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To approach the issue of the discrepancy between form and function in the eldery in terms of sarcopenia of the masticatory muscles.

Research Project

Project/Area Number 18K09674
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionTohoku University

Principal Investigator

Ohi Takashi  東北大学, 歯学研究科, 非常勤講師 (10396450)

Co-Investigator(Kenkyū-buntansha) 遠藤 耕生  東北大学, 歯学研究科, 大学院非常勤講師 (30756292)
服部 佳功  東北大学, 歯学研究科, 教授 (40238035)
Project Period (FY) 2018-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2021: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords口腔機能 / 咀嚼筋 / サルコぺニア / 高齢者 / 口腔保健 / コホート研究 / サルコペニア / 咀嚼機能
Outline of Final Research Achievements

To test the hypothesis that the existence of sarcopenia of masticatory muscles may be behind the "discrepancy between form and function" in elderly people who cannot fully exercise masticatory function despite having 20 or more teeth, 253 general local residents aged 55 or older were surveyed.
The results showed that among 138 people who had more than 20 teeth, 5 had decreased masticatory function, and 3 of them had "discrepancy between form and function" with sarcopenia of masticatory muscles. One of the reasons for the low frequency of "discrepancy between form and function" was that the subjects were relatively young. Another reason may be that the sample size was not large enough. In the future, it will be necessary to further expand the cohort and pursue the "discrepancy between form and function" in the elderly.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果、20歯以上を有しているにも関わらず十分な咀嚼機能を発揮できない『形態と機能の乖離』のある者は、比較的若い高齢者には少ないことが明らかになった。今後更にコホートを拡大し、高齢者の咀嚼筋サルコペニアと『形態と機能の乖離』との関連が明らかとなれば、歯科治療の需要が形態回復に主眼を置いた「健常者型」から機能回復に主眼を置いた「高齢者型」にシフトすると予測される本邦の現状に即した口腔保健への提言が可能となると考えられる。

Report

(7 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (27 results)

All 2023 2022 2021 2020 2019 2018

All Journal Article (14 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 14 results,  Open Access: 7 results) Presentation (13 results)

  • [Journal Article] Associations of Dental Health With the Progression of Hippocampal Atrophy in Community-Dwelling Individuals2023

    • Author(s)
      Yamaguchi Satoshi,Murakami Takahisa,Satoh Michihiro,Komiyama Takamasa,Ohi Takashi,Miyoshi Yoshitada,Endo Kosei,Hiratsuka Takako,Hara Azusa,Tatsumi Yukako,Totsune Tomoko,Asayama Kei,Kikuya Masahiro,Nomura Kyoko,Hozawa Atsushi,Metoki Hirohito,Imai Yutaka,Watanabe Makoto,Ohkubo Takayoshi,Hattori Yoshinori
    • Journal Title

      Neurology

      Volume: 101 Issue: 10

    • DOI

      10.1212/wnl.0000000000207579

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Oral health-related quality of life is associated with the prevalence and development of depressive symptoms in older Japanese individuals: The Ohasama Study2022

    • Author(s)
      Ohi Takashi、Murakami Takahisa、Komiyama Takamasa、Miyoshi Yoshitada、Endo Kosei、Hiratsuka Takako、Satoh Michihiro、Asayama Kei、Inoue Ryusuke、Kikuya Masahiro、Metoki Hirohito、Hozawa Atsushi、Imai Yutaka、Watanabe Makoto、Ohkubo Takayoshi、Hattori Yoshinori
    • Journal Title

      Gerodontology

      Volume: 39 Issue: 2 Pages: 204

    • DOI

      10.1111/ger.12557

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study2022

    • Author(s)
      Sho Yamada,Takamasa Komiyama,Takashi Ohi,Takahisa Murakami,Yoshitada Miyoshi,Kosei Endo,Takako Hiratsuka,Azusa Hara,Michihiro Satoh,Yukako Tatsumi,Ryusuke Inoue,Kei Asayama,Masahiro Kikuya,Atsushi Hozawa,Hirohito Metoki,Yutaka Imai,Takayoshi Ohkubo,Yoshinori Hattori
    • Journal Title

      J Periodontal Res.

