Development of a dose-prediction system for reducing patient's radiation dose in image-guided radiotherapy
Project/Area Number |
18K15584
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 52040:Radiological sciences-related
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Research Institution | Niigata University |
Principal Investigator |
TANABE SATOSHI 新潟大学, 医歯学総合病院, 助教 (80743898)
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Project Period (FY) |
2018-04-01 – 2021-03-31
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Project Status |
Completed (Fiscal Year 2020)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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Keywords | 医学物理 / 被ばく線量 / 線量予測 / 患者位置合わせ / Fiducialマーカー / 画像誘導放射線治療 / 動体追跡放射線治療 / SyncTraX FX4 / 被曝線量 |
Outline of Final Research Achievements |
In this study, we investigated the optimal imaging conditions in order to reduce patient exposure dose while ensuring high position accuracy in image-guided radiotherapy (IGRT). As a result of applying this condition for patients who received radiation therapy for the head region, the exposure dose could be reduced to less than 0.50 mGy while ensuring the positional accuracy of 1 mm. We also evaluated the exposure dose during fluoroscopy in real-time tumor-tracking radiotherapy for lung cancer, and showed that the entrance skin dose can be reduced to less than 100 mGy by setting the gating window to 4 mm.
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Academic Significance and Societal Importance of the Research Achievements |
本研究は、画像誘導放射線治療における位置合わせ精度と被ばく線量の相反する2つの因子を考慮して最適なX線撮像条件を検討した初めての研究である。実際に頭部放射線治療を受けた患者の位置合わせにおいて、本研究によって検討した撮像条件を適応した結果、位置合わせ精度が低下することなく、患者被ばく線量を低減できたことから、患者への恩恵は計り知れず、その社会的意義は大きい。本研究によって得られた成果は、画像誘導放射線治療における被ばく線量管理を展開するための基盤の確立に寄与する。
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Report
(4 results)
Research Products
(56 results)
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[Journal Article] The association between oral candidiasis and severity of chemoradiotherapy-induced dysphagia in head and neck cancer patients: A retrospective cohort study2020
Author(s)
Hirotake Saito, Ryusuke Shodo, Keisuke Yamazaki, Kouji Katsura, Yushi Uek, Toshimichi Nakano, Tomoya Oshikane, Nobuko Yamana, Satoshi Tanabe, Satoru Utsunomiya, Atsushi Ohta, Eisuke Abe, Motoki Kaidu, Ryuta Sasamoto, Hidefumi Aoyama
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Journal Title
Clinical and Translational Radiation Oncology
Volume: 20
Pages: 13-18
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] The neurocognitive function change criteria after whole-brain radiation therapy for brain metastasis, in reference to healthrelated quality of life changes: a prospective observation study2020
Author(s)
Toshimichi Nakano, Hidefumi Aoyama, Hirotake Saito, Satoshi Tanabe, Kensuke Tanaka, Katsuya Maruyama, Tomoya Oshikane, Atsushi Ohta, Eisuke Abe, Motoki Kaidu
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Journal Title
BMC Cancer
Volume: 20(1)
Issue: 1
Pages: 66-76
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] 多発脳転移に対する単一アイソセンタ照射法における患者セットアップの 並進誤差が線量不確かさに及ぼす影響2020
Author(s)
中野 永, 棚邊 哲史, 宇都宮 悟, 中野 智成, 斎藤 紘丈, 滝澤 健司, 山田 巧, 坂井 裕則, 太田 篤, 阿部 英輔, 海津 元樹, 青山 英史
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Journal Title
定位的放射線治療
Volume: 24
Pages: 1-9
Related Report
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[Journal Article] Selection criteria for 3D conformal radiotherapy versus volumetric-modulated arc therapy in highgrade glioma based on normal tissue complication probability of brain2019
Author(s)
Satoshi Tanabe, Haruna Takahashi, Hirotake Saito, Atsushi Ohta, Toshimichi Nakano, Ryuta Sasamoto, Miki Shioi, Satoru Utsunomiya, Eisuke Abe, Motoki Kaidu, Hidefumi Aoyama
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Journal Title
Journal of Radiation Research
Volume: 60(2)
Issue: 2
Pages: 249-256
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Clinical commissioning of a new patient positioning system, SyncTraX FX4, for intracranial stereotactic radiotherapy2018
Author(s)
Satoshi Tanabe, Osamu Umetsu, Toshikazu Sasage, Satoru Utsunomiya, Ryota Kuwabara, Toshiki Kuribayashi, Hiromasa Takatou, Gen Kawaguchi, Hidefumi Aoyama
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Journal Title
Journal of Applied Clinical Medical Physics
Volume: 19(6)
Issue: 6
Pages: 149-158
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] 新潟大学医歯学総合病院医学物理士レジデントコース:5年の成果と課題2020
Author(s)
宇都宮悟, 棚邊哲史, 中野永, 坂井まどか, 高橋春奈, 久島尚隆, 滝澤健司, 成田啓廣, 早川岳英, 山田巧, 坂井裕則, 金沢勉, 笠原敏文, 笹本龍太, 海津元樹, 和田真一, 青山英史
Organizer
日本放射線腫瘍学会第33回学術大会
Related Report
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[Presentation] 椎体骨転移緩和照射におけるSmart Alignerを用いた位置照合精度評価2020
Author(s)
桑原亮太, 棚邊哲史, 栗林俊輝, 捧俊和, 梅津修, 宇都宮悟, 皆川有弘, 上村直史, 佐藤豊, 金子隼汰, 池田紀子, 高頭浩正, 川口弦
Organizer
日本放射線腫瘍学会第33回学術大会
Related Report
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[Presentation] Safe Distance Limit between the Target and Intestinal Tract in Real-Time Tracking Radiotherapy for Liver Tumors2019
Author(s)
Kawaguchi G, Tanabe S, Utsunomiya S, Umetsu O, Sasage T, Kuwabara R, Kuribayashi T, Kamimura T, Satou Y, Takatou H, Aoyama H
Organizer
ASTRO 61st Annual Meeting
Related Report
Int'l Joint Research
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