| Project/Area Number |
18K15548
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Kobe University |
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Principal Investigator |
Yada Ryuichi 神戸大学, 医学部附属病院, 特命技術員 (50782421)
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| Project Period (FY) |
2018-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | インビボ線量計 / ミクロ線量計 / MEMS / インビボ線量測定 |
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| Outline of Final Research Achievements |
Two types of dosimeters using BaFBr:Eu and KCl as detector materials have been developed.
The performance was evaluated using a clinical radiation therapy system , and it was found that the performance was sufficient for the specifications of the in vivo dosimeter. In terms of energy dependence, BaFBr:Eu was found to over-response to the scattering radiation generated in the body due to its high effective atomic number. To avoid this problem, we developed a dosimeter probe using KCl with a low effective atomic number.
The high accuracy of both dosimeters can be ensured by appropriately selecting the intended use. In particular, the BaFBr:Eu probe was successfully made into a much smaller size probe than the conventional dosimeter probe.
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| Academic Significance and Societal Importance of the Research Achievements |
この線量計により、リアルタイム補正による適応放射線治療を可能にし、治療精度を向上させることで治療成績の向上につながる。線量計で測定した実際の照射線量と臨床結果が紐づいたデータを収集できることで、実臨床での新たな線量対効果（副作用）の関係性を発見できる。これにより、従来の関係性を見直せるだろうと考えている。
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