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Innovative Exposure Assessment System for Nano Products to use DMA-GED-ICP/MS.

Research Project

Project/Area Number 18K11677
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 64010:Environmental load and risk assessment-related
Research InstitutionKyoto University

Principal Investigator

Matsui Yasuto  京都大学, 環境安全保健機構, 教授 (50533501)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords曝露評価 / ナノマテリアル / 加速試験 / 元素分析 / カーボンナノチューブ / 炭素繊維強化プラスチック / 摩耗試験 / 吸入性粉塵 / テーバー摩耗試験機 / 電子顕微鏡 / 個数濃度モニタリング装置 / 気体試料導入装置
Outline of Final Research Achievements

First, elemental oxide nanoparticles were generated, and we confirmed that the correlation between particle size and ICP/MS counts. Next, we tried to construct an exposure assessment system by using a taber abrasion in the chamber connected to HEPA filter to distribute the outside air. The samples were selected from general resin materials (CFRP, PMMA) containing CNTs. The amount of nanomaterials emitted was quantified as elemental concentrations by connecting a DMA-GED-ICP/MS to that chamber. The cobalt concentration correlate significantly with the dose of particle generation. This result indicate that generated CNTs containing or adhered particles can detect easily to focus the element.

Academic Significance and Societal Importance of the Research Achievements

過去のナノマテリアルに関する研究では、原材料の影響評価に関する報告が大半であったが、製品レベルの曝露評価に関する報告は少なく、本研究はその方法を提案する初期的な研究と位置づけられる。また国内外で曝露評価方法に関するガイドラインは既に存在するものの、製品レベルへの適応は難しい現状があった。しかしながら、本研究で確立した方法を用いることで、既存のガイドラインに対する優位性を定量的に示すことができ、事業者自身による曝露評価およびリスクの自主的管理の加速が期待できる。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (8 results)

All 2021 Other

All Int'l Joint Research (1 results) Presentation (7 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results)

  • [Int'l Joint Research] University of Oregon/Department of Chemistry and Biochemistry(米国)

    • Related Report
      2021 Annual Research Report
  • [Presentation] Exposure Assessment of Market Products Including Nanomaterial in General Use and Disposal Process2021

    • Author(s)
      Matsui Yasuto, Kimoto Shigeru, Yoneda Minoru,
    • Organizer
      American Association for Aerosol Research
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Observation of particles’ deposition by the difference of particle size and charge number in a chamber2021

    • Author(s)
      Yoshiro Sadatani, Shigeru Kimoto, Yasuto Matsui, Chiaki Murai, Shota Shakagori, Minoru Yoneda
    • Organizer
      American Association for Aerosol Research
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluation System for the Indoor Environment for Sheltering in a House2021

    • Author(s)
      Shigeru Kimoto, Yoshiro Sadatani, YasutoMatsui, Minoru Yoneda
    • Organizer
      Asian Aerosol Conference
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ナノ粒子の表面修飾と細胞内への取り込み量との関係性2021

    • Author(s)
      松井康人
    • Organizer
      粉体工学会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Evaluation of micro/nano particle generated in the abrasion process of CNT added CFRP2021

    • Author(s)
      Shota Shakagori, Yasuto Matsui
    • Organizer
      Nanosafe
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluation of Deposition Rate Constant of a Test Chamber for Sheltering in a House2021

    • Author(s)
      Wen-Lu Wang, Shigeru Kimoto, Yasuto Matsui, Minoru Yoneda
    • Organizer
      Asian Aerosol Conference
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Improvement and Assessment of Indoor Air Quality in Sheltering House in the Later Stage of Emergency Based on Deposition Rate2021

    • Author(s)
      Wen-Lu Wang, Nobuyuki Kato, Shigeru Kimoto, Yasuto Matsui, Minoru Yoneda
    • Organizer
      American Association for Aerosol Research
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research

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Published: 2018-04-23   Modified: 2023-01-30  

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