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Clinical research in sarcopenic dypshagia

Research Project

Project/Area Number 18K11142
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59040:Nutrition science and health science-related
Research InstitutionNational Center for Geriatrics and Gerontology (2020)
Aichi Medical University (2018-2019)

Principal Investigator

Maeda Keisuke  国立研究開発法人国立長寿医療研究センター, 病院, 医長 (50775179)

Co-Investigator(Kenkyū-buntansha) 森 直治  愛知医科大学, 医学部, 教授 (70625540)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords摂食嚥下障害 / サルコペニア / 低栄養 / フレイル / リハビリテーション / 急性期病院
Outline of Final Research Achievements

We conducted a study to find out the prevalence, risk factors, and possible ways to treat the disorder of eating function caused by muscle deterioration due to aging and various other reasons (sarcopenic dysphgaia). We have published 14 papers in English and many research results in public. Nutrition-related problems such as undernutrition, low muscle function, and low muscle mass were etiologies of this disease. We showed that nutritional interventions could contribute to recovery from this disease. All of the research findings were considered to be beneficial in solving the eating problems of the elderly.

Academic Significance and Societal Importance of the Research Achievements

サルコペニアの摂食嚥下障害は2011年以来、本邦を中心に発せられた新しい摂食嚥下障害の病因である。高齢者や要介護者の多くにこの新しい摂食嚥下障害がみられることがわかり、従来のリハビリテーションだけでは十分な回復に導けない可能性を見出した。高齢者の摂食嚥下障害への介入方法にパラダイムシフトが起こる可能性がある。食べることは生きること及び幸福感の源である。この新しいモデルの摂食嚥下障害予防や治療法を確立することにつながり非常に価値がある研究となった。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (47 results)

All 2021 2020 2019

All Journal Article (13 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 12 results,  Open Access: 6 results) Presentation (30 results) (of which Int'l Joint Research: 8 results,  Invited: 9 results) Book (4 results)

  • [Journal Article] Assessing skeletal muscle mass based on the cross-sectional area of muscles at the 12th thoracic vertebra level on computed tomography in patients with oral squamous cell carcinoma2021

    • Author(s)
      Matsuyama Remi、Maeda Keisuke、Yamanaka Yosuke、Ishida Yuria、Kato Ryoko、Nonogaki Tomoyuki、Shimizu Akio、Ueshima Junko、Kazaoka Yoshiaki、Hayashi Tomio、Ito Kunihiro、Furuhashi Akifumi、Ono Takayuki、Mori Naoharu
    • Journal Title

      Oral Oncology

      Volume: 113 Pages: 105126-105126

    • DOI

      10.1016/j.oraloncology.2020.105126

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nutritional Management Enhances the Recovery of Swallowing Ability in Older Patients with Sarcopenic Dysphagia2021

    • Author(s)
      Shimizu Akio、Fujishima Ichiro、Maeda Keisuke、Wakabayashi Hidetaka、Nishioka Shinta、Ohno Tomohisa、Nomoto Akiko、Kayashita Jun、Mori Naoharu、The Japanese Working Group on Sarcopenic Dysphagia
    • Journal Title

      Nutrients

      Volume: 13 Issue: 2 Pages: 596-596

    • DOI

      10.3390/nu13020596

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The SARC-F Score on Admission Predicts Falls during Hospitalization in Older Adults2021

    • Author(s)
      Ishida Y.、Maeda Keisuke、Ueshima J.、Shimizu A.、Nonogaki T.、Kato R.、Matsuyama R.、Yamanaka Y.、Mori N.
    • Journal Title

      The journal of nutrition, health & aging

      Volume: 25 Issue: 3 Pages: 399-404

    • DOI

      10.1007/s12603-021-1597-3

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calf circumference value for sarcopenia screening among older adults with stroke2021

    • Author(s)
      Inoue Tatsuro、Maeda Keisuke、Shimizu Akio、Nagano Ayano、Ueshima Junko、Sato Keisuke、Murotani Kenta
    • Journal Title

      Archives of Gerontology and Geriatrics

      Volume: 93 Pages: 104290-104290

    • DOI

      10.1016/j.archger.2020.104290

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Impact of geniohyoid and masseter muscle masses on dysphagia after salvage surgery and radiotherapy in head and neck cancer2021

    • Author(s)
      Hashida Nao、Shamoto Hiroshi、Maeda Keisuke、Wakabayashi Hidetaka
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 2278-2278

    • DOI

      10.1038/s41598-021-82039-0

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of Sarcopenic Dysphagia with Underlying Sarcopenia Following Hip Fracture Surgery in Older Women2020

