| Project/Area Number |
18K09102
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 56020:Orthopedics-related
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| Research Institution | Nagoya University |
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Principal Investigator |
Imagama Shiro 名古屋大学, 医学系研究科, 教授 (40467288)
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| Co-Investigator(Kenkyū-buntansha) |
小林 和克 名古屋大学, 医学部附属病院, 病院講師 (00706294)
安藤 圭 名古屋大学, 医学部附属病院, 講師 (40566973)
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| Project Period (FY) |
2018-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 高齢者 / 運動器疾患 / 介入プログラム / 健康寿命延伸 / 運動器慢性疾患 / 骨粗鬆症 / 変形性膝関節症 / 変形性腰椎症 / 高齢者運動器疾患 |
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| Outline of Final Research Achievements |
We tried to identify the factors related to the absence of musculoskeletal degenerative disease (MSD) in multivariate logistic regression analysis in 1034 volunteers (444 men, 590 women, mean age 63.5 years) in the Yakumo study. In multivariate logistic regression analysis adjusted for age and sex, lower body mass index (odds ratio [OR] 1.10, P < 0.001), lower spinal inclination (OR 1.08, P < 0.01), higher back muscle strength (OR 1.01, P < 0.05), no locomotive syndrome (OR 1.80, P < 0.05) and good body balance (OR: 1.12, P < 0.05)
were significant factors for the absence of MSD. According to this research, we can establish a health intervention program for healthy middle-aged and older people.
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| Academic Significance and Societal Importance of the Research Achievements |
高齢者疫学研究データを用いて多変量解析を行った結果、BMI低値、歩行速度維持、重心動揺安定、背筋力維持、脊柱前傾角少、ロコモなしが運動器慢性疾患（骨粗鬆症、変形性膝関節症、変形性腰椎症）が一つもない有意な関連因子であることが初めて判明した。本研究により運動器慢性疾患を予防しうる関連因子が同定でき、これらに介入する運動・栄養プログラムを策定し高齢者の健康寿命延伸に貢献できる。
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