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Consideration of effective skin care based on the relationship between skin barrier function and perceptional threshold

Research Project

Project/Area Number 18K10233
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 58050:Fundamental of nursing-related
Research InstitutionEhime University

Principal Investigator

Saeki Yuka  愛媛大学, 医学系研究科, 教授 (70211927)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2020: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords皮膚バリア機能 / 電流知覚閾値 / 疼痛閾値 / 経表皮水分蒸散量 / 皮膚温 / 角質水分量 / 皮膚知覚 / 知覚閾値 / 痛覚閾値 / 知覚過敏 / 角層水分量 / 医療用粘着テープ
Outline of Final Research Achievements

The purpose of this study was to clarify the relationship between skin barrier function and skin perceptual threshold. The skin barrier function was evaluated by measuring the transepidermal water loss (TEWL), and skin perceptual threshold by measuring the current perceptual threshold (CPT) and the pain threshold (PT). TEWL was deliberately altered by using 2% sodium lauryl sulfate solution on the palm side of the forearm. As a result, CPT and PT decrease as TEWL increased. In addition, TEWL and CPT or PT showed a significantly negative correlation. Therefore, it was concluded that hypersensitivity must occur when the skin barrier function is decreased.

Academic Significance and Societal Importance of the Research Achievements

アトピー性皮膚炎などでは皮膚バリア機能が低下しており、バリア機能の低下が長引くと掻痒など知覚にも影響を及ぼす。医療・介護現場では、乾燥した環境や医療用粘着テープの使用など、皮膚バリア機能が低下しやすい状況にある。さらに看護実践でよく行う清潔ケアでは、対象者の肌を直接刺激することが多い。しかしながら、対象者の皮膚感覚を考慮しながらケアを行うことはほとんどない。しかし、今後は皮膚バリア機能の状況を考慮しながらスキンケアを行う必要性を示した。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (17 results)

All 2021 2020 2019 2018

All Journal Article (7 results) (of which Peer Reviewed: 4 results,  Open Access: 2 results) Presentation (4 results) (of which Int'l Joint Research: 2 results) Book (6 results)

  • [Journal Article] 皮膚バリア機能に関わる要因と知覚閾値との関係.2021

    • Author(s)
      佐伯由香
    • Journal Title

      別冊Bio Clinica

      Volume: 10 Pages: 140-143

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Frequency, intensity, and partner of exercise habit is inversely associated with functional dyspepsia in young Japanese population.2021

    • Author(s)
      S. Furukawa, Y. Yamamoto, J. Watanabe, A. Kato, K. Kusumoto, E. Takeshita, Y. Ikeda, N. Yamamoto, K. Okada, K. Kohara, S. Saeki, Y. Saeki, Y. Hiasa
    • Journal Title

      Digestive Diseases and Sciences

      Volume: 21 Issue: 6 Pages: 2293-2298

    • DOI

      10.1007/s10620-021-07017-y

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Positive association between sleep disturbance and prevalence of functional dyspepsia in Japanese young people.2021

    • Author(s)
      Y. Yamamoto, S. Furukawa, J. Watanabe, A. Kato, K. Kusumoto, T. Miyake, E. Takeshita, Y. Ikeda, N. Yamamoto, K. Okada, K. Kohara, S. Saeki, Y. Saeki, Y. Hiasa
    • Journal Title

      Digestive Diseases and Sciences

      Volume: 21 Issue: 8 Pages: 3929-3937

    • DOI

      10.1007/s10620-021-07260-3

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 皮膚バリア機能と知覚閾値との関係2020

    • Author(s)
      佐伯由香
    • Journal Title

      Bio Clinica

      Volume: 9 Pages: 110-113

    • Related Report
      2020 Research-status Report
  • [Journal Article] 清拭後の皮膚バリア機能と知覚との関係2020

    • Author(s)
      佐伯由香
    • Journal Title

      Precision Medicine

      Volume: 3 Pages: 48-52

    • Related Report
      2019 Research-status Report
  • [Journal Article] Effect of scent of peppermint on work efficiency.2019

    • Author(s)
      Saeki Y,
    • Journal Title

      Complementary Alternative Medicine

      Volume: 2 Pages: 1-6

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] 集中力に及ぼすペパーミントの香りの効果2019

    • Author(s)
      佐伯由香
    • Journal Title

      AROMA RESEARCH

      Volume: 印刷中

    • NAID

      40022012174

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Presentation] Influence of intracranial bright light on the relationship between sleep and mood states in nurses working in two-shift system; A pilot study.2021

    • Author(s)
      Y. Saeki
    • Organizer
      Sigma’s 32nd International Nursing Research VIRTUAL Congress
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The relationship between sleep and mood states in nurses working in two-shift system.2020

    • Author(s)
      Saeki Y.
    • Organizer
      Sigma's Virtual 31st International Nursing Research Congress
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Influence of the scent of peppermint on concentration2018

    • Author(s)
      Saeki Yuka
    • Organizer
      29th International Nursing Research Congress
    • Related Report
      2018 Research-status Report
  • [Presentation] 不確実な時代における確かな看護-看護におけるサイエンスを考える2018

    • Author(s)
      佐伯由香
    • Organizer
      第38回日本看護科学学会学術集会
    • Related Report
      2018 Research-status Report
  • [Book] <改訂版>疾病の成立と回復促進2021

    • Author(s)
      岡田忍、佐伯由香、田城孝雄、山内豊明、長嶋洋治
    • Total Pages
      298
    • Publisher
      放送大学教育振興会
    • ISBN
      9784595322600
    • Related Report
      2021 Annual Research Report
  • [Book] イラストレイテッド生理学2021

    • Author(s)
      鯉渕典之、栗原敏、佐伯由香他
    • Total Pages
      662
    • Publisher
      丸善
    • ISBN
      9784621306079
    • Related Report
      2021 Annual Research Report
  • [Book] 改訂版 疾病の成立と回復促進2021

    • Author(s)
      岡田忍、佐伯由香他3名
    • Total Pages
      298
    • Publisher
      放送大学教育振興会
    • ISBN
      9784595322600
    • Related Report
      2020 Research-status Report
  • [Book] トートラ人体解剖生理学(第11版)2020

    • Author(s)
      佐伯由香、細谷安彦他23名
    • Total Pages
      670
    • Publisher
      丸善出版
    • ISBN
      9784621305393
    • Related Report
      2020 Research-status Report
  • [Book] 人体の構造と機能(第5版)2019

    • Author(s)
      内田さえ、佐伯由香、原田玲子
    • Total Pages
      407
    • Publisher
      医歯薬出版
    • Related Report
      2018 Research-status Report
  • [Book] トートラ人体の構造と機能(第5版)2019

    • Author(s)
      桑木共之、黒澤美枝子、佐伯由香、他26名
    • Total Pages
      1290
    • Publisher
      丸善出版
    • ISBN
      9784621303566
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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