    • Author(s)
      Nagano Ayano、Maeda Keisuke、Shimizu Akio、Nagami Shinsuke、Takigawa Naohide、Ueshima Junko、Suenaga Masaki
    • Journal Title

      Nutrients

      Volume: 12 Issue: 5 Pages: 1365-1365

    • DOI

      10.3390/nu12051365

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimating appendicular muscle mass in older adults with consideration on paralysis2020

    • Author(s)
      Ueshima Junko、Maeda Keisuke、Murotani Kenta、Shimizu Akio、Nagano Ayano、Sato Keisuke、Ishida Yuria、Mori Naoharu、Suenaga Masaki
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 20 Issue: 12 Pages: 1145-1150

    • DOI

      10.1111/ggi.14056

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Physical Rehabilitation and Nutritional Intake Management on Improvement in Tongue Strength in Sarcopenic Patients2020

    • Author(s)
      Nagano Ayano、Maeda Keisuke、Koike Masaki、Murotani Kenta、Ueshima Junko、Shimizu Akio、Inoue Tatsuro、Sato Keisuke、Suenaga Masaki、Ishida Yuria、Mori Naoharu
    • Journal Title

      Nutrients

      Volume: 12 Issue: 10 Pages: 3104-3104

    • DOI

      10.3390/nu12103104

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Formula for the Cross-Sectional Area of the Muscles of the Third Lumbar Vertebra Level from the Twelfth Thoracic Vertebra Level Slice on Computed Tomography2020

    • Author(s)
      Ishida Yuria、Maeda Keisuke、Yamanaka Yosuke、Matsuyama Remi、Kato Ryoko、Yamaguchi Makoto、Nonogaki Tomoyuki、Shimizu Akio、Ueshima Junko、Murotani Kenta、Mori Naoharu
    • Journal Title

      Geriatrics

      Volume: 5 Issue: 3 Pages: 47-47

    • DOI

      10.3390/geriatrics5030047

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] SARC-F as a Screening Tool for Sarcopenia and Possible Sarcopenia Proposed by AWGS 2019 in Hospitalized Older Adults2020

    • Author(s)
      Ishida Y.、Maeda Keisuke、Nonogaki T.、Shimizu A.、Yamanaka Y.、Matsuyama R.、Kato R.、Ueshima J.、Murotani K.、Mori N.
    • Journal Title

      The journal of nutrition, health & aging

      Volume: 24 Issue: 10 Pages: 1053-1060

    • DOI

      10.1007/s12603-020-1462-9

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Burden of Premorbid Consumption of Texture Modified Diets in Daily Life on Nutritional Status and Outcomes of Hospitalization2019

    • Author(s)
      Maeda K, Ishida Y, Nonogaki T, Shimizu A, Yamanaka Y, Matsuyama R, Kato R, Mori N
    • Journal Title

      J Nutr Health Aging

      Volume: 23 Issue: 10 Pages: 973-978

    • DOI

      10.1007/s12603-019-1237-3

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Development and Predictors of Sarcopenic Dysphagia during Hospitalization of Older Adults2019

    • Author(s)
      Maeda Keisuke、Ishida Yuria、Nonogaki Tomoyuki、Shimizu Akio、Yamanaka Yosuke、Matsuyama Remi、Kato Ryoko、Mori Naoharu
    • Journal Title

      Nutrients

      Volume: 12 Issue: 1 Pages: 70-70

    • DOI

      10.3390/nu12010070

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Global Leadership Initiative on Malnutrition-Defined Malnutrition Predicts Prognosis in Persons With Stroke-Related Dysphagia2019

    • Author(s)
      Shimizu A, Maeda K, Koyanagi Y, Kayashita J, Fujishima I, Mori N.
    • Journal Title

      J Am Med Dir Assoc.

      Volume: 20(12) Issue: 12 Pages: 1628-1633

    • DOI

      10.1016/j.jamda.2019.07.008

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Risk factors and therapeutic strategies for sarcopenic dysphagia, a new etiology of dysphagia of older adults2021

    • Author(s)
      Keisuke Maeda
    • Organizer
      6th Geriatric Innovation Forum
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 高齢脳卒中患者におけるAWGS 2019推奨の下腿周径カットオフ値の妥当性の検討2020

    • Author(s)
      井上 達朗, 前田 圭介, 清水 昭雄, 永野 彩乃, 上島 順子, 佐藤 圭佑, 室谷 健太
    • Organizer
      第10回日本リハビリテーション栄養学会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 加齢および疾患による呼吸筋サルコペニアと悪循環 ナラティブレビュー2020

    • Author(s)
      宮崎 慎二郎, 永野 彩乃, 若林 秀隆, 前田 圭介, 小蔵 要司, 森 隆志, 藤原 大
    • Organizer
      第10回日本リハビリテーション栄養学会学術集会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 呼吸筋サルコペニアとサルコペニア性呼吸障害 定義・診断・介入2020

