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Venous structure created by a bio-3D printer for transplantaion

Research Project

Project/Area Number 18K16252
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 55010:General surgery and pediatric surgery-related
Research InstitutionThe University of Tokyo

Principal Investigator

Kokudo Takashi  東京大学, 医学部附属病院, 助教 (40802921)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords人工血管 / バイオ3Dプリンター / Bio-3D printer / スフェロイド
Outline of Final Research Achievements

Vascular graft was made using bio-3D printer. The vascular graft was transplanted to a pig and confirmed the patency of the graft. We are now preparing for publication.

Academic Significance and Societal Importance of the Research Achievements

本研究で作成した人工血管は臨床応用が可能となれば、今後多くの患者の治療に使用されると考えられる。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (24 results)

All 2019 2018

All Journal Article (11 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 11 results,  Open Access: 4 results) Presentation (12 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results) Book (1 results)

  • [Journal Article] Assessment of Preoperative Liver Function for Surgical Decision Making in Patients with Hepatocellular Carcinoma2019

    • Author(s)
      Kokudo Takashi、Hasegawa Kiyoshi、Shirata Chikara、Tanimoto Meguri、Ishizawa Takeaki、Kaneko Junichi、Akamatsu Nobuhisa、Arita Junichi、Demartines Nicolas、Uldry Emilie、Kokudo Norihiro、Halkic Nermin
    • Journal Title

      Liver Cancer

      Volume: 8 Issue: 6 Pages: 447-456

    • DOI

      10.1159/000501368

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Albumin?Indocyanine Green Evaluation (ALICE) grade combined with portal hypertension to predict post‐hepatectomy liver failure2019

    • Author(s)
      Shirata Chikara、Kokudo Takashi、Arita Junichi、Akamatsu Nobuhisa、Kaneko Junichi、Sakamoto Yoshihiro、Kokudo Norihiro、Hasegawa Kiyoshi
    • Journal Title

      Hepatology Research

      Volume: 印刷中 Issue: 8 Pages: 942-949

    • DOI

      10.1111/hepr.13327

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A novel liver-specific fluorescent anti-cancer drug delivery system using indocyanine green2019

    • Author(s)
      Inagaki Yoshinori、Kokudo Takashi、Kamiya Mako、Uno Shin-nosuke、Sato Masumitsu、Kaneko Junichi、Kokudo Norihiro、Urano Yasuteru、Hasegawa Kiyoshi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 3044-3044

    • DOI

      10.1038/s41598-019-39269-0

    • Related Report
      2019 Research-status Report 2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hepatectomy in patients with inherited blood coagulation disorders can be safely performed with adequate coagulation factor replacement2019

    • Author(s)
      Kobayashi Kosuke、Kokudo Takashi、Yamaguchi Takamune、Shirata Chikara、Uldry Emilie、Akamatsu Nobuhisa、Arita Junichi、Kaneko Junichi、Yasumoto Atsushi、Demartines Nicolas、Hasegawa Kiyoshi、Halkic Nermin
    • Journal Title

      Haemophilia

      Volume: 25 Issue: 3 Pages: 463-467

    • DOI

      10.1111/hae.13759

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Stent placement for benign portal vein stenosis following pancreaticoduodenectomy in a hybrid operating room2018

    • Author(s)
      Sawai Yutaka、Kokudo Takashi、Sakamoto Yoshihiro、Takao Hidemasa、Kazami Yusuke、Nishioka Yujiro、Akamatsu Nobuhisa、Arita Junichi、Kaneko Junichi、Hasegawa Kiyoshi
    • Journal Title

      BioScience Trends

      Volume: 12 Issue: 6 Pages: 641-644

    • DOI

      10.5582/bst.2018.01296

    • NAID

      130007575206

    • ISSN
      1881-7815, 1881-7823
    • Year and Date
      2018-12-31
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Surgical treatment for monolobular Caroli's disease ‒ Report of a 30-year single center case series2018

    • Author(s)
      Yamaguchi Takamune、Cristaudi Alessandra、Kokudo Takashi、Uldry Emilie、Demartines Nicolas、Halkic Nermin
    • Journal Title

      BioScience Trends

      Volume: 12 Issue: 4 Pages: 426-431

    • DOI

      10.5582/bst.2018.01162

    • NAID

      130007485015

    • ISSN
      1881-7815, 1881-7823
    • Year and Date
      2018-08-31
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Albumin-Indocyanine Green Evaluation Grading System Predicts Post-Hepatectomy Liver Failure for Biliary Tract Cancer2018

    • Author(s)
      Miyazaki Yoshihiro、Kokudo Takashi、Amikura Katsumi、Takahashi Amane、Ohkohchi Nobuhiro、Sakamoto Hirohiko
    • Journal Title

      Digestive Surgery

      Volume: 36 Issue: 1 Pages: 13-19

    • DOI

      10.1159/000486142

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hepatic angiomyolipoma detected using computed tomography2018

    • Author(s)
      Miyazaki Yoshihiro、Kokudo Takashi、Takahashi Amane、Amikura Katsumi、Sakamoto Hirohiko
    • Journal Title

      ANZ Journal of Surgery

      Volume: 89 Issue: 4

    • DOI

      10.1111/ans.14156

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Liver Resection for Hepatocellular Carcinoma in Patients with Renal Dysfunction2018

    • Author(s)
      Shirata Chikara、Hasegawa Kiyoshi、Kokudo Takashi、Yamashita Suguru、Yamamoto Satoshi、Arita Junichi、Akamatsu Nobuhisa、Kaneko Junichi、Sakamoto Yoshihiro、Kokudo Norihiro
    • Journal Title