      Volume: 57 Issue: 3 Pages: 615

    • DOI

      10.1111/jre.12990

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between maximum occlusal force and gastrointestinal cancer in community-dwelling older Japanese adults2022

    • Author(s)
      Komiyama Takamasa、Ohi Takashi、Ito Wakana、Miyoshi Yoshitada、Hiratsuka Takako、Matsuyama Sanae、Tsuji Ichiro、Watanabe Makoto、Hattori Yoshinori
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 440-440

    • DOI

      10.1038/s41598-021-04158-y

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship Between Oral Health and Fractures in Community-Dwelling Older Japanese Adults2021

    • Author(s)
      Ito Wakana、Komiyama Takamasa、Ohi Takashi、Hiratsuka Takako、Matsuyama Sanae、Sone Toshimasa、Tsuji Ichiro、Watanabe Makoto、Hattori Yoshinori
    • Journal Title

      Journal of the American Medical Directors Association

      Volume: in press Issue: 6 Pages: 1184-1189.e1

    • DOI

      10.1016/j.jamda.2021.01.058

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dental Status is Associated With Incident Functional Disability in Community-Dwelling Older Japanese: A Prospective Cohort Study Using Propensity Score Matching2020

    • Author(s)
      Takamasa Komiyama, Takashi Ohi, Yasutake Tomata, Fumiya Tanji, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori
    • Journal Title

      Journal of Epidemiology

      Volume: 30 Issue: 2 Pages: 84-90

    • DOI

      10.2188/jea.JE20180203

    • NAID

      130007795073

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2020-02-05
    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 25.Cognitive impairment and depressive symptoms lead to biases in self-evaluated masticatory performance among community-dwelling older Japanese adults: the Tsurugaya Project2020

    • Author(s)
      Takamasa Komiyama, Takashi Ohi, Takako Hiratsuka, Yoshitada Miyoshi, Yasutake Tomata, Shu Zhang, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori.
    • Journal Title

      Journal of Dentistry

      Volume: 99 Pages: 103403-103403

    • DOI

      10.1016/j.jdent.2020.103403

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] 26.Verification of the criteria for reduced occlusal force to diagnose oral hypofunction in older Japanese people: A prospective cohort study on incident functional disability2020

    • Author(s)
      Takamasa Komiyama, Takashi Ohi, Yoshitada Miyoshi, Yasutake Tomata, Shu Zhang, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori.
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 8 Pages: 989-997

    • DOI

      10.1111/joor.13021

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] The Association between Number of Remaining Teeth and Maintenance of Successful Aging in Japanese Older People: A 9-Year Longitudinal Study2020

    • Author(s)
      Fumiya Tanji, Takamasa Komiyama, Takashi Ohi, Yoshinori Hattori, Makoto Watanabe, Yukai Lu, Ichiro Tsuji.
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 252 Issue: 3 Pages: 245-252

    • DOI

      10.1620/tjem.252.245

    • NAID

      130007937235

    • ISSN
      0040-8727, 1349-3329
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The association between bilateral maximum occlusal force and all-cause mortality among community-dwelling older adults: The Tsurugaya project2020

    • Author(s)
      Ohi Takashi、Komiyama Takamasa、Miyoshi Yoshitada、Murakami Takahisa、Tsuboi Akito、Tomata Yasutake、Tsuji Ichiro、Watanabe Makoto、Hattori Yoshinori
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 64 Issue: 3 Pages: 289-295

    • DOI

      10.1016/j.jpor.2019.08.005

    • NAID

      130007885755

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Contribution of Systemic Inflammation and Nutritional Status to the Relationship Between Tooth Loss and Mortality in a Community-Dwelling Older Japanese Population: A Mediation Analysis of Data From the Tsurugaya Project2019

    • Author(s)
      Takako Hiratsuka, Takamasa Komiyama, Takashi Ohi, Fumiya Tanji, Yasutake Tomata, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori
    • Journal Title

      Clinical oral investigations

      Volume: - Issue: 6 Pages: 2071-2077

    • DOI

      10.1007/s00784-019-03072-y

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Maximum Occlusal Force and Incident Functional Disability in Older Adults: The Tsurugaya Project2018

    • Author(s)
      Ohi T.、Komiyama T.、Miyoshi Y.、Murakami T.、Tsuboi A.、Tomata Y.、Tsuji I.、Watanabe M.、Hattori Y.
    • Journal Title

      JDR Clinical & Translational Research

      Volume: 3 Issue: 2 Pages: 195-202

    • DOI

      10.1177/2380084418761329

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between status of dentition and incident functional disability in an elderly Japanese population: prospective cohort study of the Tsurugaya project2018

    • Author(s)
      Komiyama Takamasa、Ohi Takashi、Miyoshi Yoshitada、Murakami Takahisa、Tsuboi Akito、Tomata Yasutake、Tsuji Ichiro、Watanabe Makoto、Hattori Yoshinori
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 62 Issue: 4 Pages: 443-448

    • DOI

      10.1016/j.jpor.2018.04.003

    • NAID

      130007521608

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: A 4-year prospective cohort study from the Ohasama study2018