    • Author(s)
      永野 彩乃, 若林 秀隆, 前田 圭介, 小蔵 要司, 宮崎 慎二郎, 森 隆志, 藤原 大
    • Organizer
      第10回日本リハビリテーション栄養学会学術集会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Development of appendicular muscle mass estimating formulas for older adults considering paralysis2020

    • Author(s)
      Junko Ueshima, Keisuke Maeda, Kenta Murotani; Akio Shimizu, Ayano Nagano, Keisuke Sato, Yuria Ishida, Naoharu Mori and Masaki Suenaga
    • Organizer
      13th international SCWD digital conference on cachexia, sarcopenia and muscle wasting
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] SARC-F Questionnaire score is Associated with Mortality of Cancer Patients Receiving Palliative Care2020

    • Author(s)
      Naoharu Mori, Keisuke Maeda, Yuria Ishida, Tomoyuki Nonogaki, Akio Shimizu, Yosuke Yamanaka, Remi Matsuyama, Ryoko Kato, Junko Ueshima,
    • Organizer
      13th international SCWD digital conference on cachexia, sarcopenia and muscle wasting
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The validity of SARC-F on screening sarcopenia defined by AWGS 2019 in hospitalized older adults2020

    • Author(s)
      Keisuke Maeda,Yuria Ishida,Tomoyuki Nonogaki,Akio Shimizu,Yosuke Yamanaka,Remi Matsuyama,Ryoko Kato,Junko Ueshima,Kenta Murotani,Naoharu Mori
    • Organizer
      13th international SCWD digital conference on cachexia, sarcopenia and muscle wasting
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] NSTでのフレイル・サルコペニア対策2020

    • Author(s)
      前田圭介
    • Organizer
      第7回日本サルコペニア・フレイル学会大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Tongue strength and swallowing function improve through nutritional management in sarcopenic older adults undergoing rehabilitation2020

    • Author(s)
      Keisuke Maeda, Ayano Nagano, Kenta Murotani, Junko Ueshima, Akio Shimizu, Tatsuro Inoue, Keisuke Sato, Yuria Ishida, Naoharu Mori
    • Organizer
      6th Asian Conference for Frailty & Sarcopenia 2020
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Calf circumference value for sarcopenia screening among older adults with stroke2020

    • Author(s)
      Tatsuro Inoue,Keisuke Maeda,Akio Shimizu,Ayano Nagano,Junko Ueshima,Keisuke Sato,Kenta Murotani
    • Organizer
      6th Asian Conference for Frailty & Sarcopenia 2020
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 施設入居高齢者のGLIM基準で診断した低栄養有病率と食事形態の関連性2020

    • Author(s)
      神山 佐奈美, 麻植 有希子, 百瀬 由香梨, 山田 絵里加, 前田 圭介
    • Organizer
      第62回日本老年医学会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] サルコペニアの嚥下障害~高齢者モデルで考える新しいetiology~2020

    • Author(s)
      前田圭介
    • Organizer
      第62回日本老年医学会学術集会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] GLIM基準低栄養は高齢大腿骨近位部骨折患者の不良な機能的帰結を予測する2019

    • Author(s)
      清水 昭雄, 前田 圭介, 石田 優利亜, 森 直治
    • Organizer
      日本リハビリテーション栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 脳卒中リハビリテーション患者の嚥下障害と栄養状態の関連性について2019

    • Author(s)
      ブラウン 章子, 前田 圭介, 平良 康子, 大城 あゆみ, 島 由香, 北川 よう, 翁長 安李, 佐藤 圭祐, 吉田 貞夫, 末永 正機
    • Organizer
      日本リハビリテーション栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 急性期病院入院高齢者における栄養とサルコペニアの関連性 の検討2019

    • Author(s)
      前田圭介, 石田優利亜, 濱崎友紀子, 藤田翔一, 井上寿味子, 柴田裕紀, 嵐山祐介, 加藤泰子, 佐藤義明, 松原奈緒, 木下功, 野々垣知行, 笹川文, 森直治
    • Organizer
      日本ヒューマンヘルスケア学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 令和元年はサルコペニアの摂食嚥下障害元年2019

    • Author(s)
      前田圭介
    • Organizer
      日本摂食嚥下リハビリテーション学会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 嚥下調整食摂取患者の栄養状態とサルコペニア有病率2019

