• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Theoretical study on the oscillation and synchronization mechanisms in biological rhythms and the proposal of experimental studies

Research Project

Project/Area Number 18K11464
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 61040:Soft computing-related
Research InstitutionThe University of Tokyo

Principal Investigator

Kori Hiroshi  東京大学, 大学院新領域創成科学研究科, 教授 (80435974)

Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords同期 / ネットワーク / 生物リズム / 同期現象 / 概日リズム
Outline of Final Research Achievements

As described in this report, we were able to achieve five main research results:
(1) stability of oscillator networks against noise and optimal network structure, (2) population dynamics and pattern formation of fibroblasts, (3) phase description theory of chaotic oscillators, (4) contribution to experimental studies of biological clocks, and (5) effect of fluid interaction of oscillators on transport efficiency.

Academic Significance and Societal Importance of the Research Achievements

複数の自由度を持つ非線形現象のメカニズムの理解に、数理的アプローチは必須である。本研究では、生命システムにおける振動と同期のメカニズムと役割を理解するための数理的理論枠組みをいくつか構築することができた。また、細胞集団の動きやカオス振動と行った、振動・同期現象と密接な関係がある現象についても理論研究を進めることができた。これらの研究成果は非線形・散逸系の物理学や応用数学の発展に貢献するだけでなく、工学分野や生命科学分野においても活用されることが期待される。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (14 results)

All 2022 2020 2019 2018 Other

All Journal Article (4 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 4 results,  Open Access: 2 results) Presentation (7 results) (of which Int'l Joint Research: 3 results,  Invited: 3 results) Remarks (3 results)

  • [Journal Article] Phase and frequency linear response theory for hyperbolic chaotic oscillators2022

    • Author(s)
      Toenjes Ralf、Kori Hiroshi
    • Journal Title

      Chaos: An Interdisciplinary Journal of Nonlinear Science

      Volume: 32 Issue: 4 Pages: 043124-043124

    • DOI

      10.1063/5.0064519

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A light-induced small G-protein gem limits the circadian clock phase-shift magnitude by inhibiting voltage-dependent calcium channels.2022

    • Author(s)
      Matsuo M, Seo K, Taruno A, Mizoro Y, Yamaguchi Y, Doi M, Nakao R, Kori H, Abe T, Ohmori H, Tominaga K, Okamura H
    • Journal Title

      Cell Rep

      Volume: 39 Issue: 8 Pages: 110844-110844

    • DOI

      10.1016/j.celrep.2022.110844

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effects of coating culture dishes with collagen on fibroblast cell shape and swirling pattern formation2020

    • Author(s)
      Hashimoto Kei、Yamashita Kimiko、Enoyoshi Kanako、Dahan Xavier、Takeuchi Tatsu、Kori Hiroshi、Gotoh Mari
    • Journal Title

      Journal of Biological Physics

      Volume: 46 Issue: 4 Pages: 351-369

    • DOI

      10.1007/s10867-020-09556-3

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Noise stability of synchronization and optimal network structures2020

    • Author(s)
      Katoh Yuriko、Kori Hiroshi
    • Journal Title

      Chaos: An Interdisciplinary Journal of Nonlinear Science

      Volume: 30 Issue: 1 Pages: 013148-013148

    • DOI

      10.1063/1.5121341

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Presentation] Dynamics and efficiency of one-dimensional coupled-oscillator model in low Reynolds number flows2022

    • Author(s)
      粟偉巍, 郡宏
    • Organizer
      日本物理学会 第77回年次大会(2022年)
    • Related Report
      2021 Research-status Report
  • [Presentation] Tackling complex dynamics in biology and chemistry with phase oscillator models2020

    • Author(s)
      Hiroshi KORI
    • Organizer
      MECO 45
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Tackling and playing with biological phenomena using phase oscillator models: jet lag, locomotion, etc.2019

    • Author(s)
      Hiroshi Kori
    • Organizer
      ICMMA 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Mathematical and Experimental Study on Jet Lag: Practical Method to Accelerate Recovery2019

    • Author(s)
      Hiroshi Kori
    • Organizer
      The 20th RIES-HOKUDAI International Symposium
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 電力網モデルのノイズ安定性とベイスン安定性2019

    • Author(s)
      郡宏
    • Organizer
      第74回年次大会(2019年),
    • Related Report
      2018 Research-status Report
  • [Presentation] 同期の新しいシナリオ:不安定状態への接近による遍歴的秩序化2018

    • Author(s)
      郡宏, I.Z. Kiss
    • Organizer
      2018年秋季大会
    • Related Report
      2018 Research-status Report
  • [Presentation] ストークス流れ中のスイマー集団の振動と遊泳方向の秩序化2018

    • Author(s)
      郡宏、Antonio Gamez
    • Organizer
      2018年度 RIMS研究集会『生物流体力学の展望』
    • Related Report
      2018 Research-status Report
  • [Remarks] 郡 宏(KORI, Hiroshi)

    • URL

      http://www.hk.k.u-tokyo.ac.jp/kori/index-jp.html

    • Related Report
      2021 Research-status Report
  • [Remarks] Hiroshi KORI

    • URL

      http://www.hk.k.u-tokyo.ac.jp/kori/index-jp.html

    • Related Report
      2020 Research-status Report
  • [Remarks] Hiroshi Kori

    • URL

      http://www.hk.k.u-tokyo.ac.jp/kori/index-jp.html

    • Related Report
      2019 Research-status Report 2018 Research-status Report

URL: 

Published: 2018-04-23   Modified: 2024-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi