| Project/Area Number |
18K10275
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 58060:Clinical nursing-related
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| Research Institution | Nagasaki University |
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Principal Investigator |
Kawashita Yumiko 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (10304958)
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| Project Period (FY) |
2018-04-01 – 2024-03-31
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| Project Status |
Completed (Fiscal Year 2023)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 頭頸部癌 / 放射線治療 / 口腔粘膜炎 / 口腔支持療法 / 口腔管理 / 支持療法 / 有害事象 / 頭頸部 / 予防バンドル / 頭頚部癌 |
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| Outline of Final Research Achievements |
Radiotherapy is a common treatment for head and neck cancer, and it is effective in preserving the shape and function of the affected area. However, radiotherapy can also result in adverse events, such as oral mucositis, taste disorders, and dry mouth. Oral mucositis, in particular, is a common side effect of radiotherapy, and it is important to practice oral management to prevent severe mucositis. Despite the importance of oral management, it has not yet been fully established. Therefore, I conducted studies to investigate the factors associated with severe mucositis and to identify effective strategies for preventing it.
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| Academic Significance and Societal Importance of the Research Achievements |
頭頸部への放射線治療によって口内炎をはじめとする癌治療の早期に生じる有害事象や放射線性口腔乾燥によって生じるむし歯の晩期の有害事象がある。そのため、本研究によって放射線治療前から口腔管理を行う方法が確立できれば、放射線治療の完遂と放射線治療後の晩期の有害事象を抑制することに貢献できると考えられる。さらに高齢者人口の増加に伴い、頭頸部癌で放射線治療を受ける患者が増えることから口腔管理の方法が確立することの社会的意義は大きいと考えられる。
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