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Detailed pattern of physical activity/sedentary behavior and cognitive decline among older adults: a cohort study

Research Project

Project/Area Number 18K10829
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionTokyo Medical University

Principal Investigator

Kikuchi Hiroyuki  東京医科大学, 医学部, 講師 (90783142)

Co-Investigator(Kenkyū-buntansha) 井上 茂  東京医科大学, 医学部, 教授 (00349466)
村山 洋史  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長 (00565137)
菖蒲川 由郷  新潟大学, 医歯学総合研究科, 特任教授 (30621198)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords認知機能低下 / 地域在住高齢者 / 疫学研究 / 身体活動パターン / 加速度計 / 高齢者 / 座位行動 / 身体活動 / コホート研究
Outline of Final Research Achievements

This study is a longitudinal study to investigate the longitudinal association between objectively-measured physical activity and cognitive function among 537 older adults living in Tokamachi City, Niigata Prefecture. Within the period of this study, the following findings were published in an international journal: (1) moderate-to-vigorous physical activity (MVPA) is related to cognitive function, (2) MVPA time is related to hippocampal volume, and (3) frailty in the elderly is related to duration of sedentary activity lasting 30 minutes or longer. On the other hand, the longitudinal analysis was not completed because the follow-up survey was delayed due to COVID-19. We plan to conduct these analyses as soon as the longitudinal data are fixed.

Academic Significance and Societal Importance of the Research Achievements

認知機能の低下は、高齢者の主要な健康課題の一つである。身体活動は、適切な介入等によって増やすことが可能であり、高齢者の認知症・認知機能低下の予防戦略上、重要である。本研究は、認知機能低下に中高強度身体活動が重要であることが示唆された。この成果は、高齢者の認知機能低下を予防するためには、中高強度身体活動を含む介入が有効である可能性を示唆するものである。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (13 results)

All 2022 2021 2020 2019 2018

All Journal Article (8 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 8 results,  Open Access: 8 results) Presentation (5 results)

  • [Journal Article] Objectively Measured Intensity-specific Physical Activity and Hippocampal Volume Among Community-dwelling Older Adults2022

    • Author(s)
      Machida Masaki、Takamiya Tomoko、Amagasa Shiho、Murayama Hiroshi、Fujiwara Takeo、Odagiri Yuko、Kikuchi Hiroyuki、Fukushima Noritoshi、Kouno Mitsuo、Saito Yu、Yoshimine Fumitoshi、Inoue Shigeru、Shobugawa Yugo
    • Journal Title

      Journal of Epidemiology

      Volume: 32 Issue: 11 Pages: 489-495

    • DOI

      10.2188/jea.JE20200534

    • NAID

      130007997862

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2022-11-05
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Associations of older adults' physical activity and bout-specific sedentary time with frailty status: Compositional analyses from the NEIGE study2021

    • Author(s)
      Kikuchi Hiroyuki、Inoue Shigeru、Amagasa Shiho、Fukushima Noritoshi、Machida Masaki、Murayama Hiroshi、Fujiwara Takeo、Chastin Sebastien、Owen Neville、Shobugawa Yugo
    • Journal Title

      Experimental Gerontology

      Volume: 143 Pages: 111149-111149

    • DOI

      10.1016/j.exger.2020.111149

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Associations of Sedentary and Physically-Active Behaviors With Cognitive-Function Decline in Community-Dwelling Older Adults: Compositional Data Analysis From the NEIGE Study2020

    • Author(s)
      Amagasa Shiho、Inoue Shigeru、Murayama Hiroshi、Fujiwara Takeo、Kikuchi Hiroyuki、Fukushima Noritoshi、Machida Masaki、Chastin Sebastien、Owen Neville、Shobugawa Yugo
    • Journal Title

      Journal of Epidemiology

      Volume: 30 Issue: 11 Pages: 503-508

    • DOI

      10.2188/jea.JE20190141

    • NAID

      130007936920

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2020-11-05
    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Changes in rural older adults' sedentary and physically-active behaviors between a non-snowfall and a snowfall season: Compositional analysis from the NEIGE study2020

