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Effectiveness of Locomo25 score for exercise guidance aiming to prevent dementia

Research Project

Project/Area Number 18K10800
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionOsaka Kawasaki Rehabilitation University

Principal Investigator

Nakamura Misa  大阪河崎リハビリテーション大学, リハビリテーション学部, 教授 (70285386)

Co-Investigator(Kenkyū-buntansha) 今岡 真和  大阪河崎リハビリテーション大学, リハビリテーション学部, 講師 (40780961)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsロコモティブシンドローム / 認知機能 / ロコモ25 / 身体活動 / 地域在住高齢者 / コロナ禍 / フレイル / 口腔機能 / 転倒不安 / 運動機能 / 介入研究 / 地域高齢者 / 認知症 / 運動
Outline of Final Research Achievements

The aim of the study was to clarify the effectiveness of daily physical activity for cognitive function based on the presence or absence of locomotive syndrome (LS) in community-dwelling older persons. The LS group was 13.0%. After 13 weeks, cognitive function (ACE-R scores) were significantly higher in the>=2.29 than in the < 2.29 Ex (METs・h/day) group in the LS population based on two-way analysis of covariance. Furthermore, a significant increase in the ACE-R memory domain was seen in the >= 2.29 Ex group. These results suggest that >=2.29 Ex is important for improving cognitive function in LS populations with decreased locomotor function.

Academic Significance and Societal Importance of the Research Achievements

超高齢化社会において、要介護者増加の予防として認知症者の減少に向けた取り組みが必要である。認知機能低下の予防方法として、運動が広く提唱されている。しかしながら運動機能の程度と認知機能との関係についての報告は少なく、各個人の運動機能のレベルに合った指導の確立はなされていない。このような背景の中で本研究により、認知機能低下の予防を目的として運動または活動量の改善を開始する時期を決定するのに、ロコモ25スコアの低下が有用な指標となることが期待された。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (25 results)

All 2021 2020 2019

All Journal Article (11 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 11 results,  Open Access: 8 results) Presentation (14 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results)

  • [Journal Article] The beneficial effect of physical activity on cognitive function in community-dwelling older persons with locomotive syndrome2021

    • Author(s)
      Nakamura Misa、Imaoka Masakazu、Hashizume Hiroshi、Tazaki Fumie、Hida Mitsumasa、Nakao Hidetoshi、Omizu Tomoko、Kanemoto Hideki、Takeda Masatoshi
    • Journal Title

      PeerJ

      Volume: 9 Pages: e12292-e12292

    • DOI

      10.7717/peerj.12292

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between subjective oral dysfunction and locomotive syndrome in community-dwelling older adults2021

    • Author(s)
      Nakamura Misa、Imaoka Masakazu、Nakao Hidetoshi、Hida Mitsumasa、Tazaki Fumie、Imai Ryota、Utsunomiya Hirotoshi、Hashizume Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-021-92153-8

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased anxiety about falls and walking ability among community‐dwelling <scp>J</scp> apanese older adults during the <scp>COVID‐19</scp> pandemic2021

    • Author(s)
      Nakamura Misa、Imaoka Masakazu、Nakao Hidetoshi、Hida Mitsumasa、Imai Ryota、Tazaki Fumie、Takeda Masatoshi
    • Journal Title

      Psychogeriatrics

      Volume: 21 Issue: 5 Pages: 826-831

    • DOI

      10.1111/psyg.12750

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between cognitive decline and decreased serum osteocalcin levels in community-dwelling older people.2021

    • Author(s)
      Misa Nakamura, Masakazu Imaoka, Hiroshi Hashizume, Fumie Tazaki, Hidetoshi Nakao, Mitsumasa Hida, Tomoko Omizu, Hideki Kanemoto, Ichiro Kamei, Masatoshi Takeda
    • Journal Title

      Cognition and Rehabilitation

      Volume: 2 Pages: 220-226

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction of bone and brain: osteocalcin and cognition.2020

    • Author(s)
      Misa Nakamura, Masakazu Imaoka, Masatoshi Takeda
    • Journal Title

      International Journal of Neuroscience

      Volume: 25 Issue: 11 Pages: 1-9

    • DOI

      10.1080/00207454.2020.1770247

    • Related Report
      2020 Research-status Report 2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Association between cognitive function and body composition in community-dwelling older women.2020

    • Author(s)
      Misa Nakamura, Fumie Tazaki, Masakazu Imaoka, Hidetoshi Nakao, Mitsumasa Hida, Tomoko Omizu, Ryota Imai, Sachiko Nomura, Hirotoshi Utsunomiya, Masatoshi Takeda
    • Journal Title

      Cognition and Rehabilitation,

      Volume: 1 Pages: 35-42

    • NAID

      120007126778

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of the Characteristics and Duration of Chronic Pain on Psychosomatic Function in the Community-Dwelling Elderly Population.2020

    • Author(s)
      Hida M, Nakamura M, Imaoka M, Nakao H, Tasaki F, Omizu T, Takeda M, Ohnishi T, Wada C.
    • Journal Title

      Pain Res Manag.

