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Investigation on brain networks in task processing based on dissipation from default modes

Research Project

Project/Area Number 18K11450
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 61030:Intelligent informatics-related
Research InstitutionFukui University of Technology

Principal Investigator

Yamanishi Teruya  福井工業大学, 環境情報学部, 教授 (50298387)

Co-Investigator(Kenkyū-buntansha) 高橋 哲也  福井大学, 学術研究院医学系部門, 客員准教授 (00377459)
信川 創  千葉工業大学, 情報科学部, 准教授 (70724558)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords脳波 / デフォルトモード / 同期の逸脱 / 数字想起 / アルツハイマー型認知症 / 機械学習 / 脳領野間のネットワーク / 経験的モード分解 / 脳領野のネットワーク / 脳磁波 / 脳内ネットワーク / 脳信号の同期性 / 同期の散逸
Outline of Final Research Achievements

This study is to classify the machine in EEG analysis. At first, open data (3 electrodes) of event-related potential EEG with numbers from 1 to 9 were analyzed using Multiscale Entropy as a measure of complexity, and Gaussian process regression was performed for each subject to calculate the regression loss. Then, all subjects were found to have the potential to discriminate visibility at any one electrode. Next, we classified cognitive severity and mildness based on EEG of Alzheimer's disease. The Phase Lag Index as a measure of synchrony was calculated from 16-electrode measurements, and a combination of electrode-specific arithmetic mean and the t-SNE method was found to significantly improve the classification loss value.

Academic Significance and Societal Importance of the Research Achievements

事象関連電位の3電極脳波で1から9までの数字視認では,どの被験者も複雑性指標のMultiscale Entropy値と機械学習のガウス過程回帰によって,3電極のうちどれか1つの電極で視認の判別の可能性があることが分かった。これは脳波からブレインマシンインターフェイスの可能性があることを示せた。
アルツハイマー型認知症の脳波からの認知重軽度の分類では,同期性の指標であるPhase Lag Index値を求め電極別算術平均と機械学習のt-SNE法を組み合わせることで,機械分類の損失値が大幅に改善された。この解析手法は認知機能の状態を脳波から定量的に評価する上で有効な手段になり得ることを示せた。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (8 results)

All 2022 2021 2020 2019

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 5 results) Presentation (3 results) (of which Invited: 1 results)

  • [Journal Article] Memory Storage Systems Utilizing Chaotic Attractor-Merging Bifurcation2022

    • Author(s)
      Sou Nobukawa, Nobuhiko Wagatsuma, Haruhiko Nishimura, Keiichiro Inagaki, Teruya Yamanishi
    • Journal Title

      IEEE Access

      Volume: 10 Pages: 15699-15706

    • DOI

      10.1109/access.2022.3149055

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Recent Trends of Controlling Chaotic Resonance and Future Perspectives2021

    • Author(s)
      Sou Nobukawa, Haruhiko Nishimura, Nobuhiko Wagatsuma, Keiichiro Inagaki, Teruya Yamanishi, Tetsuya Takahashi
    • Journal Title

      Frontiers in Applied Mathematics and Statistics

      Volume: 7 Pages: 1-6

    • DOI

      10.3389/fams.2021.760568

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Chaos-Chaos Intermittency Synchronization Controlled by External Feedback Signals in Chua's Circuits2020

    • Author(s)
      Sou Nobukawa, Hirotaka Doho, Natsusaku Shibata, Haruhiko Nishimura, Teruya Yamanishi
    • Journal Title

      IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences

      Volume: E103.A Issue: 1 Pages: 303-312

    • DOI

      10.1587/transfun.2019EAP1081

    • NAID

      130007778782

    • ISSN
      0916-8508, 1745-1337
    • Year and Date
      2020-01-01
    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Classification Methods Based on Complexity and Synchronization of Electroencephalography Signals in Alzheimer's Disease2020

    • Author(s)
      S. Nobukawa, T. Yamanishi, S. Kasakawa, H. Nishimura, M. Kikuchi, T. Takahashi
    • Journal Title

      Frontiers in Psychiatry

      Volume: 11 Pages: 1-12

    • DOI

      10.3389/fpsyt.2020.00255

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] High Phase Synchronization in Alpha Band Activity in Older Subjects with High Creativity2020

    • Author(s)
      S. Nobukawa, T. Yamanishi, K. Ueno, K. Mizukami, H. Nishimura, T. Takahashi
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 14 Pages: 1-11

    • DOI

      10.3389/fnhum.2020.583049

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 脳波解析 -アルツハイマー病患者と健常者の脳波の機械学習-2020

    • Author(s)
      山西輝也
    • Organizer
      イノベーション・リサーチ交流会「AI/IoTで変わる医療,変わる社会」ふくいオープンイノベーション推進機構実施事業
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 脳波の同期解析とt-SNEの融合によるアルツハイマー病の診断精度と重軽度分類の向上2019

    • Author(s)
      山西輝也
    • Organizer
      第29回インテリジェント・システム・シンポジウム
    • Related Report
      2019 Research-status Report
  • [Presentation] IQと創造性テストからの高齢健常者の脳波解析2019

    • Author(s)
      山西輝也
    • Organizer
      電子情報通信学会 MEとバイオサイバネティックス&ニューロコンピューティング 合同研究会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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