APPLE (Association between the Pathology of Bipolar Disorder and Light Exposure in Daily Life) cohort study
| Project/Area Number |
18K15529
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52030:Psychiatry-related
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| Research Institution | Fujita Health University |
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Principal Investigator |
Esaki Yuichi 藤田医科大学, 医学部, 客員講師 (60793693)
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| Project Period (FY) |
2018-04-01 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 精神科 / 概日リズム / 睡眠 / 気分 / 光曝露 / 双極性障害 / リズム / サーカディアンリズム / 精神神経科学 |
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| Outline of Final Research Achievements |
The aim of this project is to clarify the association between the pathology of bipolar disorder and light exposure in daily life. I found that light exposure is significantly associated with depressive and manic symptoms, sleep quality, and circadian rhythm in patients with bipolar disorder.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究結果により、日常生活の光曝露は双極性障害の病状（睡眠の質、うつ症状、躁症状、クロノタイプ、肥満、再発）と関連していることが明らかになった。双極性障害患者さんは、日中は可能な限り光を浴びて、夜間は真っ暗な部屋で眠ることが病状安定につながることが示唆された。
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Report
(5 results)
Research Products
(12 results)
