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Study of the relationship between hierarchic structure of track potential and track structure produced by quantum beams

Research Project

Project/Area Number 18K11935
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 80040:Quantum beam science-related
Research InstitutionNational Institutes for Quantum Science and Technology

Principal Investigator

Moribayashi Kengo  国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員 (70354975)

Project Period (FY) 2018-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2022: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2021: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywordsイオン照射 / 二次電子の運動 / トラックポテンシャル / 熱平衡化 / プラズマ / シミュレーション / クラスターイオン / 熱平衡状態 / 動径線量 / 重イオン / 二次電子 / 飛跡構造 / ポアソン方程式 / 重イオンビーム / 熱膨張 / 簡便式 / 重イオンビーム科学 / 極紫外線自由電子レーザー
Outline of Final Research Achievements

In this study, we aimed to elucidate the relationship between the hierarchic structure of track potential (which is space distribution of energy deposition) and track structure (which is the electric field) and the production processes of plasma irradiated by quantum beams. This study is expected to clarify the reason why heavy ion has high biological effect in cancer therapy.
We treated irradiation of heavy ions and cluster ions. To elucidate the relationship and the production processes mentioned before, we studied (i)probabilities of secondary electrons escaping the track potential, (ii)thermalization of secondary electrons, and (iii)radial dose, which is the dose in the local reaction as a function of the distance from the incident ion path, through simulations, where a secondary electron is the electron produced by ionization due to incident ion impact.

Academic Significance and Societal Importance of the Research Achievements

世界で初めて重イオン及びクラスターイオン照射で生じる二次電子がトラックポテンシャルに捕獲されるシミュレーションモデルを開発し、二次電子の熱平衡化、及びプラズマを生成過程をシミュレートすることに成功した。このプラズマが生成することは、理論的には、予測されており、理論で求めたプラズマがもたらす生物効果は重粒子線癌治療の治療計画に導入されているが、不明な点も多かった。この研究でこの生成過程等を詳細に解明した。

Report

(7 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (40 results)

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article (10 results) (of which Peer Reviewed: 10 results,  Open Access: 4 results) Presentation (29 results) (of which Int'l Joint Research: 10 results,  Invited: 4 results) Book (1 results)

  • [Journal Article] Multi-scale simulations aiming to advance heavy ion beam cancer therapy2023

    • Author(s)
      Moribayashi K.、Matsubara H.、Yonetani Y.、Shikazono N.
    • Journal Title

      AIP Conference Proceedings

      Volume: 2756 Pages: 30001-30001

    • DOI

      10.1063/5.0140807

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of closeness between a few atoms forming a cluster ion passing through water on the motion of secondary electrons and radial dose2023

    • Author(s)
      Kengo Moribayashi
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 208 Pages: 110870-110870

    • DOI

      10.1016/j.radphyschem.2023.110870

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of the thermalization of secondary electron energies on plasma formation during the irradiation of heavy ions2023

    • Author(s)
      Kengo Moribayashi
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 537 Pages: 129-132

    • DOI

      10.1016/j.nimb.2023.02.014

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of Coulomb interaction between secondary electrons on plasma formation due to heavy-ion irradiation2022

    • Author(s)
      Moribayashi Kengo
    • Journal Title

      Journal of Physics: Conference Series

      Volume: 2207 Issue: 1 Pages: 012020-012020

    • DOI

      10.1088/1742-6596/2207/1/012020

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proton-Cluster-Beam Lethality and Mutagenicity in Bacillus subtilis Spores2021

    • Author(s)
      Yoshihiro Hase, Katsuya Satoh, Atsuya Chiba, Yoshimi Hirano, Kengo Moribayashi, and Kazumasa Narumi
    • Journal Title

      Quantum Beam Science

      Volume: 5 Issue: 3 Pages: 25-25

    • DOI

      10.3390/qubs5030025

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Debye shield formed by track potential and transport of secondary electrons in heavy ion irradiation2021

    • Author(s)
      Kengo Moribayashi
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 184 Pages: 109436-109436

    • DOI

      10.1016/j.radphyschem.2021.109436

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Application of atomic and molecular data for plasma production and cancer therapy by heavy particle irradiation2020

    • Author(s)
      Kengo Moribayashi
    • Journal Title

      Jpn. J. Applied Phys.

      Volume: 59 Issue: SH Pages: SH0801-SH0801

    • DOI

      10.35848/1347-4065/ab7c11

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Heat diffusion in heavy-ion beam irradiation2019

    • Author(s)
      Kengo Moribayashi
    • Journal Title

      X-Ray Spectrometry

      Volume: 48 Issue: 6 Pages: 708711-708711

    • DOI

      10.1002/xrs.3115

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Erratum to “Radial dose distribution model independent of species of incident ions”2019

    • Author(s)
      Moribayashi Kengo
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 458 Pages: 190-195

    • DOI

      10.1016/j.nimb.2019.07.009

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Application of simple formulas to track potential in heavy-ion-beam simulation2018

    • Author(s)
      K. Moribayashi
    • Journal Title

      Transactions of the Materials Research Society of Japan

      Volume: 43 Issue: 5 Pages: 267-270

    • DOI

      10.14723/tmrsj.43.267

    • NAID

      130007493491

    • ISSN
      1382-3469, 2188-1650
    • Year and Date
      2018-10-01
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 単色X線ナノサイズ領域照射で生じる光電子の加熱効果2024

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会 2024年春季大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Development of a simulation model aiming to study plasma formation and thermalization of secondary electrons in heavy ion irradiation2023

    • Author(s)
      Kengo Moribayashi
    • Organizer
      21st International Conference on Radiation Effects in Insulators (REI-21)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Radial dose simulations in the irradiation of cluster ions2023