      World Journal of Surgery

      Volume: 42 Issue: 12 Pages: 4054-4062

    • DOI

      10.1007/s00268-018-4698-3

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Liver Regeneration is Preserved After At Least Four Repeated Liver Resections for Hepatocellular Carcinoma2018

    • Author(s)
      Yamaguchi Takamune、Kokudo Takashi、Akamatsu Nobuhisa、Kaneko Junichi、Arita Junichi、Sakamoto Yoshihiro、Kokudo Norihiro、Hasegawa Kiyoshi
    • Journal Title

      World Journal of Surgery

      Volume: 42 Issue: 12 Pages: 4070-4080

    • DOI

      10.1007/s00268-018-4714-7

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Innovative treatment for hepatocellular carcinoma (HCC)2018

    • Author(s)
      Kaneko Junichi、Kokudo Takashi、Inagaki Yoshinori、Hasegawa Kiyoshi
    • Journal Title

      Translational Gastroenterology and Hepatology

      Volume: 3 Pages: 78-78

    • DOI

      10.21037/tgh.2018.10.04

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 肝細胞癌に対するICG蛍光法を用いた系統的肝切除術2019

    • Author(s)
      國土 貴嗣, 石沢 武彰, 渡邉 元己, 真木 治文, 市田 晃彦, 金子 順一, 赤松 延久, 有田 淳一, 長谷川 潔
    • Organizer
      第81回日本臨床外科学会総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 外科的見地からみた進行肝細胞癌に対する肝癌診療ガイドライン2017の検証2019

    • Author(s)
      國土 貴嗣、阿部 学、長谷川 潔
    • Organizer
      第55回日本肝臓学会総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 肝癌診療ガイドラインとAASLD/BCLC ガイドラインの比較検討2019

    • Author(s)
      國土貴嗣、石沢武彰、赤松延久、有田淳一、金子順一、長谷川潔
    • Organizer
      第119 回日本外科学会定期学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] Assessment of Preoperative Liver Function in Patients with Hepatocellular Carcinoma2019

    • Author(s)
      Kokudo T, Shirata C, Tanimoto M, Arita J, Kaneko J, Akamatsu N, Ishizawa T, Hasegawa K
    • Organizer
      APPLE2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Surgical treatment for advanced stage hepatocellular carcinoma2018

    • Author(s)
      Kokudo Takashi, Shirata Chikara, Abe Satoru, Arita Junichi, Kaneko Junichi, Akamatsu Nobuhisa, Ishizawa Takeaki, Hasegawa Kiyoshi
    • Organizer
      第80回日本臨床外科学会総会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] Digital Subtraction Angiography(DSA)を用いた ハイブリッドアンギオ室の肝胆膵外科領域における使用経験2018

    • Author(s)
      國土貴嗣、阪本良弘、西岡裕次郎、長田梨比人、山下俊、有田淳一、赤松延久、金子順一、大倉直樹*、高尾英正*、長谷川潔
    • Organizer
      第118回日本外科学会定期学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 進行肝細胞癌に対する肝切除の成績2018

    • Author(s)
      國土 貴嗣、阿部 学、長谷川 潔
    • Organizer
      第104回日本消化器病学会総会
    • Related Report
      2018 Research-status Report
  • [Presentation] アルブミン、ICG15分値を用いた新しい肝機能評価分類(ALICE score)に基づいた肝移植適応決定2018

    • Author(s)
      國土貴嗣、白田力、赤松延久、金子順一、 有田淳一、阪本良弘、長谷川潔
    • Organizer
      第36回日本肝移植研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] Surgical treatment for hepatocellular carcinoma with macroscopic vascular invasion or multiple tumors2018

    • Author(s)
      Takashi Kokudo, Satoru Abe, Junichi Arita, Junichi Kaneko, Nobuhisa Akamatsu, Yoshihiro Sakamoto, Kiyoshi Hasegawa
    • Organizer
      第30回日本肝胆膵外科学会学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] ICGを中心とした肝細胞癌の新規術前肝機能評価指標の開発2018

    • Author(s)
      國土貴嗣、谷本芽弘理、有田淳一、 金子順一、赤松延久、阪本良弘、長谷川潔
    • Organizer
      第54回日本肝癌研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] Assessment of preoperative liver function in patients with hepatocellular carcinoma - ALICE grade2018

    • Author(s)
      Kokudo Takashi, Miyazaki Yoshihiro, Amikura Katsumi, Takahashi Amane, Kaneko Junichi, Akamatsu Nobuhisa, Arita Junichi, Sakamoto Yoshihiro, Sakamoto Hirohiko, Hasegawa Kiyoshi
    • Organizer
      第73回 日本消化器外科学会総会
    • Related Report
      2018 Research-status Report
  • [Presentation] Assessment of preoperative liver function in patients undergoing liver resection; The ALICE grade2018

    • Author(s)
      Kokudo Takashi, Shirata Chikara, Toda Takeo, Nishioka Yujiro, Yamaguchi Takamune, Arita Junichi, Kaneko Junichi, Akamatsu Nobuhisa, Sakamoto Yoshihiko, Hasegawa KiyoshiK
    • Organizer
      13th IHPBA World Congress
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Book] 外科2018

    • Author(s)
      國土 貴嗣, 影山 優美子, 網倉 克己, 長谷川 潔, 坂本 裕彦
    • Publisher
      (株)南江堂
    • Related Report
      2018 Research-status Report

URL: 

Published: 2018-04-23   Modified: 2023-01-30  

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