| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Our brains predict the consequences of its own movements and contribute to minimize a forthcoming disturbance; the feedforward postural controls have been addressed as anticipatory postural adjustments. We compared postural reactions to repetitive perturbations in cerebellar-lesioned rats with those of controls using a classical conditioning paradigm. The conditioning stimulus that consisted of an visual cue preceded the unconditioned stimulus that consisted of tilting of the platform during bipedal standing in rat. During conditioning, control rats established conditioned postural responses. However, the cerebellar-lesioned rats were unable to acquire the conditioned postural reactions. A posture control model based on the internal model was constructed and evaluated by comparison with the results of behavioral data. The results suggested that the postural control with learning in the cerebellum can be explained by the anticipatory control based on the internal model.
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