Okada H, Kawai K, Shinohara N, Nagao K, Kitajima M, Suenobu S, Soejima T, Miyachi M, Miyoshi Y, et l.
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Journal Title
Int J Clin Oncol
Volume: 27(2)
Issue: 2
Pages: 281-300
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] A nationwide questionnaire survey targeting Japanese pediatric endocrinologists regarding transitional care in childhood, adolescent, and young adult cancer survivors2020
Author(s)
Miyoshi Y, Yorifuji T, Shimizu C, Nagasaki K, Kawai M, Ishiguro H, Okada S, Kanno J, Takubo N, Muroya K, Ito J, Horikawa R, Yokoya S, Ozono K.
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Journal Title
Clinical Pediatric Endocrinology
Volume: 29
Issue: 2
Pages: 55-62
DOI
NAID
ISSN
0918-5739, 1347-7358
Related Report
Peer Reviewed / Open Access
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[Presentation] 小児・AYA世代がん患者の内分泌診療における移行期医療の現状（日本小児内分泌学会全国調査）2020
Author(s)
三善陽子, 依藤亨, 横谷進, 長崎啓祐, 川井正信, 石黒寛之, 岡田賢, 菅野潤子, 田久保憲行, 室谷浩二, 伊藤純子, 堀川玲子, 清水千佳子, 大薗恵一
Organizer
第10回日本がん・生殖医療学会
Related Report
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[Presentation] シンポジウム7. 小児がんの内分泌診療：現場のニーズとガイドライン.新：小児がん内分泌診療の手引きについて2019
Author(s)
依藤亨, 三善陽子, 石黒寛之, 伊藤純子, 岡田賢, 川井正信, 菅野潤子, 堀川玲子, 田久保憲行, 長崎啓祐, 室谷浩二
Organizer
第53回小児内分泌学会学術集会
Related Report
Invited
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[Presentation] nation-wide questionnaire survey targeting Japanese pediatric endocrinologists regarding transitional care in pediatric and adolescent and young adult (AYA) cancer survivors2019
Author(s)
Miyoshi Y, Yorifuji T, Yokoya S, Nagasaki K, Kawai M, Ishiguro H, Okada S, Kanno J, Takubo N, Muroya K, Ito J, Horikawa R, Shimizu C, Ozono K
Organizer
The 58th Annual European Society for Paediatric Endocrinology (ESPE) Meeting
Related Report
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[Presentation] 小児・AYA世代がん患者の内分泌診療における移行期に関する全国調査結果2019
Author(s)
三善陽子, 依藤亨, 横谷進, 長崎啓祐, 川井正信, 石黒寛之, 岡田賢, 菅野潤子, 田久保憲行, 室谷浩二, 伊藤純子, 堀川玲子, 清水千佳子, 大薗恵一
Organizer
第53回日本小児内分泌学会学術集会
Related Report
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[Presentation] A multi-center questionnaire survey regarding acceptance of long-term follow-up in AYA cancer patients2019
Author(s)
Miyoshi Y, Higuchi A, Suzuki T, Isoyama K, Kawai Y, Tatara R, Tokunaga E, Ishida Y, Iguchi M, Suzuki N, Kiyotani C, Ozawa M, Yamamoto K, Ishida Y, Horibe K, Shimizu C
Organizer
第61回日本小児血液・がん学会学術集会
Related Report
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