| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Intracellular signaling mechanism of meloxicam is found to involve Akt/PI3K molecules for inhibition of Parkinson's disease progression, but the other mechanisms are unknown. In this study, applicant attempted to elucidate the mechanism of action of meloxicam, and identified the proteins involved in the mechanism of action of meloxicam. This clarification has advanced the development of meloxicam as a novel drug for the inhibition of Parkinson's disease progression.
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