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Development of the sleep evaluation method using salivary hormone secretion in infants

Research Project

Project/Area Number 18K14806
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 45060:Applied anthropology-related
Research InstitutionShiga University

Principal Investigator

Ohira Masako  滋賀大学, 教育学部, 准教授 (40616190)

Project Period (FY) 2018-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords幼児 / 睡眠 / 唾液 / ホルモン / DHEA / コルチゾール / 子ども
Outline of Final Research Achievements

There are significant practical limitations in assessing the quality of a toddler’s sleep. In response to this, the applicant focused on hormones, especially dehydroepiandrosterone (DHEA), as a new indicator. In the present study, we tested the secretion of DHEA during waking hours in toddlers by comparing it with a conventional index. In addition, the usefulness and limitations of the index as a sleep assessment will be clarified, and the scope of applicability and methodological limitations will be validated by the results of the study scientifically. The results showed a significant positive correlation between DHEA secretion immediately after waking up and the variable "sleep quality." They also showed that the amount of DHEA secretion immediately after waking up reflected the "sleep quality" in toddlers as well as in adults, suggesting that this may be a possible sleep assessment index.

Academic Significance and Societal Importance of the Research Achievements

子どもは自分の睡眠状態を話すことが出来ないし、実験室内で多くの機械を装着して、睡眠の質を測定することも難しい。これに対して、研究代表者は起床後のわずかな唾液のみで、子どもの睡眠評価を実現できないかを実験的に検証した。その結果、起床直後のある性ホルモンの分泌量が増えるほど、子どもの「睡眠の質」が良い傾向にあることが明らかになった。更なる検証を続けることで、新たな睡眠評価手法を構築できるかもしれない。

Report

(3 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • Research Products

    (14 results)

All 2019 2018

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (10 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Effects of LED lighting exposure during sleep on endocrine and autonomic nervous system activity2019

    • Author(s)
      Hasegawa‐Ohira Masako、Kato Yoshimune、Nomura Shusaku
    • Journal Title

      IEEJ Transactions on Electrical and Electronic Engineering

      Volume: 14 Issue: 6 Pages: 894-898

    • DOI

      10.1002/tee.22879

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the difference in bathing methods after intense exercise on sleep quality2019

    • Author(s)
      大平雅子、山田雄大
    • Journal Title

      Japanese Journal of Health and Research

      Volume: 40 Issue: 0 Pages: 31-38

    • DOI

      10.32279/jjhr.40.0_31

    • NAID

      130007734334

    • ISSN
      2432-602X, 2434-8481
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 短時間仮眠前の香り呈示が自律神経活動に及ぼす影響2019

    • Author(s)
      岡野慎也、横江顕彦、五十棲計、大平雅子
    • Journal Title

      睡眠と環境

      Volume: 15 Pages: 3-9

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 乳幼児の日中活動量が起床後のホルモン分泌に及ぼす影響2018

    • Author(s)
      大平雅子
    • Journal Title

      発達研究

      Volume: 32 Pages: 27-36

    • NAID

      40021631717

    • Related Report
      2018 Research-status Report
  • [Presentation] Impact of diapers on a sleep-wake rhythm of 2-month old infants; evaluation based on cortisol awakening response2019

    • Author(s)
      Tange A, Tagami E, Mitsui K, Sasaki T, Hayashi M, H. Ohira M .
    • Organizer
      World Sleep 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of odor presentation before awakening from a short sleep on alertness2019

    • Author(s)
      Okano S,H. Ohira M.
    • Organizer
      World Sleep 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 短時間睡眠における起床前の香り呈示が起床後の注意力に及ぼす影響2019

    • Author(s)
      岡野慎也,大平雅子
    • Organizer
      第28回日本睡眠環境学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 睡眠環境評価における生化学的指標の活用可能性2019

    • Author(s)
      大平雅子
    • Organizer
      日本生理人類学会 感性・脳科学研究部会&睡眠研究部会 合同会合
    • Related Report
      2019 Annual Research Report
  • [Presentation] 目覚まし音の違いが覚醒度および覚醒後の持続的な注意力に及ぼす影響2019

    • Author(s)
      大平雅子,朝倉大晟
    • Organizer
      日本睡眠学会第44回定期学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 目覚まし音の違いが覚醒度及び覚醒後の持続的な注意力に及ぼす影響2019

    • Author(s)
      朝倉大晟,大平雅子.
    • Organizer
      第45回滋賀県学校保健学会
    • Related Report
      2018 Research-status Report
  • [Presentation] Influence of Daytime Activity on Hormone Secretion in Saliva after Awakening in Infants2018

    • Author(s)
      H. Ohira M, Masuda S.
    • Organizer
      24rd Congress of the European Sleep Research Society(ESRS2018)
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] クーリングダウンの実施が睡眠の質や翌日の疲労感に及ぼす影響2018

    • Author(s)
      大平雅子,横江顕彦,五十棲計.
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 短時間仮眠前の香り呈示が仮眠の質に及ぼす影響2018

    • Author(s)
      五十棲計,岡野慎也,大平雅子.
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 午睡時の香り呈示が子どもの睡眠に及ぼす影響2018

    • Author(s)
      岡田駿平,大平雅子.
    • Organizer
      日本学校保健学会第65回学術大会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2021-02-19  

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