    • Author(s)
      ブラウン 章子, 平良 康子, 末永 正機, 前田 圭介
    • Organizer
      日本摂食嚥下リハビリテーション学会
    • Related Report
      2019 Research-status Report
  • [Presentation] REFERENCE OF MALNUTRITION PREVALENCE DIAGNOSED ACCORDING TO GLOBAL LEADERSHIP INITIATIVE ON MALNUTRITION CRITERIA IN THE ELDERLY REQUIRING CARE IN JAPAN2019

    • Author(s)
      Y. Oe, S. Kohyama, K. Maeda
    • Organizer
      ESPEN Congress
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] オーラルフレイル・摂食嚥下リハビリテーションと老年栄養2019

    • Author(s)
      前田圭介
    • Organizer
      日本腎臓リハビリテーション学会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 入院中に発症する摂食嚥下障害にはサルコペニアが関連する2019

    • Author(s)
      前田圭介
    • Organizer
      日本サルコペニア・フレイル学会
    • Related Report
      2019 Research-status Report
  • [Presentation] サルコペニアの摂食嚥下障害と栄養ケア2019

    • Author(s)
      前田圭介
    • Organizer
      日本神経筋疾患摂食・嚥下・栄養研究会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] Prevalence of malnutrition based on GLIM criteria in hospitalized older adults2019

    • Author(s)
      K. Maeda, Y. Ishida, T. Nonogaki, N. Mori
    • Organizer
      The 20th Congress of Parenteral and Enteral Nutrition Society of Asia
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 急性期脳卒中患者における低栄養と摂食嚥下障害回復の関連2019

    • Author(s)
      石田 優利亜, 前田 圭介, 清水 昭雄
    • Organizer
      日本摂食嚥下リハビリテーション学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 脳梗塞リハビリテーション患者の骨格筋減少と機能的予後との関連2019

    • Author(s)
      佐藤圭祐、前田圭介
    • Organizer
      日本静脈経腸栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 回復期リハ病棟におけるKTバランスチャートの有用性について2019

    • Author(s)
      和座雅浩、前田圭介、河合克尚、山本正彦、磯野倫夫
    • Organizer
      日本静脈経腸栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 回復期リハビリテーション病棟における大腿骨近位部骨折患者の摂取エネルギーと日常生活活動改善との関連2019

    • Author(s)
      梅澤浩輝、安部聡子、小蔵要司、鈴木千衣子、西田明子、内山喜重、前田圭介、若林秀隆、百崎良
    • Organizer
      日本静脈経腸栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] サルコペニアの摂食嚥下障害患者における摂食嚥下リハビリテーション治療効果の検討2019

    • Author(s)
      石河ゆかり、影山康太、佐藤晴香、大内健史、森隆志、池谷進、社本博、前田圭介、若林秀隆
    • Organizer
      日本静脈経腸栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 脳卒中後嚥下障害患者の入院時栄養失調リスクは退院時嚥下機能と関連した2019

    • Author(s)
      清水昭雄,前田圭介,藤島一郎,小柳雄一,栢下淳
    • Organizer
      日本静脈経腸栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 嚥下調整食の栄養価に配慮した栄養管理の必要性2019

    • Author(s)
      前田 圭介,奥田優利亜,木下 功,野々垣知行,工藤すみ,嵐山裕介,井上寿味子,加藤泰子,佐藤義明,柴田裕紀,濱崎友紀子,藤田翔一,伊藤邦弘,藤田 建,早川俊彦,森 直治
    • Organizer
      日本静脈経腸栄養学会
    • Related Report
      2019 Research-status Report
  • [Presentation] リハビリテーション患者のリハ栄養~筋量維持か強化か~2019

    • Author(s)
      前田圭介
    • Organizer
      日本病態栄養学会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Book] Aspiration Pneumonia The Current Clinical Giant for Respiratory Physicians2020

    • Author(s)
      Keisuke Maeda
    • Total Pages
      239
    • Publisher
      Springer
    • Related Report
      2020 Annual Research Report
  • [Book] 診療室ではじめよう! 口腔機能管理と栄養指導2020

    • Author(s)
      上田 貴之、大久保 真衣、立木 千恵、前田 圭介、柳沢 幸恵
    • Total Pages
      132
    • Publisher
      永末書店
    • ISBN
      9784816013768
    • Related Report
      2019 Research-status Report
  • [Book] 臨床研究アウトプット術2020

    • Author(s)
      前田圭介,室谷健太
    • Total Pages
      386
    • Publisher
      中外医学社
    • ISBN
      9784498048782
    • Related Report
      2019 Research-status Report
  • [Book] 「攻めの栄養療法」実践マニュアル : うまくいく栄養改善と生活機能改善2019

    • Author(s)
      前田 圭介、若林 秀隆、西岡 心大
    • Total Pages
      238
    • Publisher
      中外医学社
    • ISBN
      9784498018020
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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