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Development of dose verification system using the polymer gel dosimeter

Research Project

Project/Area Number 18K15614
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionNational Cancer Center Japan

Principal Investigator

Iijima Kotaro  国立研究開発法人国立がん研究センター, 中央病院, 医学物理士 (50792909)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsゲル線量計 / 放射線治療 / 品質保証 / 品質管理 / 線量検証 / PVA-Iゲル線量計 / 平板型ゲル線量計 / BNCT / 放射線測定 / 放射線測定機器開発 / ポリマーゲル線量計 / QA / MRIdian / PAGAT / MAGAT / 小線源治療
Outline of Final Research Achievements

The objective of this grant project was to develop a system to verify a dose distribution using a gel dosimeter and to present a new verification method for increasingly advanced radiation therapy machine.
We have published our results in many forums on the application of the polymer gel dosimeters to the MR image-guided radiation therapy machine and on the dosimetry of the boron neutron capture therapy using a complex-forming gel dosimeters.
The application to small-source radiation therapy was reported conclusively by others during the period of this grant, and thus was removed from the scope of this research. Thus, although some parts of the research could not be carried out as originally planned, the research on polymer gel dosimeters carried out by this research grant has yielded satisfactory results.

Academic Significance and Societal Importance of the Research Achievements

本助成事業による研究で得られた成果は、先進化が著しい放射線治療に対して十分な影響を与えると考える。
現状の放射線治療では、放射線の3次元的な線量分布は断片的に測定されているため、「真」の線量分布を測定することはできない。しかし、本研究ではポリマーゲル線量計を用いることで放射線の線量分布を3次元的に取得できることが示され、そのために必要なシステムや手法を提示することができた。
このことから本助成事業の学術的・社会的意義は非常に大きいと考える。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (12 results)

All 2021 2020 2019 2018

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (9 results)

  • [Journal Article] Configuration analysis of the injection position and shape of the gel spacer in gynecologic brachytherapy2021

    • Author(s)
      Iijima Kotaro、Murakami Naoya、Nakamura Satoshi、Nishioka Shie、Chiba Takahito、Kuwahara Junichi、Takemori Mihiro、Nakayama Hiroki、Kashihara Tairo、Okuma Kae、Takahashi Kana、Inaba Koji、Igaki Hiroshi、Okamoto Hiroyuki、Itami Jun
    • Journal Title

      Brachytherapy

      Volume: 20 Issue: 1 Pages: 95-103

    • DOI

      10.1016/j.brachy.2020.08.021

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A dosimetric and centeredness comparison of the conventional and novel endobronchial applicators: A preliminary study2021

    • Author(s)
      Iijima Kotaro、Murakami Naoya、Okamoto Hiroyuki、Nakamura Satoshi、Nishioka Shie、Chiba Takahito、Kuwahara Junichi、Nakayama Hiroki、Takemori Mihiro、Aikawa Ako、Yoshihiro Shibata、Kashihara Tairo、Takahashi Kana、Inaba Koji、Okuma Kae、Igaki Hiroshi、Nakayama Yuko、Itami Jun
    • Journal Title

      Brachytherapy

      Volume: 20 Issue: 2 Pages: 467-477

    • DOI

      10.1016/j.brachy.2020.11.005

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Performance of a newly designed end-to-end phantom compatible with magnetic resonance-guided radiotherapy systems2021

    • Author(s)
      Iijima K, Okamoto H, Nishioka S, Sakasai T, Nakamura S, Chiba T, Kaga K, Takemori M, Nakayama H, Miura Y, Fujiyama D, Tsunoda Y, Igaki H, Katsuta S, Itami J.
    • Journal Title

      Medical Physics

      Volume: 48 Issue: 11 Pages: 7541-7551

    • DOI

      10.1002/mp.15153

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Presentation] Dose-distribution measurement in the treatment plan of CyberKnife using 2D poly(vinyl alcohol)-Iodide gel dosimeter2021

    • Author(s)
      Kotaro Iijima, Mihiro Takemori, Hironori Murakami, Miki Kosaka, Toshimitsu Sofue, Satoshi Nakamura, Takahito Chiba, Shie Nishioka, Hiroki Nakayama, Keita Kaga, Hiroshi Igaki, Hiroyuki Okamoto, Jun Itami
    • Organizer
      The 121th Scientific Meeting of the JSMP
    • Related Report
      2021 Annual Research Report
  • [Presentation] Basic study of the PVA-I flat gel dosimeter in star shot analysis2020

    • Author(s)
      Kotaro Iijima, Hiroyuki Okamoto, Mihiro Takemori, Satoshi Nakamura, Shie Nishioka, Hiroki Nakayama, Junichi Kuwahara, Miyuki Murata, Yuki Miura, Hironori Murakami, Shoichi Katsuta and Jun Itami
    • Organizer
      The 119th Scientific Meeting of the JSMP
    • Related Report
      2020 Research-status Report
  • [Presentation] 平板型PVA-Iゲル線量計のFence試験への応用2020

    • Author(s)
      飯島康太郎、竹森望弘、中村哲志、西岡史絵、千葉貴仁、中山広貴、桑原潤一、村田美幸、三浦悠記、久木裕也、井垣浩、岡本裕之、伊丹純
    • Organizer
      日本放射線腫瘍学会第33回学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Preliminary study of polymer gel dosimeter for QA in MRI-guided radiotherapy system2019

    • Author(s)
      Takemori M, Iijima K, Okamoto H, et al.
    • Organizer
      The 117th Scientific Meeting of the JSMP
    • Related Report
      2019 Research-status Report
  • [Presentation] 平板型PVA-I線量計のスターショットを用いた基礎検証2019

    • Author(s)
      飯島康太郎, 岡本裕之, 竹森望弘, 他.
    • Organizer
      第8回3次元ゲル線量計研究会
    • Related Report
      2019 Research-status Report
  • [Presentation] ホウ素入りPVA-I線量計のBNCTに対する適応性の検討2019

    • Author(s)
      竹森 望弘, 中村 哲志, 飯島 康太郎, 他
    • Organizer
      第8回3次元ゲル線量計研究会
    • Related Report
      2019 Research-status Report
  • [Presentation] ポリマーゲル線量計を用いたMR画像誘導放射線治療装置のQAに関する基礎研究2018

    • Author(s)
      竹森望弘
    • Organizer
      第7回3次元ポリマーゲル線量計研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] MR画像誘導放射線治療装置に対する3Dゲル線量計の適合性の基礎的検討2018

    • Author(s)
      飯島康太郎
    • Organizer
      第32回高精度放射線外部照射部会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Preliminary study of polymer gel dosimeter for QA in MRI-guided radiotherapy system2018

    • Author(s)
      竹森望弘
    • Organizer
      第117回日本医学物理学会学術大会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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