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Development of plastic scintillation dosimeter for 4D dose measurement

Research Project

Project/Area Number 18K15607
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionChiba University (2021-2022)
Tokyo Women's Medical University (2018-2020)

Principal Investigator

Tsuneda Masato  千葉大学, 大学院医学研究院, 特任講師 (60800753)

Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords4D dosimetry / Plastic scintillator / VMAT / SBRT / patient specific QA / dose reconstruction / CCD camera / シンチレータ / 4次元線量計測 / 患者QA / MR画像誘導即時適応放射線治療 / 線量分布計測 / プラスチックシンチレータ / イメージングシステム / モンテカルロシミュレーション / 患者QA/QC / プラスチックシンチレータイメージングシステム / 4次元線量分布 / 高精度放射線治療 / 患者個別QAQC / 医学物理学 / 4次元放射線治療
Outline of Final Research Achievements

To test the measurement technique of the 4D dose distribution measured image by capturing the scintillation light generated using a plastic scintillator and a scintillating screen. Our system constituted a column shaped plastic scintillator covered by a scintillating screen, a conical mirror and a cooled CCD camera. The 3D dose distribution was reconstructed from each captured image using the our original dose reconstruction algorithm. This algorithm includes the blurring correction deconvolution, image scaling, reconstruction and dose conversion. And, we developed the Monte Carlo simulation to compare with the measured 4D dose distribution. We tested the dose linearity, dose rate dependence and gamma analysis for the dose distributions.
In this study, our system concept can act as a suitable technique for measuring the 4D dose distribution from the basic characteristic and the gamma results.

Academic Significance and Societal Importance of the Research Achievements

従来より、高精度放射線治療計画は治療開始前に患者QAとして点線量計測や多次元線量分布検証が行われてきた。しかし、肺や肝臓といった呼吸性移動を伴う部位ではinterplay effectといった腫瘍へ付与される線量の不確定性が生じる問題がある。このような治療においては、同様の患者QAではなく、”腫瘍へ正確に線量付与が行えるプランであるか”を検証する必要がある。そこで、本研究で4次元線量分布計測が可能なシンチレータとCCDカメラを用いたシステムを開発し、そのパフォーマンスを検証した。
これに加えて、腫瘍の動きを模擬することで実際に腫瘍へ線量付与が可能であるか、新たな線量評価指標が構築できる。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (15 results)

All 2023 2022 2021 2020 2019 2018

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (13 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results)

  • [Journal Article] Elekta Unity MR-linac commissioning: mechanical and dosimetry tests.2023

    • Author(s)
      Tsuneda M, Abe K, Fujita Y, Ikeda Y, Furuyama Y, Uno T.
    • Journal Title

      J Radiat Res

      Volume: 64 Issue: 1 Pages: 73-84

    • DOI

      10.1093/jrr/rrac072

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Plastic scintillation dosimeter with a conical mirror for measuring 3D dose distribution2021

    • Author(s)
      Tsuneda Masato、Nishio Teiji、Ezura Takatomo、Karasawa Kumiko
    • Journal Title

      Medical Physics

      Volume: 48 Issue: 10 Pages: 5639-5650

    • DOI

      10.1002/mp.15164

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Presentation] Elekta Unityによる強度変調放射線治療施行時のinterplay effect に起因する線量誤差の評価:ファントム検証2023

    • Author(s)
      恒田雅人、阿部幸太、藤田幸男、橋本拓磨、池田洋平、宇野隆
    • Organizer
      第36回高精度放射線学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Delivery accuracy of VMAT on two beam-matched linacs2022

    • Author(s)
      Masato Tsuneda, Kota Abe, Yukio Fujita, Yukinao Abe, Ryo Morimoto, Takuma Hashimoto, Takashi Uno
    • Organizer
      22nd Asia-Oceania Congress on Medical Physics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 千葉大学におけるElekta UnityのQAQC戦略 QA/QC procedure for Elekta Unity2022

    • Author(s)
      恒田雅人
    • Organizer
      第124回日本医学物理学会学術大会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Plastic scintillation dosimeter with a conical mirror for measuring 3D dose distribution2022

    • Author(s)
      Masato Tsuneda, Teiji Nishio, Takashi Uno
    • Organizer
      第123回日本医学物理学会学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Elekta Unityにおけるoff-center Winston-Lutz試験の開発2022

    • Author(s)
      恒田雅人、阿部幸太、藤田幸男、池田洋平、古山良延、宇野隆
    • Organizer
      日本放射線腫瘍学会第35回学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Plastic scintillation dosimeter with a conical mirror for measuring 3D dose distribution2022

    • Author(s)
      Masato Tsuneda, Teiji Nishio, and Takashi Uno
    • Organizer
      The 123rd Scientific Meeting of the Japan Society of Medical Physics
    • Related Report
      2021 Research-status Report
  • [Presentation] Development of the scintillator imaging system for the measurement of the dose volume with high-sampling rate2020

    • Author(s)
      Masato Tsuneda, Teiji Nishio, Takatomo Ezura and Kumiko Karasawa
    • Organizer
      62nd AAPM annual meeting
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Measurement of the three-dimensional dose distribution using scintillator imaging system2019

    • Author(s)
      Masato Tsuneda, Teiji Nishio, Takatomo Ezura and Kumiko Karasawa
    • Organizer
      61st AAPM annual meeting
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of the scintillator imaging system for measurement of 3D dose distribution2019

    • Author(s)
      Masato Tsuneda, Teiji Nishio, Takatomo Ezura and Kumiko Karasawa
    • Organizer
      AOCMP&EPSM 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Investigation of the dosimetric impact of breathing motion on lung VMAT-SBRT delivery using a 3D motion platform and a water tank-type lung phantom2019

    • Author(s)
      Masato Tsuneda, Teiji Nishio, Takatomo Ezura, Yaichiro Hashimoto and Kumiko Karasawa
    • Organizer
      AOCMP&EPSM 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Measurement of the three-dimensional dose distribution using scintillator imaging system2019

    • Author(s)
      Masato Tsuneda, Teiji Nishio, Takatomo Ezura and Kumiko Karasawa
    • Organizer
      American Association of Physicists in Medicine
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] シンチレータイメージングシステムを用いた4次元線量分布測定の基礎検討2019

    • Author(s)
      恒田雅人、西尾禎治、江面崇智、唐澤久美子
    • Organizer
      第32回高精度放射線外部照射部会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Kompeito Shot System: Development of a novel verification system for 3D/4D beam alignment (2)2018

    • Author(s)
      恒田雅人、西尾禎治、齋藤明登、小澤修一、唐澤久美子、永田靖
    • Organizer
      日本放射線腫瘍学会 第31回 学術大会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2024-01-30  

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