    • Author(s)
      Saito Sho、Ohi Takashi、Murakami Takahisa、Komiyama Takamasa、Miyoshi Yoshitada、Endo Kosei、Satoh Michihiro、Asayama Kei、Inoue Ryusuke、Kikuya Masahiro、Metoki Hirohito、Imai Yutaka、Ohkubo Takayoshi、Hattori Yoshinori
    • Journal Title

      BMC Oral Health

      Volume: 18 Issue: 1 Pages: 1-8

    • DOI

      10.1186/s12903-018-0602-7

    • URL

      https://pure.teikyo.jp/en/publications/65661375-aa77-4969-9d91-0af4d714c239

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 20歯未満の地域高齢者の死亡発生に対する口腔の形態と機能回復の効果:17年間の前向きコホート研究2023

    • Author(s)
      関大蔵,小宮山貴将,大井孝,三好慶忠 ,渡邉 誠,服部佳功.
    • Organizer
      日本補綴歯科学会 第132回学術大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 現在歯数と歯周炎の交互作用が脳形態変化に与える影響 大迫研究における縦断 MRI 解析2022

    • Author(s)
      山口哲史, 小宮山貴将, 大井 孝, 村上任尚, 佐藤倫広, 沼崎貴子, 三好慶忠, 遠藤耕生, 山田 唱, 目時弘仁, 大久保孝義, 服部佳功.
    • Organizer
      日本補綴歯科学会 第131回学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 地域高齢者における最大咬合力と消化器がんとの関連:鶴ケ谷プロジェクト2022

    • Author(s)
      小宮山貴将, 大井 孝, 伊藤和花菜, 三好慶忠, 平塚貴子, 松山紗奈江, 辻 一郎, 渡邉 誠, 服部佳功
    • Organizer
      第32回日本疫学会学術総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 地域一般住民における歯科定期受診とアテローム性動脈硬化との関連 ー大迫研究-2021

    • Author(s)
      山田 唱, 小宮山貴将, 大井 孝, 村上任尚, 平塚貴子, 三好慶忠, 遠藤耕生, 大久保孝義, 服部佳功
    • Organizer
      日本老年歯科医学会第32回学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 地域高齢者における口腔保健指標と転倒による骨折発生との関連2021

    • Author(s)
      伊藤和花菜,小宮山貴将,大井 孝,平塚貴子,渡邉 誠,服部佳功
    • Organizer
      日本補綴歯科学会第130回学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 地域高齢者における現在歯数および最大咬合力と要介護認定との関連2020

    • Author(s)
      伊藤和花菜,小宮山貴将,大井 孝,平塚貴子,山田 唱,服部佳功.
    • Organizer
      日本老年歯科医学会第31回学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 地域高齢者の低栄養が咬合力低下と死亡発生の関連を媒介する効果:鶴ケ谷プロジェクト2019

    • Author(s)
      平塚貴子,小宮山貴将,大井 孝,渡邉 誠,服部佳功
    • Organizer
      日本補綴歯科学会第128回学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 20歯未満の地域高齢者における介護予防と関連する口腔保健指標の検討2019

    • Author(s)
      小宮山 貴将,大井 孝,三好 慶忠,平塚 貴子,渡邉 誠 ,服部 佳功
    • Organizer
      日本老年歯科医学会第30回学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Deviation of Subjective and Objective Masticatory Ability in Older Adults2019

    • Author(s)
      T Komiyama, T Ohi, Y. Miyoshi, T Hiratsuka, Y Tomata, S Zhang, I Tsuji, M Watanabe, Y Hattori.
    • Organizer
      96th General Session & Exhibition of the IADR
    • Related Report
      2019 Research-status Report
  • [Presentation] 地域在住有歯顎高齢者の低咬合力と要介護発生リスク ―残存歯数の層別化に基づく検討―2019

    • Author(s)
      山田 唱,小宮山 貴将,大井 孝,平塚 貴子,服部 佳功
    • Organizer
      日本顎口腔機能学会第 63 回学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 地域高齢者の最大咬合力と死亡リスクに関する長期コホート研究:鶴ヶ谷プロジェクト2018

    • Author(s)
      大井 孝,小宮山貴将,坪井明人,遠又靖丈,辻 一郎,服部佳功.
    • Organizer
      日本老年歯科医学会第29回学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 認知機能障害を有する地域高齢者において主観的咀嚼能力と客観的咀嚼能力は乖離する2018

    • Author(s)
      小宮山貴将,大井 孝,平塚貴子,村上任尚,坪井明人,服部佳功.
    • Organizer
      日本補綴歯科学会第127回学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Nutrition contributes to the relationship between tooth loss and Mortality2018

    • Author(s)
      Hiratsuka T, Komiyama T, Ohi T, Tsuboi A, Tanji F, Tomata Y, Tsuji I, Watanabe M, Hattori Y.
    • Organizer
      96th General Session & Exhibition of the IADR
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2025-01-30  

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