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Development Collapsed Cone Convolution Dose Calculation Engine for MRI-Linac

Research Project

Project/Area Number 18K15617
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionTohoku University

Principal Investigator

Ito Kengo  東北大学, 大学病院, 助手 (40705076)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
KeywordsMRI-Linac / 高速線量計算 / CCC法 / 磁場 / モンテカルロ法 / コンボリューション法 / CollapsedConeConvolution
Outline of Final Research Achievements

In this study, we developed a fast dose calculation algorithm for MRI-Linac (MRL) which was newly introduced clinical use in Japan. In radiotherapy, the response to treatments are evaluated using dose distributions, which are the distributions of energy depositions by the radiation in the patient body. Since the MRL treats the patient in the magnetic field, the dose distributions need to be incorporated the effect of the magnetic field. Currently used algorithms can derive dose distributions with high accuracy, however, it require long computation times. In this study, we developed an algorithm for MRL by incorporating a new correction into the conventional method, Collapsed Cone Convolution methods.

Academic Significance and Societal Importance of the Research Achievements

本研究で開発したアルゴリズムは,高速に線量分布を導出することができる点で特徴的である.現在世界中で使用されているアルゴリズムは,GPUを用いた超並列計算を用いることで臨床上許容される時間内で線量分布を取得している.本研究で開発したアルゴリズムもGPUを使用することでさらなる高速化も可能となっており,精度評価が完遂すれば臨床応用も可能であると考える.短時間に線量分布を取得できることで患者待機時間は短縮され,装置のスループットも向上する.同じ時間内で従来よりも多くの患者がMRI-Linacで治療されることになる.

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (2 results)

All 2022 2019

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] Evaluation of the electron transport algorithm in magnetic field in EGS5 Monte Carlo code2022

    • Author(s)
      Ito Kengo、Kadoya Noriyuki、Katsuta Yoshiyuki、Tanaka Shohei、Dobashi Suguru、Takeda Ken、Jingu Keiichi
    • Journal Title

      Physica Medica

      Volume: 93 Pages: 46-51

    • DOI

      10.1016/j.ejmp.2021.12.001

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Presentation] MRI-Linac用CCC-based線量計算アルゴリズムの有効性2019

    • Author(s)
      伊藤謙吾
    • Organizer
      日本放射線腫瘍学会第32回学術大会
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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