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Development and Multiaxial Evaluation of a Temperature-Controlled moisturizing Method.

Research Project

Project/Area Number 18K09665
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionKagoshima University

Principal Investigator

Murakami Mamoru  鹿児島大学, 医歯学域鹿児島大学病院, 講師 (80264448)

Co-Investigator(Kenkyū-buntansha) 西村 正宏  鹿児島大学, 医歯学域歯学系, 教授 (00294570)
西 恭宏  鹿児島大学, 医歯学域歯学系, 准教授 (10189251)
藤島 慶  鹿児島大学, 医歯学域歯学系, 助教 (50553153)
原田 佳枝  鹿児島大学, 医歯学域歯学系, 助教 (60432663)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords口腔乾燥症 / 口腔保湿剤
Outline of Final Research Achievements

The purpose of this study was to evaluate the effectiveness of a temperature-controlled moisturizing method. The results of sensory test showed that the significant difference between men and women in the VAS score was reduced when the moisturizer was heated to 37°C. Examination of the heating and cooling conditions of the moisturizers showed that the antifungal activity of the moisturizers was related to the type of moisturizer and storage temperature, with the highest antifungal activity when the moisturizers were stored at 37°C.

Academic Significance and Societal Importance of the Research Achievements

口腔乾燥症患者は,推定3000万人以上とも言われており,対症療法として保湿剤が用いられているが,その適用基準は十分には確立されていない.
口腔乾燥症患者は女性が多く,また,口腔カンジダ症を併発することが多いが,保湿剤の加温により嗜好性に関する性差が減少した結果や抗真菌性が増加した結果は,既存の保湿剤を利用した新規保湿法としての有効性を示し,口腔乾燥症に対する治療効果の向上や超高齢社会において今後ますます増加すると考えられる口腔乾燥症患者のQOL向上に寄与できると考えられる.

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (9 results)

All 2021 2020 2019 2018 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (5 results) (of which Int'l Joint Research: 1 results) Remarks (2 results)

  • [Journal Article] Effects of Storage Temperature and pH on the Antifungal Effects of Commercial Oral Moisturizers against Candida Albicans and Candida Glabrata2020

    • Author(s)
      Murakami M, Harada K, Nishi Y, Shimizu T, Motoyama S, Nishimura M.
    • Journal Title

      Medicina

      Volume: 56 Issue: 10 Pages: 252-252

    • DOI

      10.3390/medicina56100525

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Storage Temperatures and Type of Oral Moisturizers on their Antifungal Effects2018

    • Author(s)
      Murakami M, Fujishima K, Nishi Y, Harada K,Nishimura M.
    • Journal Title

      Oral Health and Dental Management

      Volume: 17-6 Pages: 1057-1062

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Storage temperature and pH of commercial oral moisturizers affects the antifungal effects2021

    • Author(s)
      M. Murakami, K. Harada, Y. Nishi and M. Nishimura
    • Organizer
      7th Biennial Joint Congress of JPS-CPS-KAP
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 口腔保湿剤の保管温度ならびにpHが抗真菌性に及ぼす影響2021

    • Author(s)
      村上 格,原田佳枝,元山彩良,西 恭宏,西村正宏
    • Organizer
      日本老年歯科医学会第31回学術大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 医療従事者における口腔保湿剤の認知度ならびに指導実態の調査.2019

    • Author(s)
      村上 格,西 恭宏,原田佳枝,西村正宏.
    • Organizer
      第30回日本老年歯科医学会学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 口腔保湿剤の保管温度と種類がその抗真菌性に及ぼす影響2018

    • Author(s)
      村上 格,藤島 慶,原田佳枝,西 恭宏,西村正宏
    • Organizer
      日本補綴歯科学会 第127回学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 口腔保湿剤の認知度ならびに指導実態に関するアンケート調査2018

    • Author(s)
      元山彩良,村上 格,西 恭宏,西村正宏
    • Organizer
      平成30年度 日本補綴歯科学会 九州支部学術大会
    • Related Report
      2018 Research-status Report
  • [Remarks] 顎顔面欠損補綴と口腔乾燥への対応

    • URL

      http://w3.hal.kagoshima-u.ac.jp/dental/prostho2/20200203%E3%80%80Gakuganmenhotetsu%20to%20koukuukannsou.pdf

    • Related Report
      2020 Annual Research Report 2019 Research-status Report
  • [Remarks] 顎顔面欠損補綴と口腔乾燥への対応

    • URL

      http://w3.hal.kagoshima-u.ac.jp/dental/prostho2/20180507gakuhotetsu1.pdf

    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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