    • Author(s)
      Kengo Moribayashi
    • Organizer
      34th IUPAP Conference on Computational Physics (CCP2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 放射線の局所領域照射で生じる自由電子による加熱とその医療・産業応用2023

    • Author(s)
      森林 健悟
    • Organizer
      「プラズマの分光診断と原子分子素過程の研究フロンティア」研究会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 重イオンビーム照射における二次電子の初期エネルギー分布の影響2023

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会2023年春季大会
    • Related Report
      2022 Research-status Report
  • [Presentation] 重イオン照射で生成する二次電子の運動の熱平衡化2022

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会2022年秋季大会
    • Related Report
      2022 Research-status Report
  • [Presentation] Application of heavy ion plasma to understand treatment mechanism of heavy ion cancer therapy2022

    • Author(s)
      Kengo Moribayashi
    • Organizer
      ICRP-11/GEC2022
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Simulation study to aim to elucidate biological effect due to fast highly-charged ion irradiation2022

    • Author(s)
      Kengo Moribayashi
    • Organizer
      20th International Conference on Physics of Highly Charged Ion
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Theory and simulations for plasma created by swift heavy ions2022

    • Author(s)
      Kengo Moribayashi
    • Organizer
      29th international conference on atomic collisions in solids & 11th international symposium on swift heavy ions in matter
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] クラスターイオンが作る動径線量のシミュレーション2022

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会 第77回年次大会
    • Related Report
      2021 Research-status Report
  • [Presentation] MULTI-SCALE SIMULATIONS AIMING TO ADVACE HEAVY ION BEAM CANCER THERAPY2021

    • Author(s)
      K. Moribayashi, H. Matsubara, Y. Yonetani, N. Shikazono
    • Organizer
      1st International Conference on Computational Science & Data Analytics (COMDATA)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Application of plasma simulation and theory to heavy ion cancer therapy2021

    • Author(s)
      Kengo Moribayashi
    • Organizer
      Conference on Computational Physics (CCP) 2021
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 重イオンビーム照射で形成する自己組織化とDNA損傷の可能性2021

    • Author(s)
      森林 健悟
    • Organizer
      量子生命科学会第3回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 重イオンビーム照射による散逸構造,自己組織化形成の可能性2021

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会2021年秋季大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 重イオンビーム照射におけるデバイ遮蔽の生成過程2021

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会 第76回年次大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 磁場がイオンビームの生物効果を増大させる理由の検討:熱膨張仮説2020

    • Author(s)
      森林 健悟
    • Organizer
      量子生命科学会 第2回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 重粒子がん治療におけるプラズマ物理の役割2020

    • Author(s)
      森林 健悟
    • Organizer
      京都大学 プラズマ科学研究ユニットセミナー
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 磁場がイオンビームの生物効果を増大させる理由の検討:熱膨張仮説2020

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会 2020年秋季大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Plasma formed by track potential and transport of secondary electrons in heavy ion irradiation on surfaces2020

    • Author(s)
      Kengo Moribayashi
    • Organizer
      第21回「イオンビームによる表面・界面の解析と改質」特別研究会
    • Related Report
      2020 Research-status Report
  • [Presentation] 重粒子線がん治療における原子分子・プラズマ物理の役割2020

    • Author(s)
      森林 健悟
    • Organizer
      第45回原子衝突学会年会
    • Related Report
      2020 Research-status Report
  • [Presentation] Application of atomic and molecular data to heavy ion beam plasma production and further, heavy ion beam cancer therapy2019

    • Author(s)
      Kengo Moribayashi
    • Organizer
      International Workshop on Atomic and Molecular Data for Plasma Applications
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Application of nano-sized low-temperature plasma produced from heavy ion irradiation to heavy ion cancer therapy2019

    • Author(s)
      Kengo Moribayashi
    • Organizer
      ICPIG &ICRP10
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 重イオンビームの新規動径線量シミュレーションモデル:従来のモデルとの比較2019

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会2019年 秋季大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 動径線量シミュレーションに使用した次世代型粒子モデルの現状と今後の展望2019

    • Author(s)
      森林 健悟
    • Organizer
      原子衝突学会第44回年会
    • Related Report
      2019 Research-status Report
  • [Presentation] イオンビームに平行に掛かる磁場の生物影響:熱膨張仮説2019

    • Author(s)
      森林 健悟
    • Organizer
      高崎サイエンスフェスタ
    • Related Report
      2019 Research-status Report
  • [Presentation] 重イオンビーム照射におけるブラッグピーク付近での温度上昇2019

    • Author(s)
      森林 健悟
    • Organizer
      日本物理学会第74回年次大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 重イオンビーム照射によって生じる熱膨張が引き起こすDNA損傷の可能性2018

    • Author(s)
      森林 健悟
    • Organizer
      原子衝突学会第43回年会
    • Related Report
      2018 Research-status Report
  • [Presentation] Role of ion impact ionization cross sections in radiation biology using swift highly charged ion beams2018

    • Author(s)
      Kengo Moribayashi
    • Organizer
      19th International Conference: Physics of Highly Charged Ion
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 重イオンビームの動径線量シミュレーション2018

    • Author(s)
      森林 健悟
    • Organizer
      理研セミナー
    • Related Report
      2018 Research-status Report
    • Invited
  • [Book] Application of laser-driven particle acceleration2018

    • Author(s)
      N. Shiakazono, K. Moribayashi, P.R. Bolton
    • Total Pages
      14
    • Publisher
      CRC press Taylor & Francis group, Boca Raton, London, New York
    • ISBN
      9780429445101
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2025-01-30  

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