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Relationship between sex cycles and Interferon-gamma releasing assay test results

Research Project

Project/Area Number 18K16186
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 54030:Infectious disease medicine-related
Research InstitutionKeio University

Principal Investigator

UWAMINO Yoshifumi  慶應義塾大学, 医学部(信濃町), 講師 (60748789)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords結核 / 検査 / 性周期 / インターフェロンγ遊離試験 / 性ホルモン
Outline of Final Research Achievements

We performed clinical studies to investigate the hypothesis that sex cycles affects the test results of Interferon gamma releasing assay (IGRA) among premenopausal females. According to our study results, there were no apparent relationship between sex cycles and IGRA test results, suggesting IGRA tests can be performed regardless of sex cycles among premenopausal females.

Academic Significance and Societal Importance of the Research Achievements

インターフェロンγ遊離試験(IGRA)は、医療従事者の結核曝露時健診などで用いられることが多いが、医療従事者には閉経前女性の比率が多く含まれるため、検査結果が性周期の影響を受けると適切に結核曝露時のリスク評価ができない可能性が懸念されたが、本研究の成果によりその懸念を払拭することができた。これは、結核曝露に対する感染管理を行なっていく上で有用な知識となりうる。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (1 results)

All 2019

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Low serum estradiol levels are related to Mycobacterium avium complex lung disease: a cross-sectional study.2019

    • Author(s)
      Uwamino Y, Nishimura T, Sato Y, Tamizu E, Asakura T, Uno S, Mori M, Fujiwara H, Ishii M, Kawabe H, Murata M, Hasegawa N.
    • Journal Title

      BMC Infect Dis.

      Volume: 19(1) Issue: 1 Pages: 1055-1055

    • DOI

      10.1186/s12879-019-4668-x

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access

URL: 

Published: 2018-04-23   Modified: 2022-01-27  

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