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Effect of exercise intervention after atrial fibrillation ablation

Research Project

Project/Area Number 18K15840
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 53020:Cardiology-related
Research InstitutionThe University of Tokyo

Principal Investigator

Oguri Gaku  東京大学, 医学部附属病院, 助教 (00750001)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Keywords運動療法 / 心房細動 / カテーテルアブレーション / 心臓リハビリ / 心臓リハビリテーション / アブレーション / リハビリテーション
Outline of Final Research Achievements

The aim of this present study is to evaluate the effects of exercise intervention on cardiac function, evaluation of heart failure and recurrence rate in patients with atrial fibrillation who had catheter ablation. Due to the influence of the covid-19 infection, the situation where individual postoperative training was not possible continued, and the target number of cases has not been reached, but indicators such as heart failure tend to decrease. This study suggests its effectiveness of exercise intervention.

Academic Significance and Societal Importance of the Research Achievements

心房細動カーテルアブレーション術後の運動療法による介入がその再発予防や心臓の負荷の軽減にどのような影響を及ぼすかはわかっていない。今回の研究成果として、まだ研究の中間ではあるものの心不全改善等が示唆された。今後、研究を継続し、解析結果が待たれるものの、今回の研究により術後の生活の指導やリハビリテーションは重要な意味を持つことが考えられた。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (8 results)

All 2021 2020 2019 2018

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (6 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA12021

    • Author(s)
      Oguri Gaku、Nakajima Toshiaki、Kikuchi Hironobu、Obi Shotaro、Nakamura Fumitaka、Komuro Issei
    • Journal Title

      Heliyon

      Volume: 7 Issue: 1 Pages: e05816-e05816

    • DOI

      10.1016/j.heliyon.2020.e05816

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] What is the mechanism of irregular pacing spikes? Pacing failure, sensing failure, or something else? A case report2020

    • Author(s)
      Oguri Gaku、Kojima Toshiya、Fujiu Katsuhito、Komuro Issei
    • Journal Title

      European Heart Journal - Case Reports

      Volume: 4 Issue: 3 Pages: 1-4

    • DOI

      10.1093/ehjcr/ytaa065

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Presentation] Involvement of chloride channel (Clic) in myocardial fibrosis of pressure-overload model mice and dilated cardiomyopathy patients2021

    • Author(s)
      Gaku Oguri, Toshiaki Nakajima, Seitaro Nomura, Hironobu Kikuchi, SyotaroObi, Teruo Inoue, Issei Komuro
    • Organizer
      第85回日本循環器学会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Involvement of Chloride Channel (clic) in Myocardial Fibrosis of Pressure-overload Model Mice and Dilated Cardiomyopathy Patients2020

    • Author(s)
      Gaku Oguri, Toshiaki Nakajima, Seitaro Nomura, Takafumi Nakajima, Hironobu Kikuchi, SyotaroObi, Teruo Inoue, Issei Komuro
    • Organizer
      AHA 2020 (virtual)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 圧負荷モデルマウスにおける心室筋細胞のイオンチャネルのリモデリング:単一細胞RNAseq解析による検討2019

    • Author(s)
      小栗岳, 野村征太郎, 中島敏明, 菊地宏信, 小尾正太郎, 井上晃男, 小室一成
    • Organizer
      第67回 日本心臓病学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2019-09-13
    • Related Report
      2019 Research-status Report
  • [Presentation] 肺静脈隔離術を契機に重複下大静脈が検出された一例2018

    • Author(s)
      小栗岳, 小島敏弥, 吉田由理子, 松永紘, 大島司, 松田淳, 松原巧, 福馬伸章, 嵯峨亜希子, 荷見映理子, 藤生克仁, 小室一成
    • Organizer
      カテーテルアブレーション関連秋季大会
    • Place of Presentation
      沖縄
    • Year and Date
      2018-11-09
    • Related Report
      2018 Research-status Report
  • [Presentation] Rhythmiaマッピングシステムを用いてmulti-components accessory pathwaysを証明し得た潜在性WPW症候群の一例2018

    • Author(s)
      小栗岳, 小島敏弥, 吉田由理子, 松永紘, 大島司, 松田淳, 松原巧, 福馬伸章, 嵯峨亜希子, 荷見映理子, 藤生克仁, 小室一成
    • Organizer
      カテーテルアブレーション関連秋季大会
    • Place of Presentation
      沖縄
    • Year and Date
      2018-11-09
    • Related Report
      2018 Research-status Report
  • [Presentation] Appearance of Premature Atrial and Ventricular Contractions after Switching from Brand to Generic Cibenzoline2018

    • Author(s)
      Oguri G, Fujiu K, Kojima T, Hasumi E, Komuro I
    • Organizer
      APHRS2018
    • Place of Presentation
      台北
    • Year and Date
      2018-10-17
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-04-23   Modified: 2022-01-27  

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