      Volume: 7 Pages: 4714527-4714527

    • DOI

      10.1155/2020/4714527

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 地域在住高齢者の主観的健康感とフレイルとの関連について2020

    • Author(s)
      今岡真和、中村美砂、中尾英俊、田崎史江、生水智子、肥田光正、武田雅俊
    • Journal Title

      大阪河崎リハビリテーション大学紀要

      Volume: 14 Pages: 13-17

    • NAID

      120007125877

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 認知症プログラムに参加した高齢者のwell-beingのための園芸習慣のアンケート結果2020

    • Author(s)
      田崎史江、今岡真和、高野珠栄子、野村和樹、橋本雅至、中村美砂、村井恵、渡利純也、西阪亮洋、岡本聖也
    • Journal Title

      人間・植物関係学会雑誌

      Volume: 19 Pages: 1-10

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Teriparatide Improves Bone and Lipid Metabolism in a Male Rat Model of Type 2 Diabetes Mellitus.2019

    • Author(s)
      Nomura S, Kitami A, Takao-Kawabata R, Takakura A, Nakatsugawa M, Kono R, Maeno A, Tokuda A, Isogai Y, Ishizuya T, Utsunomiya H, Nakamura M.
    • Journal Title

      Endocrinology

      Volume: 160 Issue: 10 Pages: 2339-2352

    • DOI

      10.1210/en.2019-00239

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of Multicomponent Exercise and Nutrition Support on the Cognitive Function of Older Adults: A Randomized Controlled Trial.2019

    • Author(s)
      Imaoka M, Nakao H, Nakamura M, Tazaki F, Maebuchi M, Ibuki M, Takeda M.
    • Journal Title

      Clin Interv Aging

      Volume: 11 Pages: 2145-2153

    • DOI

      10.2147/cia.s229034

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 地域在住高齢者における主観的口腔機能とロコモティブシンドロームの関係2021

    • Author(s)
      中村美砂、今岡真和、中尾英俊、肥田光正、田崎史江、今井亮太、武田雅俊
    • Organizer
      第28回日本未病学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 認知症予防をめざした身体活動量改善のためのロコモ25の有用性.2020

    • Author(s)
      中村美砂, 今岡真和, 田崎史江, 中尾英俊, 肥田光正, 野村幸子, 武田雅俊
    • Organizer
      日本未病学会 (オンライン開催)
    • Related Report
      2020 Research-status Report
  • [Presentation] 地域在住高齢者のロコモティブシンドローム項目と歩行速度との関係.2020

    • Author(s)
      野村幸子, 今岡真和, 中尾英俊, 肥田光正, 今井亮太, 宇都宮洋才, 中村美砂
    • Organizer
      日本未病学会 (オンライン開催)
    • Related Report
      2020 Research-status Report
  • [Presentation] Association between cognitive function and body mass in community-dwelling elderly women in Japan.2019

    • Author(s)
      Misa Nakamura, Masakazu Imaoka, Fumie Tazaki, Taeko Takano, Kazuki Nomura, Ichiro Kamei, Masatoshi Takeda
    • Organizer
      Euro Aging 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact on physical and mental health in community-dwelling elderly population.2019

    • Author(s)
      Mitsumasa Hida, Masakazu Imaoka, Hidetoshi Nakao, Misa Nakamura, Tomoko Omizu, Fumie Tazaki, Masatoshi Takeda, Katsumi Hamaoka
    • Organizer
      13th International Society of Physical and Rehabilitation Medicine(ISPRM 2019)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of multicomponent exercise and nutrition support on the cognitive function of older adults: A randomized controlled trial.2019

    • Author(s)
      Masakazu Imaoka, Misa Nakamura, Hidetoshi Nakao, Fumie Tazaki, Motohiro Maebuchi, Masahisa Ibuki
    • Organizer
      13th International Society of Physical and Rehabilitation Medicine(ISPRM 2019)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Pre-sarcopenia/sarcopenia revert rates of participants in a three-month exercise class.2019

    • Author(s)
      Masakazu Imaoka, Misa Nakamura, Hidetoshi Nakao, Fumie Tazaki
    • Organizer
      13th International Society of Physical and Rehabilitation Medicine(ISPRM 2019)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Relationship between horticultural activities and sleep status among older adults living in a community: A questionnaire analysis and a fact-finding survey related to sleep2019

    • Author(s)
      Tomoko Omizu, Fumie Tazaki, Misa Nakamura, Masakazu Imaoka, Hidetoshi Nakao, Mitsumasa Hida
    • Organizer
      SPPR-JHTA Joint International Symposium & 2019 Annual Meeting
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 地域在住高齢者の認知機能の推移と血中骨代謝関連物質の変化量との関係.2019

    • Author(s)
      中村美砂, 今岡真和, 田崎史江, 中尾英俊, 肥田光正, 生水智子, 武田雅俊
    • Organizer
      第26回日本未病システム学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 地域在住高齢者の主観的健康感とフレイルとの関連について.2019

    • Author(s)
      今岡真和, 中村美砂, 田崎史江, 中尾英俊
    • Organizer
      第21回日本骨粗鬆症学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 地域在住高齢者のプレフレイルと就労との関連について.2019

    • Author(s)
      今岡真和, 中村美砂, 中尾英俊, 田崎史江, 生水智子, 肥田光正, 武田雅俊, 樋口由美
    • Organizer
      第6回地域理学療法学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 地域在住高齢者の慢性疼痛の有無ならびに保有期間と心理機能との関係2019

    • Author(s)
      肥田光正, 中村美砂, 今岡真和, 中尾英俊, 田崎史江, 生水智子, 和田親宗, 大西忠輔, 山坂宏太, 武田雅俊.
    • Organizer
      第3回リハビリテーション医学会秋季学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] Physical activity and body composition on cognitive function.2019

    • Author(s)
      Misa Nakamura
    • Organizer
      Asia Pasific Regional Congress of Biological Psyciatry
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 地域在住高齢者の認知機能と体組成との関係2019

    • Author(s)
      中村美砂、今岡真和、田崎史江、高野珠栄子、野村和樹、武田雅俊
    • Organizer
      第25回日本未病システム学会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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