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Does neuromodulation recover central fatigue ?

Research Project

Project/Area Number 18K10970
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59030:Physical education, and physical and health education-related
Research InstitutionUekusa Gakuen University

Principal Investigator

Endoh Takashi  植草学園大学, 発達教育学部, 准教授 (80510594)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsニューロモデュレーション / 中枢性疲労 / 経頭蓋直流電流刺激 / 運動パフォーマンス / 皮質運動野 / 運動制御 / 疲労回復
Outline of Final Research Achievements

This study attempted to investigate whether neuromodulation could induce recovery of central fatigue after high-intensity exercise and elucidate the underlying mechanism. After performing a fatigue task with maximal effort knee extension, neuromodulation with transcranial direct current stimulation, which can modulate motor cortical excitability, led to recovery of sprint cycling performance. Therefore, neuromodulation can optimize motor cortical excitability and recover central fatigue induced by high-intensity exercise.

Academic Significance and Societal Importance of the Research Achievements

脳の興奮性を変化させるニューロモデュレーションを用いて高強度運動で低下した運動パフォーマンスを回復できる可能性を示したことが、本研究による新たな知見である。この研究を更に進めることで、早期の疲労の回復が求められるスポーツやリハビリテーションなどの分野における画期的な疲労回復方法の開発に繋がることが予測される。また、中枢性疲労の回復において、皮質運動野の興奮性の修飾が有効である可能性を示したことは、未解明な点の多い中枢性疲労の機序ならびに機能的意義においても学術的インパクトのある知見であると考えられる。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (5 results)

All 2021 2020 2018

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (4 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Differential effects of transcranial direct current stimulation on sprint and endurance cycling2020

    • Author(s)
      Syusaku Sasada, Takashi Endoh, Tomoya Ishii, Kazuma Kawashima, Shuta Sato, Akifumi Hayashi, Tomoyoshi Komiyama
    • Journal Title

      Translational Sports Medicine

      Volume: 3 Issue: 3 Pages: 204-212

    • DOI

      10.1002/tsm2.129

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 脊髄直流電気刺激による サイクリング中の総腓骨神経反射振幅増大2021

    • Author(s)
      笹田周作、石井智也、遠藤隆志、中島剛、小宮山伴与志
    • Organizer
      第29回日本運動生理学会大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 脊髄直流電流刺激による不随意なサイクリングケイデンスの上昇2018

    • Author(s)
      笹田周作、石井智也、遠藤隆志、小宮山伴与志
    • Organizer
      第26回日本運動生理学会大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 脊髄直流電流刺激によるサイクリング移送依存的な皮膚反射の修飾2018

    • Author(s)
      笹田周作、石井智也、遠藤隆志、中島剛、小宮山伴与志
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Involuntary changes in leg cycling cadence following transcutaneous spinal direct stimulation2018

    • Author(s)
      Syusaku Sasada, Takashi Endoh, Tomoya Ishii, Kazuma. Kawashima, Shuta. Sato, Akira. Hayashi, Tomoyoshi Komiyama
    • Organizer
      Neuroscience 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-04-23   Modified: 2023-01-30  

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