    • Author(s)
      Amagasa Shiho、Inoue Shigeru、Murayama Hiroshi、Fujiwara Takeo、Kikuchi Hiroyuki、Fukushima Noritoshi、Machida Masaki、Chastin Sebastien、Owen Neville、Shobugawa Yugo
    • Journal Title

      BMC Public Health

      Volume: 20 Issue: 1 Pages: 1248-1248

    • DOI

      10.1186/s12889-020-09343-8

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Intensity-specific validity and reliability of the Japan Public Health Center-based prospective study-physical activity questionnaire2020

    • Author(s)
      Kikuchi Hiroyuki、Inoue Shigeru、Odagiri Yuko、Ihira Hikaru、Inoue Manami、Sawada Norie、Noda Mitsuhiko、Tsugane Shoichiro
    • Journal Title

      Preventive Medicine Reports

      Volume: 20 Pages: 101169-101169

    • DOI

      10.1016/j.pmedr.2020.101169

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of accelerometer-measured sedentary behavior, and light- and moderate-to-vigorous-intensity physical activity in white- and blue-collar workers in a Japanese manufacturing plant2018

    • Author(s)
      Fukushima Noritoshi、Kitabayashi Makiko、Kikuchi Hiroyuki、Sasai Hiroyuki、Oka Koichiro、Nakata Yoshio、Tanaka Shigeho、Inoue Shigeru
    • Journal Title

      Journal of Occupational Health

      Volume: 60 Issue: 3 Pages: 246-253

    • DOI

      10.1539/joh.2017-0276-OA

    • NAID

      130006744237

    • ISSN
      1341-9145, 1348-9585
    • Year and Date
      2018-05-20
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Objectively measured neighborhood walkability and change in physical activity in older Japanese adults: A five-year cohort study2018

    • Author(s)
      Kikuchi Hiroyuki、Nakaya Tomoki、Hanibuchi Tomoya、Fukushima Noritoshi、Amagasa Shiho、Oka Koichiro、Sallis James、Inoue Shigeru
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 15 Issue: 9 Pages: 1814-1814

    • DOI

      10.3390/ijerph15091814

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Drivers are more physically active than non-drivers in older adults2018

    • Author(s)
      Amagasa Shiho、Fukushima Noritoshi、Kikuchi Hiroyuki、Takamiya Tomoko、Odagiri Yuko、Oka Koichiro、Inoue Shigeru
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 15 Issue: 6 Pages: 1094-1094

    • DOI

      10.3390/ijerph15061094

    • URL

      https://pure.teikyo.jp/en/publications/4b3f3bd7-4386-4618-bd91-eb66423f5194

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 農村部在住高齢者における睡眠、座位行動、身体活動の関連要因:NEIGE study2020

    • Author(s)
      天笠志保、井上茂、村山洋史、藤原武男、菊池宏幸、福島教照、町田征己、菖蒲川由郷
    • Organizer
      第30回 日本疫学会学術総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 豪雪地域在住高齢者における非積雪期と積雪期の加速度計で評価した身体活動パターンの比較:NEIGE study ~Compositional data analysisを用いた縦断研究~2019

    • Author(s)
      天笠志保、井上茂、村山洋史、藤原武男、菊池宏幸、福島教照、町田征己、菖蒲川由郷
    • Organizer
      第22回 日本運動疫学会学術総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 農村部高齢者における加速度計で評価した身体活動パターンの性差: NEIGE study2019

    • Author(s)
      天笠志保、井上茂、福島教照、菊池宏幸、町田征己、村山洋史、藤原武男、菖蒲川由郷
    • Organizer
      第29回日本疫学会学術総会
    • Related Report
      2018 Research-status Report
  • [Presentation] 国際標準化身体活動質問票(選択肢版)の開発と妥当性の検討2018

    • Author(s)
      菊池宏幸、福島教照、町田征己、天笠志保、井上茂
    • Organizer
      第182回 東京医科大学医学会総会
    • Related Report
      2018 Research-status Report
  • [Presentation] 農作業と高齢者の身体活動パターンの関連: NEIGE study2018

    • Author(s)
      天笠志保、井上茂、福島教照、菊池宏幸、町田征己、村山洋史、藤原武男、菖蒲川由郷
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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