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Development of the new PEEK cervical spine spacer with high safety and excellent bone conduction

Research Project

Project/Area Number 18K08941
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 56010:Neurosurgery-related
Research InstitutionShinshu University

Principal Investigator

Ito Kiyoshi  信州大学, 学術研究院医学系(医学部附属病院), 准教授 (00362111)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsインプラント / 脊椎脊髄疾患 / ハイドロキシアパタイト / ポリエーテルエーテルケトン / 頚椎インプラント / 骨形成性 / 脊椎脊髄外科 / PEEK
Outline of Final Research Achievements

Regarding this subject, we refrain from providing detailed information in the patent application, but first we were able to do it on a plane where thermal spraying can be performed relatively uniformly. Although the thermal spraying conditions cannot be clarified, it was found that hydroxyapatite can be sprayed by the AD method. However, on the other hand, it is not possible at present to spray hydroxyapatite other than plate-shaped PEEK, and there remains a problem of how to perform uniform spraying on columnar PEEK. Some of the actual implants are rectangular parallelepipeds made by layering plate-like ones, which is a reference point when making implants by spraying hydroxyapatite on PEEK.

Academic Significance and Societal Importance of the Research Achievements

プラスティック基材に対して、ブラスト処理などをおこなうことなく、骨形成性物質であるハイドロキシアパタイトを溶射することが可能であるということを実証できた。従来プラスティック基材の表面は比較的滑らかであり、そこに溶射するということは不可能に近いと考えられていた。産業総合研究所によるAD法の学術的および社会的貢献は大きいと考えられる。

Report

(2 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Research-status Report
  • Research Products

    (10 results)

All 2020

All Journal Article (5 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (5 results) (of which Invited: 3 results)

  • [Journal Article] 最新の知見2 ロボティックスの脊椎手術への応用2020

    • Author(s)
      伊東清志
    • Journal Title

      最新主要文献でみる脳神経外科学レビュー

      Volume: 4 Pages: 173-181

    • Related Report
      2020 Research-status Report
  • [Journal Article] Microanatomy of the dura mater at the craniovertebral junction and spinal region for safe and effective surgical treatment.2020

    • Author(s)
      Ito K, Yamada M, Horiuchi T, Hongo K.
    • Journal Title

      J Neurosurg Spine

      Volume: 33 Issue: 2 Pages: 165-171

    • DOI

      10.3171/2020.1.spine191424

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Appropriate surgical procedures for Chiari type 1 malformation and associated syrinx based on radiological characteristics of the craniovertebral junction.2020

    • Author(s)
      Ito K, Yamada M, Horiuchi T, Hongo K
    • Journal Title

      Neurosurg Rev

      Volume: 43 Issue: 2 Pages: 575-580

    • DOI

      10.1007/s10143-019-01079-3

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] 脊髄・脊椎疾患】脊髄腫瘍 診断のピットフォールと手術戦略.2020

    • Author(s)
      伊東清志, 中村卓也, 宮岡嘉就, 窪田 樹, 堀内哲吉, 本郷一博
    • Journal Title

      脳神経外科ジャーナル

      Volume: 28 Pages: 278-285

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 解剖を中心とした脳神経手術手技 ロボティックスの脊椎脊髄治療への応用2020

    • Author(s)
      伊東清志, 中村卓也, 堀内哲吉
    • Journal Title

      脳神経外科

      Volume: 48 Pages: 385-395

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Presentation] The First Case of Total Disc Replacement For Cervical Radiculopathy Using an Artificial Mobi-C Disc2020

    • Author(s)
      伊東清志
    • Organizer
      第61回中部脊髄外科ワークショップ
    • Related Report
      2020 Research-status Report
  • [Presentation] Long-term Surgical Results and Surgical Strategy of the Spinal Neurinoma via Posterior Approach2020

    • Author(s)
      伊東清志
    • Organizer
      第38回日本脳神経外科コングレス総会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] Pitfalls of the Preoperative Diagnosis and Surgical Strategy for Spinal Cord Tumors2020

    • Author(s)
      伊東清志
    • Organizer
      第38回日本脳神経外科コングレス総会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 多孔質発泡チタンの骨形成における組織学的・力学的・放射線学的検討2020

    • Author(s)
      伊東清志
    • Organizer
      第47回日本脊椎脊髄病学会学術集会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] Surgical Treatment of Cervical Spondylosis in Patients Equal or Over 80 Years Old2020

    • Author(s)
      伊東清志
    • Organizer
      第31回日本老年脳神経外科学会
    • Related Report
      2020 Research-status Report

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Published: 2018-04-23   Modified: 2025-03-27  

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